HUMAN BRAIN EXPO’s Post

The Rockefeller University disclosed biological markers which are molecular markers and predictive of brain pathology and clinical status and/or outcome in Parkinson’s disease (PD). The invention provides genes, RNA and protein markers that are associated with, relevant to, or predictive of Parkinson’s disease (PD), Parkinson’s disease with dementia (PDD), Parkinson’s disease with dyskinesia or Parkinson’s disease duration. The present invention further provides methods, kits and markers for the identification and monitoring of disease and disease aspects in Parkinson’s patients and their application as markers and targets in and for evaluating, monitoring and treatment of Parkinson’s disease and relevant pathologies and conditions associated with or developing in Parkinson’s disease. https://buff.ly/3CN8C9r #mentalhealth #brain #health #wellness #humanity #psychology #healthybrain #happybrain #neuroscience #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry

🧠 Human Brain 🧠 💫 INVENTIONS 💫 Application Number 18578749 Inventor: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY An anti-human transferrin receptor antibody having improved blood-brain barrier permeability has a regulated binding affinity to the human transferrin receptor, and thus exhibits excellent blood-brain barrier permeability. Therefore, if the anti-human transferrin receptor antibody is used in a multi-specific antibody or an antibody-drug conjugate, proteins or drug compounds for treating brain diseases can be effectively delivered to brain tissues. 🧠 🧠 🧠 #mentalhealth #brain #health #wellness #humanity #neuroscience #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry

🧠 Human Brain 🧠 💫 INVENTIONS 💫 Application Number 18578749 Inventor: IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY An anti-human transferrin receptor antibody having improved blood-brain barrier permeability has a regulated binding affinity to the human transferrin receptor, and thus exhibits excellent blood-brain barrier permeability. Therefore, if the anti-human transferrin receptor antibody is used in a multi-specific antibody or an antibody-drug conjugate, proteins or drug compounds for treating brain diseases can be effectively delivered to brain tissues. 🧠 🧠 🧠 #mentalhealth #brain #health #wellness #humanity #neuroscience #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry

White matter aging and its impact on brain function Aging leads to significant changes in white matter, characterized by volume reduction, compromised structural integrity of myelinated axons, and increased white matter hyperintensities. These alterations are strongly associated with cognitive decline and neurological disorders. The deterioration of myelin and its reduced regenerative capacity further contribute to the progression of neurodegenerative diseases. Understanding these age-related changes is crucial for developing effective disease prevention strategies. This review, published in Neuron: https://lnkd.in/dYGQKGbt, explores the structural alterations in white matter that occur with aging and examines the cellular and molecular mechanisms driving these transformations. It highlights how the progressive disruption of white matter may initiate a self-perpetuating cycle of inflammation and neural damage. #genetics #genomics #precisionmedicine #genomicmedicine #brain #glia #lipids #neurology #neuroscience #neurodegeneration #neuroinflammation #aging #longevity #dementia #cognition #alzheimer #parkinson #biomarkers #therapeutics #drugdevelopment #biotechnology #innovation #research #science #sciencecommunication

🧠 New Insights into Parkinson’s Disease Dementia (PDD) and Dementia with Lewy Bodies (DLB) New study compares brain activity between PDD and DLB patients through advanced EEG analysis. By analyzing spectral and nonlinear dynamics, key differences in the power spectrum and cortical complexity were found: Key Findings: DLB patients showed more diffuse slowing and lower cortical complexity compared to PDD, particularly in central, temporal, and parietal regions. While both groups differed significantly from healthy controls, PDD showed greater power in the theta and alpha bands than DLB. These insights can contribute to more accurate diagnoses, targeted treatments, and better monitoring of dementia in patients. https://lnkd.in/gRJT-JDe https://lnkd.in/gsXEXRkJ #DementiaResearch #ParkinsonsDisease #LewyBodyDementia #Neuroscience #EEGAnalysis

