Greene Tweed’s Post

Premature seal failure can lead to unexpected maintenance and lost production time. Greene Tweed can help recommend the right seal shape and material to ensure reliable operations - just as we did for a global #pharmaceutical company. Read the case study below on how our FDA-certified #ffkm, Chemraz SD625, helped extend a maintenance cycle from under 1 year to more than 3 years! #autoclaves #lifesciences #sealingsolutions #fda #reliability

💡 In the pharmaceutical industry, the sterilization of complex liquid media requires state-of-the-art equipment, designed to guarantee safety, efficiency and compliance. ACTINI's pharmaceutical sterilizers meet these requirements with innovative, high-performance solutions.   Cutting-edge technologies: ✔️ Aseptic Tubular Heat Exchangers: total asepsis and optimal heat transfer, even for highly viscous products. ✔️Energy recovery systems: up to 90% reduction in energy consumption. ✔️Automation and traceability: optimized cycles and advanced management for total compliance.   Hygienic design and safety: ✔️cGMP standards: with low roughness finishing, high grade welding, no retention zone, perfect cleaning. ✔️Manufacturing with 316L or Hastelloy according to the products ✔️Integrated CIP/SIP: continuous asepsis and reduced downtime. ✔️Versatility: suitable for nutrient media, plant extracts, cosmetic gels, and more.   Want to know more about our continuous sterilizer?  

🌟 Understanding Filtration Technologies in Pharmaceutical Manufacturing 🌟 Filtration is a critical operation in the pharmaceutical industry, enabling the production of high-purity intermediates and APIs. Let's explore three commonly used filtration systems: 1️⃣ Agitated Nutsche Filter & Dryer (ANFD) Unique Features: Closed vessel system for vacuum or pressure filtration, equipped with a multipurpose agitator. Key Advantages: Vacuum/pressure filtration possible Inert gas atmosphere maintenance High solvent recovery and safety compliance Minimal toxic vapor release Temperature control via jacketed design 🔧 Functions of the Agitator: Keeps slurry fluidized during filtration Prevents cake cracking and vacuum operation disruptions Facilitates cake washing and discharge 2️⃣ Pressure/Vacuum Nutsche Filter Similar to ANFD but lacks an agitator, necessitating manual operations for uniformity. Considerations: Requires personal protection for manual adjustments Ideal for processes where agitation isn’t critical 3️⃣ Centrifuges Common Types: Vertical Axis Batch Mode: Uses centrifugal force for efficient separation. Peeler Centrifuge: Mechanically peels and discharges the cake. Inverting Bag Centrifuge: Turns the filter bag inside out for faster discharge. Filtration Calculations: Centrifugal force, gravitational force, and their ratios determine scalability. Each of these systems offers unique benefits for achieving process efficiency, safety, and product quality in pharmaceutical manufacturing. Choosing the right system depends on your specific process needs. #PharmaceuticalEngineering #Filtration #ANFD #Centrifuges #ProcessExcellence #APIManufacturing

Introducing the Exergy PUREX Steam Sample Cooler: Revolutionizing Clean Steam Sampling for the Pharmaceutical Industry! At Exergy, we are committed to enhancing safety and efficiency in pharmaceutical operations. Our PUREX Steam Sample Cooler delivers reliable, clean steam samples with: ✔️ Fully Portable Cart-Based Solution ✔️ ASME BPE Compliant for industry standards ✔️ Automated Operation for simplicity and safety ✔️ Ergonomic Design and easy-to-use HMI ✔️ On-Board Cooling and Condensate Tanks for a cleaner environment ✔️ Self-Sanitization Mode for easy maintenance Designed to meet the rigorous demands of the pharmaceutical industry, this cooler ensures fast setup and precise sample collection. Perfect for areas without cooling water connections, it makes steam sampling safer and more efficient. 📈 Key Specifications: Clean Steam Pressure: 3.5 bar (50 psi) Steam Temperature: 148°C (298°F) Flow Rate: 80 kg/hr (175 lbs/hr) Heat Exchanged: 47 kW (160K BTU/hr) Ready to optimize your clean steam sampling process? Learn more about the PUREX Steam Sample Cooler and how it can improve your operations today! #Pharmaceutical #SteamSampling #CleanSteam #Innovation #Safety #ExergySolutions #ProcessEfficiency #Sustainablity #HeatExchangers #HeatTransfer #Sterility #Portability

