British Society for Integrative Oncology’s Post

Hi everyone! I'm Thrilled to announce the publication of my first research article in the esteemed Journal of Probiotics and Antimicrobial Proteins! I personally loved working with this great team, Specially my good friend and classmate Dr. Sadeghi. Here is the the title and abstract of this article: "Efficacy of Probiotics in Overweight and Obesity Control: An Umbrella Review and Subgroup Meta-Analysis" https://lnkd.in/dZPf8KUa Abstract ـــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــــ Numerous primary and secondary studies have consistently demonstrated that probiotics, including lactobacillus and Bifidobacterium, possess a potential anti-obesity effect. However, it is worth noting that some studies have yielded contrasting results. Considering this, our study aims to present a comprehensive overview of published systematic reviews and meta-analyses, focusing on the efficacy and safety of probiotics in managing obesity. To achieve this objective, we conducted an umbrella review following the PRISMA protocol and Cochrane guidelines. We searched databases such as Embase, PubMed, Cochrane Library, and Google Scholar for relevant systematic reviews and meta-analyses published in English, without imposing any date restrictions. Our inclusion criteria encompassed studies evaluating the anti-obesity impact of probiotics, with a specific focus on changes in body mass index (BMI), fat mass percentage (FMP), body weight (BW), and body fat mass (BFM). These studies were meticulously reviewed by two independent reviewers. Our analysis included five systematic reviews and 18 meta-analyses that met the predefined inclusion and exclusion criteria. The meta-analyses revealed statistically significant reductions in the following parameters: BMI, a decrease of 0.30 kg/m2 (p < 0.00001, 95% CI − 0.36 to − 0.25); BFM, a reduction of 0.86 kg (p < 0.00001, 95% CI − 1.02 to − 0.71); BW, a decrease of 0.59 kg (p < 0.00001, 95% CI − 0.74 to − 0.44); and FMP, a substantial decline of 78% (p < 0.00001, 95% CI − 1.02 to − 0.54). In summary, our umbrella review suggests that existing evidence supports the potential benefits of probiotics in managing obesity and overweight. However, it is essential to acknowledge that the credibility of this evidence is somewhat limited due to the inclusion of studies with poor-quality designs and relatively small participant numbers. To establish the true efficacy of probiotics in obesity management, we recommend conducting robust studies involving larger participant cohorts. #probiotics #obesity #weightloss #research #nutrition #firstpublication

Functional Medicine is rooted in the principle of INCREASING & SUPPORTING the cellular processes of the body. Essentially, to restore function of all aspects of health via individualized nutrition, customized supplementation and lifestyle modifications. Needless to say, Functional Medicine is not for everyone as only patients who are willing to implement these changes will succeed through the functional approach. Unlike the Western medicine system where there is a pill or surgical band-aid solution to your symptoms, Functional Medicine works on the premise that you create the health you desire through daily habits and new behavioral patterns that make cellular changes. ANd let’s be honest, not everyone is ready or willing to “put in the work” to express functional health. But more on this another time. The Western Medicine approach is one that enables poor lifestyle choices with their synthetic pharmaceuticals and surgical approach to address symptoms. Most pharmaceuticals work by blocking or suppressing biochemical function of the body. The intention is NOT to improve function but rather to sedate and numb symptoms. Standard blood work and physical examination is merely tracking for catastrophic out of range values. This only allows for finding chronic disease at the end stages, giving minimal hope for change to occur. And the patient jumps on to the poly-pharmacy merry-go-round, starting them on a variety of pharmaceuticals, each suppressing different symptoms and biomarkers. If the patient is lucky (and has strong will), some lifestyle and nutritional changes can make a small impact at this stage. In cases where no diagnosis is made OR no biomarkers appear to be out of range, a pharmaceutical is still prescribed to address the symptom without any REAL objective physiological measure. And of course, this pharmaceutical is intended to block biochemical function in the body to suppress the symptom. