Helix Biostructures’ Post

Proud to share the collaborative work by my colleague Emily D. Melton, PhD, our Bioscience at IFF Lead Regulatory Scientist in Microbial Strain Safety, together with other industry experts: https://lnkd.in/gyT9AaXQ. This paper is a significant contribution supporting decision makers' ability to fully consider safe pathways for deliberate release of genetically engineered microbes (#GEMs), regardless of the current regulatory framework. Such full consideration of safe deployment of GEMs (aka #GMMs in the EU) would benefit applications such as: 👉 utilization of (currently wasted) spent fermentation #biomass, 👉 deployment of modern biotechnology in #cropbiologicals, 👉 advanced versions of #foodcultures and #probiotics for use in food, feed, and supplements. 👉 or simply to clean up (after) ourselves. The timing of this scientific publication is perfect in light of the EU discussions on Gene Editing / New Genomic Techniques (#NGTs) and stakeholder initiatives in both the EU and US to design better regulatory pathways for safe and effective deployment of engineered microbes. AMFEP FEFANA asbl EuropaBio - the European Association for Bioindustries #geneediting #newgenomictechniques #engineeredmicrobes

Interest continues to grow in using transgenic plants as a source of secondary metabolites. Genetic engineering technology has produced plant systems that are efficient at producing specific secondary metabolites or recombinant proteins. Published by MDPI, this journal article details how research has shown that embracing plant systems and the use of bioreactors enables production to be increased to industrial scales, quickly and cost-effectively. By taking plant-based production out of the field and into the factory, SAMABRIVA’s innovative technology offers a scalable and sustainable way to make high value #biomolecules. It’s an approach that’s already proving irresistible to the #pharmaceuticalindustry. https://lnkd.in/edw_a63X #biomanufacturing #bioprocessing #bioproduction #lifesciences

I’m thrilled to announce the publication of my first scientific article 🎉,titled “Oxidative deterioration of polypropylene by redox mediators and yeast expressing a fungal recombinant laccase”! In this study, we explored a novel method to accelerate the degradation of polypropylene (PP), one of the most recalcitrant polymers to biodegradation. By using redox mediators and a genetically modified yeast strain to produce a fungal laccase enzyme, we successfully induced oxidation on the PP surface. Our results showed significant structural modifications in the polymer, increasing its wettability and creating exfoliated regions that promote the breakdown of the PP film. A big thanks to my professor, Michele Maria Bianchi, and to all the other co-authors for their invaluable support!🙏 Read the full article here: [https://lnkd.in/d38tGtnz] #Biodegradation #Sustainability #ScientificResearch #Polymers #PlasticDegradation

HepG2 cells are continuing to thrive! On day 7, they received fresh medium and are expected to be ready for subculture tomorrow. But that's not all -- during a medium change on day 5, I saved the medium and seeded it into a new flask. To my pleasant surprise, HepG2 cells that were alive but floating in the saved medium, have now adhered and begun to grow in the new flask. Now, there are two flasks of seemingly healthy-growing hepatocytes! It's fascinating to consider what factors contributed to this success: - old supplier vs new supplier - standard culture flasks vs collagen-coated culture flasks - centrifuging out the DMSO vs diluting it out - medium change after 24 hours vs no medium change after 24 hours - no antibiotics vs antibiotics (I hope not!) Have you dealt with a mammalian cell line (or fungal, or bacterial) that should have been "textbook" but proved more challenging than you expected? #biochem #biochemistry #biochemical #biochemist #biochemists #BiochemistryResearch #CellCulture #HepG2 #insulin #InsulinResistance #InsulinSignaling #laboratory #labresearch #LaboratoryResearch #MammalianCellCulture #MetabolicBiochemistry #metabolism #research #science #stem

Syngenta is on the hunt for technologies or services to identify and characterize surface and integrated membrane proteins in insect midgut membranes that interact with insecticidal proteins. 🐛 Their goal is to screen for new leads and assess their mode of action efficiently and at high throughput. Key areas of interest include: - Membrane protein purification (with/without lipids) - Solubilized membrane protein preparations - High-throughput quantification of protein binding - Characterization of binding via lipids, sugars, and protein receptors Are you developing a novel method? Join us in this challenge! 👉 Submit Your Solutions: https://bit.ly/3xvOaHI #BiotechInnovation #ProteinResearch #InsectControl #Syngenta #AgriTech #OpenInnovation

Excited to share that I participated in a hands-on workshop on Protein Purification and Cell Culture! It was an incredible experience to deepen my understanding and skills in these essential biotechnological techniques. The workshop provided valuable insights and practical knowledge that will significantly enhance my research capabilities. #Faceprep #proteinpurification #cellculture #STEMculture #Biotechnology

🍄 𝗙𝘂𝗻𝗴𝗶-𝗯𝗮𝘀𝗲𝗱 𝗽𝗿𝗼𝘁𝗲𝗼𝗺𝗶𝗰𝘀 𝘄𝗶𝘁𝗵 𝗕𝗶𝗼𝗴𝗲𝗻𝗶𝘁𝘆! Fungi are essential in antibiotic production, organic matter decomposition, and symbiotic relationships with plants, animals, insects, and parasites. They produce intriguing proteins, like digestive enzymes for detergents, and play significant roles in industries such as food, detergent, and pharmaceuticals. Proteomics provides essential insights into fungal biology, aiding in the understanding and modulation of fermentation and recombinant protein production. Learn more about our fungi-based proteomics: https://lnkd.in/eDAni3Cx

Metagenomics which represents a powerful and versatile tool that continues to advance our understanding of microbial diversity, ecology, and function across different ecosystems and applications within the omics landscape.

❓ Michelle Ballabio asked me to present SUN bioscience's #Gri3D technology - here's the result! Watch the video, part of our 30 Seconds of series, to learn about readouts and downstream analyses on #Gri3D plates 📽️ 🧫

🔍 𝗘𝘅𝗽𝗹𝗼𝗿𝗶𝗻𝗴 𝗙𝘂𝗻𝗴𝗮𝗹 𝗣𝗿𝗼𝘁𝗲𝗼𝗺𝗶𝗰𝘀 𝗳𝗼𝗿 𝗕𝗶𝗼𝗹𝗼𝗴𝗶𝗰𝗮𝗹 𝗜𝗻𝘀𝗶𝗴𝗵𝘁𝘀 Fungi are crucial in various industries, from antibiotics production to bioactive compounds for food and pharmaceuticals. Their ability to decompose organic matter and live symbiotically with other organisms makes them fascinating subjects for research. However, understanding the complexities of fungal processes, such as mycotoxin production and fermentation, requires advanced proteomics. At Biogenity, we help you navigate the diverse opportunities and limitations of proteomics to answer your research questions. Explore how our expertise can enhance your understanding of fungal biology. Learn more: https://lnkd.in/eDAni3Cx