The International Centre for Antimicrobial Resistance Solutions (ICARS)’s Post

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#ClimateChange is affecting human, animal, and environmental health, often contributing to the development of antimicrobial resistance (#AMR). 🌍 Shifts in environmental conditions are likely to increase the spread of diseases across humans, animals, and plants. Although the links between climate change, rising temperatures, infection spread, and AMR are complex and not yet fully understood, they pose a significant risk, particularly in Low- and Middle-Income Countries (#LMICs) where livestock and aquaculture systems are already vulnerable. 💡 To address this, The International Centre for Antimicrobial Resistance Solutions (ICARS) has launched a request for proposals for Intervention and Implementation Research Projects to mitigate these challenges. 📅 Proposals should be submitted by research organizations based in Low-and-Middle-Income Countries up until October 1, 2024. 🔗 More details ➡️ https://lnkd.in/evCCVk3Q

The Genomic Research and Development Initiative is tackling antimicrobial resistance through a One Health approach. 🌍 By working with federal departments and agencies, we’re identifying antimicrobial resistance hotspots and key points for action to limit its spread. This year, we proudly hosted the annual general meeting, which included research updates and a policy simulation to show how scientific data drives decision-making. 🧬 Discover how the CFIA is fighting antimicrobial resistance head-on: https://bit.ly/3ZhAn2y #AMR #OneHealth #WAAW #AnimalHealth Agriculture and Agri-Food Canada/ Agriculture et Agroalimentaire Canada Health Canada | Santé Canada Fisheries and Oceans Canada / Pêches et Océans Canada Environment and Climate Change Canada Public Health Agency of Canada | Agence de la santé publique du Canada

Antimicrobial resistance (AMR) is a public health threat to both humans and animals. AMR occurs when germs such as bacteria, viruses and parasites change over time and stop responding to current drug treatments. To address this problem, more than 30 experts across 6 Government of Canada departments are working on the AMR2 project, funded by the Genomics Research and Development Initiative. Through this project, the team is studying how AMR emerges and moves through healthcare, animals, plants, wastewater and the environment. Learn more about the project: https://ow.ly/EyR450UbRHz #GRDICanada #NRCHealth #AntimicrobialResistance #WAAW #AMR Agriculture and Agri-Food Canada/ Agriculture et Agroalimentaire Canada Canadian Food Inspection Agency Environment and Climate Change Canada Fisheries and Oceans Canada / Pêches et Océans Canada Health Canada | Santé Canada Public Health Agency of Canada | Agence de la santé publique du Canada

Where would we bee without our pollinators and honey makers? 🐝 These questions are at the heart of a number of Endeavour Smart Ideas projects looking at everything from optimising bee keeping practices to laser-eliminating varroa mite and using immunotherapy to combat deformed wing virus. This pic was taken during a tour of the lab at Victoria University of Wellington where Professor Phil Lester, Associate Professor Janet Pitman and their team are exploring how antibody therapy could be used to control viruses and varroa parasites in honey bees. Immunoglobulin antibodies have previously been developed to treat infections including influenza. They're cheap to produce, can be stored for long periods and leave no synthetic chemical residues in honey. The goal is to develop an environmentally safe, commercially viable method to control this pest and disease in honey bees. However, it could also become a model way to control many other pest species. 🍯 Discover more Endeavour-funded projects 👇 https://lnkd.in/eVXjTJCG #WorldBeeDay The New Zealand Institute for Plant and Food Research Limited Ministry for Primary Industries (MPI) Environmental Protection Authority NZ Ministry for the Environment | Manatū mō te Taiao Ministry of Business, Innovation and Employment

Sharing our latest publication that highlights importance of using a geospatially-informed One Health model to incorporate climate, food, animals, and people. Specific climates, camel-keeping practices, and food needs predicted where MERS-CoV occurred more often throughout Kenya. This diverse team of scientists not only grew our skills and insights, but together we were able to figure out the right factors that predict emerging infectious diseases. This type of collaborative work is necessary to predict and prevent the next pandemic. Sharon Deem Eric Fevre Ted Lawrence Geoffrey Kangogo, PhD james Brien SLU College for Public Health and Social Justice International Livestock Research Institute (ILRI) #geospatialhealth https://lnkd.in/gdnKjYUX