Understanding Cerebral Venous Sinus Thrombosis #sciencefather #CerebralVenousSinusThrombosis Cerebral Venous Sinus Thrombosis (CVST) is a rare form of stroke that occurs when a blood clot forms in the brain's venous sinuses, preventing blood from draining out of the brain. This blockage can lead to increased intracranial pressure and possibly a hemorrhagic stroke. Symptoms of CVST include headache, blurred vision, seizures, and neurological deficits. It is often associated with conditions such as infection, trauma, pregnancy, or certain genetic disorders. Treatment typically involves anticoagulation therapy to prevent further clotting.  #CVST #StrokeAwareness #BrainHealth #Neuroscience #BloodClots #Neurology #MedicalResearch #RareDiseases #HealthAwareness #neuroscienceientist, #Geneticist, #Biostatistics, #microbiology #Immunologist, #Professor, #Lecturer, #scientists, #Scholar, #Researcher, #Sociologist, #Psychologist, #CognitiveScientist, #BehavioralScientist, #Linguist, #Criminologist, #ForensicScientist, #Archaeologist, #MuseumCurator, #Archivist, #LibraryScientist, #InformationScientist, #KnowledgeManager, #PatentExaminer #innovationmanager connect Here :---------------------------------------  visit our website: https://lnkd.in/gZ3Fkd3n   Nomination now: https://lnkd.in/ge9ucRRt

🧠 Human Brain Matters 🧠 🧠 Global Brain Health Innovations 🧠 EÖTVÖS LORÁND TUDOMÁNYEGYETEM invented a novel approach toward the vascular dementia diagnosis. Declining cerebral blood flow leads to chronic cerebral hypoperfusion which can induce neurodegenerative disorders, such as vascular dementia. The reduced energy supply of the brain impairs mitochondrial functions that could trigger further damaging cellular processes. Altered levels of protein biomarkers are discloses to be useful in the diagnosis of vascular dementia. https://buff.ly/3MvYIui Please, join us to protect and transfer your IP Elite Inventors Club https://buff.ly/4e1o2Em __ #mentalhealth #brain #health #wellness #humanity #neuroscience #medicine #longivity #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry #news #management

🧠 Human Brain Matters 🧠 🧠 Global Brain Health Innovations 🧠 EÖTVÖS LORÁND TUDOMÁNYEGYETEM invented a novel approach toward the vascular dementia diagnosis. Declining cerebral blood flow leads to chronic cerebral hypoperfusion which can induce neurodegenerative disorders, such as vascular dementia. The reduced energy supply of the brain impairs mitochondrial functions that could trigger further damaging cellular processes. Altered levels of protein biomarkers are discloses to be useful in the diagnosis of vascular dementia. https://buff.ly/3MvYIui Please, join us to protect and transfer your IP Elite Inventors Club https://buff.ly/4e1o2Em __ #mentalhealth #brain #health #wellness #humanity #neuroscience #medicine #longivity #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry #news #management

🧠 Human Brain Matters 🧠 🧠 Global Brain Health Innovations 🧠 Biomimetic nanovesicles (BNVs), including endogenous extracellular vesicles (EVs) derived from various cells and artificial nanovesicles, possess the ability to penetrate the BBB and thus can be utilized for drug delivery to the brain. BNVs, especially endogenous EVs, are widely distributed in body fluids and usually carry various disease-related signal molecules such as proteins, RNA, and DNA, and may also be analyzed to understand the etiology and pathogenesis of brain diseases. https://lnkd.in/dFdktRj3 __ #mentalhealth #brain #health #wellness #humanity #neuroscience #medicine #longivity #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry #news #management

🧠 Human Brain Matters 🧠 🧠 Global Brain Health Innovations 🧠 DUKE UNIVERSITY invented a modular RNA molecule that facilitates sensing and detection of a cell type or cell status of a cell, including a cell of a mammalian nervous system, such as a neurons and/or neuronal cells of the area postrema of the mammalian brain, and/or facilitates delivery of an effector protein to the selected cell. Publication Number WO/2024/137718 __ #mentalhealth #brain #health #wellness #humanity #neuroscience #medicine #longivity #HBE #humanbrainexpo #3hbrain #science #AI #brainhealth #ethics #helpfulbrain #innovation #innovationmanagement #events #news #biotech #psychiatry #news #management