Impact Network - Healthcare Research’s Post

Early Risk Factors for Alzheimer's Scientists find an association between spatial navigation struggles with increased dementia risk, noticeable 25 years before diagnosis. The data shows that frailty is not only a consequence of undetected dementia but contributes to its onset, accelerating in the 9 years before those who got dementia at the end of the study were diagnosed. Understanding the connection between ageing, frailty + dementia can provide useful targeted intervention strategies to reduce risk + improve the quality of life. Read more: https://lnkd.in/gFip-Mqs

Trying to explain the whole spectrum of dementia is quite daunting but necessary. Without the fundamental understanding of the disease it will always be challenging to find solutions. I have accepted that my role is to build a framework that allows research to grow and provide more answers. When you see the early manifestations of specific types of dementia it highlights the diagnostic challenges. One patient had a 2 year history of speech difficulties with no evidence of any major abnormality on radiology scans. The association of memory problems, receptive and expressive language difficulties made the diagnosis of Primary Progressive Aphasia highly probable. This is not a common cause of dementia. These early manifestations identify which part of the brain is most affected early in the disease, but eventually dementia becomes the predominant symptom. This fits with the theory that dementia has a primary pathology which will be able to explain all the forms that we see. Will do my best to explain it all in time. #dementia #alzheimers #endalz #research #brainhealth

🌎 The World Health Organization Blueprint for Dementia Research is a collaborative global effort to accelerate dementia research, improve care, and advance prevention. It outlines key themes and milestones to tackle dementia’s most urgent challenges through research, innovation, and partnership. Whether you're a researcher, policymaker, healthcare leader, funder or person with lived experience, the Blueprint is a call to action to make a difference. Join us in building a future of effective, equitable dementia and brain health research! 🔗 https://lnkd.in/dGmMZHex #WHODementiaBlueprint #DementiaResearch #BlueprintInAction Devora Kestel Rodrigo Cataldi Ishtar Govia Laura García Primrose Nyamayaro Vasee Moorthy Jasmine Vergara Cassie Redlich Renato Oliveira e Souza Ledia Lazëri Chido Rwafa- Madzvamutse Perminder Sachdev Alzheimer's Disease International World Dementia Council Alzheimer Europe Gates Ventures Dementia Alliance International Global Global Brain Health Institute (GBHI) European Brain Council World Federation Of Neurology European Academy of Neurology OneNeurology

An incredible collaborative global effort from the World Health Organization. This Blueprint had major input from researchers at CHeBA, led by Scientia Professor Perminder Sachdev, and emphasizes equity, diversity, and inclusiveness at all stages.

This is one of the most important pieces of research that I have come across. As we strive to find early markers for dementia, we may not yet have seen the full significance of this early radiological sign. The fact that brain atrophy is so intricately associated with dementia is very relevant. Brain atrophy is the same to dementia as glucose in the urine is to diabetes. They are markers of the disease that are visible at an early stage on a brain scan and urine dip, respectively. Looking at brain scans is a regular part of my job. My observation has been that brain atrophy is a good predictor of dementia. The brain of a person with mild cognitive impairment (MCI) or dementia appears shrunken and does not fill the skull cavity. The older patients who do not have brain atrophy are as sharp mentally as ever. It is fascinating to see the correlation as these patients seem to have a low probability for getting dementia. The question is why? We plan to discuss more topics like this. Follow us on LinkedIn or Like our Facebook page to keep updated. #dementia #alzheimers #endalz #research #brainhealth

Approximately 50 million people worldwide live with Alzheimer's or other related forms of dementia. Alzheimer’s disease leads to memory loss and impairment in cognitive function, and is the most common cause of dementia among older adults.   Researchers from Tel Aviv University have discovered that hyperbaric oxygen therapy (HBOT) can help with reversing the precursors of the disease.   Using hyperbaric oxygen therapy (HBOT), where a person breathes near-pure oxygen in a pressurised chamber, the researchers were able to repair damaged brain tissue associated with the biological hallmarks of Alzheimer’s, as well as renewing growth of blood vessels and nerve cells in the brain. The study showed that after a series of HBOT treatments, elderly patients who were already suffering from memory loss showed an improvement of blood flow to the brain as well as a real improvement in cognitive performance.
 Read more about this innovative study on our website: https://buff.ly/4dVa87u #hyperbaricoxygentherapy #alzheimers #dementiasupport #alzheimersdisease

Personality predictors of dementia diagnosis and neuropathological burden: An individual participant data meta‐analysis #alzheimers #neuropsychology

🧠🌍 Today, on World Brain Day, we're spotlighting the urgent need for Alzheimer's prevention. In conjunction with the World Health Organization, the World Federation Of Neurology has announced #BrainHealthandPrevention as this year’s theme. Despite decades of research, no 'silver-bullet' drug exists to treat Alzheimer's, the leading cause of dementia. The focus is shifting towards delaying onset through modifiable risk factors. We are leading the world’s largest online trial, "Maintain Your Brain", targeting 6000+ participants aged 55-77. Led by Professor Henry Brodaty AO, this innovative trial aims to slow cognitive decline and delay dementia through lifestyle changes. “Postponing onset by even two years could reduce Alzheimer’s disease prevalence by up to 20% and a 5-year delay could potentially halve the prevalence” said CHeBA Co-Directors Professors Brodaty and Professor Perminder Sachdev. With dementia being a major cause of disability and mortality, prevention is crucial. 🔗 Read more https://lnkd.in/gqSmP_92 #WorldBrainDay #Alzheimer #BrainHealth #CHeBA #MaintanYourBrain #WBD2024 UNSW UNSW Medicine & Health

New research from Linus Health confirms that early detection of Alzheimer's disease and cognitive impairment is critical to improving the healthcare trajectories of aging adults, enabling early intervention and potential prevention of decline. Published in Alzheimer's Association®’s Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring (DADM) Journal, researchers evaluated  multimodal feature sets for assessing memory impairment. The research revealed that incorporating graphomotor, memory, and speech and voice features provided stronger classification performance. This study adds to the understanding of the multimodal profile of individuals with cognitive impairment, indicating that their speech tends to be slower, with noticeable effects on the duration, frequency, and percentage of pauses compared to normal, healthy speech. https://lnkd.in/enp4Fcrv I #AlzheimersDisease #AlzheimersResearch #BrainHealth #CognitiveDecline #MildCognitiveImpairment Ali Jannati, MD, PhD David Bates Sean Tobyne Alvaro Pascual-Leone

Today, we raise awareness and support for the fight against dementia. Did you know dementia is one of the biggest challenges we face, with nearly 50 million people living with dementia worldwide? - https://hubs.li/Q02QpyDP0 At Veristat, in the past 5 years, we've partnered with 25 sponsors developing therapies to treat Alzheimer's Disease and its symptoms. Find out more about how we can support your neurology needs: https://lnkd.in/gYR5TBHn #WorldAlzheimersDay #Dementia #Alzheimers