#Honeybees are essential to our food chain and play a crucial role in pollination. However they face serious threats. The bacterium 𝑃𝑎𝑒𝑛𝑖𝑏𝑎𝑐𝑖𝑙𝑙𝑢𝑠 𝑙𝑎𝑟𝑣𝑎𝑒, which causes #AmericanFoulbrood, is an example. Once this disease has taken hold, all the hives must be burned, resulting in significant losses. In an interview on the Porto Canal's Manhã Informativa program, CEB’s researcher Ana Oliveira presented the #Bee4Life Project, which aims to develop a quick and easy-to-use detection kit for rapid and early on-site assessment of bacterial infection in beehives. Researchers are currently preparing a #prototype of the innovation that will unquestionably impact both the ecosystem and agricultural practices. Watch the full interview (in Portuguese only).

🦠 Antimicrobial resistance is hitting the coasts In recent article, Jasmine Hagan discusses the rising threat of #AMR on humans, agriculture, and the environment. Focusing on coastal ecosystems, she illuminates the emerging hazards and technologies that could prevent calamity. 🌊 Coastal microbial communities face threats from sewage and wastewater, enhancing the spread of ARGs through mechanisms like horizontal gene transfer, raising urgent questions about the extent and methods of ARG proliferation in such environments. 🧫 Traditional culture-dependent methods fall short in revealing full microbial diversity, missing unculturable bacteria. Culture-independent methods like ProxiMeta can significantly enhance our understanding of microbial communities – including mobile genetic elements. 🔬 Studies using this technology trace ARGs to their hosts in complex environments – not only identifying ARG reservoirs, but tracking horizontal gene transfer, crucial for understanding antibiotic resistance spread and providing the blueprints for future efforts. 🌍 The World Health Organization's #OneHealth approach integrates human, animal, and environmental health strategies to combat AMR. By understanding environmental AMR, we can develop targeted strategies to mitigate the spread of drug resistance, offering hope for sustaining coastal and global health. 📚 Dive deeper into the fight against AMR in coastal ecosystems in Hagan’s article (link in comments).

I had the pleasure to join other experts to speak on the intersection between #AMR and #climatechange at an event organised by Ambassade de France en Thaïlande, Mahidol University, CIRAD, French Development Agency in South Asia and other partners. I spoke about the need to integrate AMR into global challenges like climate change, especially in the context of livestock and aquaculture systems in Low- and Middle-Income Countries (LMICs). The overlap between countries most vulnerable to climate change and those bearing the highest burden of AMR underscores the urgency of adopting climate-smart practices that simultaneously address AMR and enhance the resilience of these vital agri-food systems.

Climate change and AMR are among the top 10 major global health threats of our time. Addressing the complex commonalities of climate change and AMR through deep investment in an integrated One Health approach is necessary to jointly tackle these global public health issues. Meet Dr Nathalie Hilmi, a researcher of environmental economics from the Monaco Scientific Center who advocates for a One Health approach to control AMR. “Antimicrobial resistance (#AMR) in aquaculture poses significant threats to human health, the environment and the economy” says Dr Hilmi. “Resistant pathogens can be transmitted to humans via contaminated fish or water, leading to infections that are difficult to treat. Environmental impacts of #AMR include disruption of microbial communities and the spread of resistant bacteria to natural water bodies, which can re-enter the human food chain. From an economic perspective, resistant infections increase treatment costs and decrease productivity, potentially leading to significant losses and trade restrictions.” “To address #AMR, prudent use of veterinary medicines by fish farmers is essential. Improved regulatory frameworks, enforcement, and health support services can facilitate responsible antibiotic use, thereby mitigating #AMR. Good aquaculture practices, vaccinations, and alternatives, like bacteriophages, probiotics, and bioremediation, are effective in preventing infections and reducing the need for antibiotic use. Strategies to combat #AMR in the environment include better management practices, biosecurity measures, regulation enforcement and investment in research & development. Implementing these strategies requires a multifaceted "One Health" approach to ensure safety and sustainability in aquaculture.” #WHOEuro is sharing #Stories_of_AMR throughout the year, from countries across the European Region to raise awareness about the serious impact of #AMR. Let’s prevent #AMR together. #AMRAwareness; #onehealth; #saveantibiotics; #handlewithcare; #HealthForAll