In the world of pharmaceutical manufacturing, water for injection (WFI) plays a vital role that often goes unseen. WFI is produced using various methods and equipment to ensure its purity and compliance with regulatory standards. The quality and purity of WFI are paramount to ensuring the safety and efficacy of pharmaceutical products. Introduce you our state-of-the-art Membrane-Based Generation of Water for Injection system, producing high-quality WFI that meets the required standards. 🚀 Key Features: ☑ Final Ultrafiltration: cutting-edge membrane technology, including pretreatment ultrafiltration, microfiltration, nanofiltration, and more to replace distillation. This ensures compliance with various pharmacopoeia standards and WHO regulations for WFI, offering flexible process routes for pharmaceutical companies. ☑ In-Line Microbial Detection: Real-time data query, meeting 21 CFR Part 11 requirements. Our technology identifies both active and inactive microbial particles, enabling instantaneous monitoring and rapid pollution risk identification through trend analysis. ☑ Ambient WFI System: Compared to WFI by distillation process, our membrane-based WFI system tends to offer savings in terms of capital costs and operating and utility costs，being ideal for container cleaning and dissolution of APIs. ✨ Advantages: 💰 Cost-Effective: Lower equipment investment and reduced energy consumption with a smaller footprint. 🔬 Enhanced Disinfection: Medium pressure UV lamp ensures simultaneous dechlorination and disinfection. 🔄 Improved Performance: Compared to traditional PW equipment, our system prevents rouging and reduces particle contamination. 🔧 Easy Maintenance: User-friendly design simplifies daily operation for smooth system performance. 🛠 Customized Solutions: Tailored services to meet individual customer demands. Join us in optimizing your pharmaceutical water purification! Together, let’s shape a future characterized by unmatched quality, safety, and sustainability, ultimately advancing patient care. 📧 info@austar.com.hk #austargroup #pharmaceuticalwater #purification #WFI #equipment #system

Clean in place (CIP) procedures are essential for the dairy, bioprocessing, and pharmaceutical industries. These procedures allow for routine cleaning without dismantling equipment and piping, in contrast with clean out of place (COP) procedures. CIP can clean effectively without excessively compromising process uptime, which is why this type of cleaning is preferred for large and/or self-contained surfaces like tanks, pumps, piping, etc. CIP can be done both manually and automatically. The five considerations of CIP are TACTT. #wearemerrick

𝐎𝐮𝐫 𝐞𝐱𝐩𝐞𝐫𝐭𝐢𝐬𝐞 𝐟𝐨𝐫 𝐲𝐨𝐮𝐫 𝐩𝐡𝐚𝐫𝐦𝐚 𝐚𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧 High-quality compressed air is required in a variety of applications in the pharma industry – for example for tableting, cleaning, conveying, packaging, regulating valves and cylinders – and in clean rooms, which is a good example of where our expertise is particularly valuable. Since some of the pharmaceutical production steps in clean rooms require compressed air, its quality is a critical factor. But as compressed air can be used in all classes of clean rooms, the purity requirements vary. When used an energy carrier in motors and pumps, for example, the compressed air does not come into contact with the product. It must, however, comply with the quality requirements for the ambient air into which the compressed air is released. Another example is where compressed air is used to dry the washed primary vessels in clean rooms before they are filled with the product or where liquids are filled by the blow-fill-seal method. In such applications the compressed air may not contain any germs or particles. Whatever your compressed air application may be, our experts can advise on how to meet the required pharmaceutical standards and ensure compliance with regulatory requirements. Just get in touch: info@beko-technologies.co.uk #CompressedAir #PharmaIndustry #BlowFillSeal #PharmaProcesses #PharmaManufacturing

