Hezha O. Rasul’s Post

Check out the latest research by Associate Prof. Zhifeng Du's team at Huazhong University of Science and Technology's School of Pharmacy, Tongji. Their article in the Journal of Inorganic Biochemistry unveils molecular targets of cisplatin in HeLa cells using a competitive activity-based protein profiling strategy. In this study, Chomix Biotech provided professional support for chemical proteomic sample preparation and mass spectrometry analysis in target discovery. We successfully identified 3571 peptides involving 1871 proteins, with 46 proteins identified as potential targets of cisplatin. In addition to chemical proteomic sample preparation and mass spectrometry analysis, Chomix‘s target identification service includes the identification of drug-protein binding sites, providing crucial support for elucidating drug mechanisms of action. Read on：https://lnkd.in/gZrM8Cyt #PharmaResearch #ProteinProfiling 🧪🔬

Did you know that DNA purification plays a crucial role in various scientific applications? 🧬✨ #knowledge #manufacture #DNAPurifications Discover the fascinating process of DNA purification and how it enables advancements in biotechnology and medical research.

🏆 First-Ranked Scientific Achievement Award in Advanced Medical Sciences and Technologies. If given a choice to return and pick a major again, I would happily go with Medical Biotechnology and Artificial Intelligence-Based Protein Engineering. #biotechnology #proteinengineering #artificialintelligence

I am happy to share the release of the "𝗛𝗮𝗻𝗱𝗯𝗼𝗼𝗸 𝗼𝗳 𝗠𝗼𝗹𝗲𝗰𝘂𝗹𝗮𝗿 𝗕𝗶𝗼𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆" published by 𝗖𝗥𝗖 𝗣𝗿𝗲𝘀𝘀, 𝗧𝗮𝘆𝗹𝗼𝗿 & 𝗙𝗿𝗮𝗻𝗰𝗶𝘀 𝗚𝗿𝗼𝘂𝗽. The first edition presents state-of-the-art reviews on DNA, RNA and protein technologies and discusses key strategies and experimental execution for their utility in biotechnology. Check out the chapter on 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗣𝘂𝗿𝗶𝗳𝗶𝗰𝗮𝘁𝗶𝗼𝗻 where we provide a brief perspective on the history of this process and examine the key principles underlying cell/tissue lysis and critical steps involved in the recovery of protein(s) of high quality and purity. The chapter ends with a detailed discussion of the utility of various purification protocols, emphasizing the repevance of the physicochemical properties of the target protein in determining the most appropriate purification technique. https://lnkd.in/e2xA_46u Thanks to coauthors Anupama Ghimire, Tam Pham, Jeffrey Simmons, and Qinyan Song and my PhD supervisor, Prof. Jan Rainey at Dalhousie University for providing me with this wonderful opportunity. #HandbookofMolecularBiotechnology #proteinbiochemistry #proteinpurification #gradschool

Molecular glues & proximity-inducing compounds: This historical perspective by Stuart Schreiber describes the field very well and shows the field has come full circle from molecular glues targeting native proteins, to bifunctionals targeting fusion proteins, and back to molecular glues and bifunctionals targeting native proteins. Modern screening methods and data analyses with pre-selected target proteins are shown to yield either cooperative molecular glues or bifunctional compounds that induce proximity, thereby enabling novel functional outcomes.  A fascinating field of drug discovery and, in particular, medicinal chemistry and mechanistic biochemistry. Paper: https://lnkd.in/e9CguthA Background reading: https://lnkd.in/eHfWKdWa https://lnkd.in/ejJN7JM2 https://lnkd.in/ecKTDDUe https://lnkd.in/euttayv5 https://lnkd.in/eAW-4-e2

Drug discovery bottlenecks got you down? Explore our collection of ready-to-use #primarycells for human microfluidics. Unlock the potential for faster, more efficient #drugdevelopment. Visit kosheeka.com to choose from our collection of primary cells for your #research. #cellculture #kosheeka #cellbiology #biochemistry #biomaterials #biomanufacturing #biomedicalresearch 

🌟 Unlock the Power of Molecular Interactions with Pronetbio! 🌟 We're excited to launch our new short video that explains the principles behind our Pull Down service! As a leader in yeast technology and molecular interaction research, ProNet Biotech (Nanjing Ruiyuan Biotechnology Co., Ltd.) specializes in providing innovative solutions for your scientific endeavors. With years of combined experience from our expert teams, we focus on cutting-edge services like Pull Down assays, enabling you to study molecular interactions with unparalleled efficiency. Our commitment to advancing biosynthesis and biotechnology is further demonstrated through collaborations with top-tier institutions. Whether you're exploring antibody discovery, enzyme engineering, or protein synthesis, our tailored services are designed to meet your research needs. ✨ Check out our video to learn more about the Pull Down principle and how it can benefit your research! For more information about our products and services, visit our website or reach out to us at info@pronetbio.com. Let's drive innovation together in the life sciences! https://lnkd.in/eaBXSkbu #ProNetBiotech #PullDown #RNAPullDown #MolecularInteractions #YeastTechnology #LifeSciences #RNAResearch

📢 A new Special Issue "Synthesis, Characterization, and Application of Biomacromolecules and Biobased Polymers" is now open for submissions! 🥼 This Special Issue is guest-edited by Dr. Shichao Ding and Dr. Wenzhuo Chen. 💡 Biomacromolecules and biobased polymers encompass a diverse range of large molecular substances found in biological organisms, including nucleic acids (polynucleotides), proteins (polypeptides), carbohydrates (glucans or polysaccharides) and lipids. This research is expanding their applications across diverse fields such as biopharmaceuticals, tissue engineering, biosensors, environmental protection, bioinformatics, bioengineering and materials science, representing a current research frontier. 🔗 Click the link to access more details about the Special Issue: https://lnkd.in/eqiyMFHZ. 🕑 The deadline for manuscript submissions is 20 December 2025. 🎉 We invite contributions to this focused Special Issue and encourage you to share this information with colleagues and peers who may be interested in this topic. 👏 And welcome to follow our LinkedIn account: https://lnkd.in/grPNkBrg. #biomacromolecules #biobased #polymers #synthesis #characterization #engineered #biomaterial #biopharmaceuticals

Advancing Genetic Engineering and Synthetic Biology with McGinty Equation (MEQ) and Quantum Time Flip Integration Project Description: Skywise.ai proposes a collaborative project with leading biotechnology companies and research institutions to integrate the McGinty Equation (MEQ) technology with advancements in genetic engineering and synthetic biology. This collaboration aims to develop innovative biotechnological solutions that leverage the principles of MEQ and quantum time flip to enhance genetic manipulation, synthetic organism design, and overall biological research. The project will focus on creating advanced genetic engineering models, optimizing synthetic biology techniques, and exploring commercial applications in the biotechnology sector.

I am glad to share our new article entitled, "Antimicrobial peptides: Source, application and recent developments" published in the “Process Biochemistry” Journal.  https://lnkd.in/gqgShRJS