Let’s explore the working principles of direct heating trays. How do they help safeguard product quality in pharma, for instance? With drug production, pharmaceutical manufacturers require: 1. Precise thermal management of heat-sensitive materials 2. Ability to dry at lower temperatures 3. Preservation of efficacy and safety of materials 4. Safeguarding product quality 5. Ease of operation and maintenance Tray dryers offer an advanced solution for drying heat-sensitive products. This is particularly the case when operating under vacuum conditions. Trays containing feedstock are directly heated by conduction. Warming shelves or heater plates maintain thermal uniformity. So, what are the features and advantages of direct heating tray dryers? 1. Uniform Heat Transfer ↳ Prevents hot and cold spots 2. Optimised for Heat-Sensitive Materials ↳ Maintains material structural integrity / chemical stability 3. Efficiency ↳ Precise control over temperature and vacuum conditions 4. Streamlined Loading and Unloading ↳ Facilitates ease of operation and maintenance Through their innovative use of vacuum conditions and superior heat transfer capabilities, direct heating tray dryers offer a robust solution to the challenges of drying heat-sensitive materials in pharma production. Read more and access our brochure: https://bit.ly/442SPfZ #traydryers #vacuumtraydryers #pharmaceuticalmanufacturing #heatingtrays #drugmanufacturing #pharmaprocessing

🚀 Transform Your Pharmaceutical Operations with Monoflo Centrifugal Pumps! 🚀 In the pharmaceutical industry, precision, reliability, and compliance are key. That’s why Monoflo Centrifugal Pumps are the perfect solution for handling critical applications such as: 💧 Chilled Water Transfer. 💧 Industrial Water Transfer. 💧 Fluid Transfer. Our pumps deliver high-efficiency performance, ensuring smooth, uninterrupted fluid transfer while meeting stringent GMP standards. With low maintenance requirements and seamless integration, they help maximize productivity and reduce downtime. 💡 Why choose Monoflo? 🔹 Durable Construction for harsh environments 🔹 Optimized Flow Rates for maximum efficiency 🔹 Fully Compliant with pharma-grade regulations 🔹 Minimal Energy Consumption Invest in a solution that guarantees safety, purity, and efficiency for your operations. 📞 Ready to learn more? Reach out today to see how the Monoflo Centrifugal Pump can improve your pharmaceutical manufacturing processes. 📢 Contact Us: 📞 +8801601323330 📧 aqua@aquabd.net #PharmaceuticalEngineering #CentrifugalPump #Monoflo #PharmaceuticalEquipment #WaterForInjection #PurifiedWater #CIPSIP #GMPCompliance #Biotech #PharmaProduction #PharmaInnovation #WaterTreatment #ProcessEngineering #FacilityManagement #Biopharma #SterileProcessing #ManufacturingExcellence #CleanTech #PharmaSolutions #OperationalEfficiency #SustainabilityInPharma #ProcessOptimization #Pump #PumpSupplier #PumpSystem #PumpSales #ChilledWaterPump #PipeLine #Engineering #Project #ProjectManagments #Factory #Utility #Pharma #Sales #SupplyChain #SupplyChainManagment #HVAC #PipeingSystem #PumpSupplier #Chiller #ChillerPiping #WaterTransfer #AquaTechnoTrade #BangladeshPharma

**MARKET APPLICATION - PHARMACEUTICAL INDUSTRY** In the pharmaceutical industry, liquid ring vacuum (LRV) pumps play a crucial role in various manufacturing processes. They are typically used for drying, evaporation, distillation, and filtration, among other applications. By creating a vacuum, they aid in the removal of unwanted gases, moisture, and contaminants, ensuring high-quality and safe production. For chemical applications necessitating PN 10 pressure rated vacuum equipment, Speck’s VHD liquid ring vacuum (LRV) pump range is the technology of choice. Its robust construction, coupled with O-ring static sealing, makes it the ideal solution for demanding chemical processes were standard PN 3 rated equipment is not sufficient. The technology can be supplied in both mechanically and hermetically sealed variants; the latter reserved for processes where 100% containment of the process gas / vapour is required. Utilization of PEEK and ceramic separating CANs ensure high chemical resistance and no eddy current losses. If you seek a premium, low maintenance product boasting high safety for your chemical plant, contact us at ‘pumpsales@speck-abc.com’. #speck #speckroth #pharmaceutics #industry #distributor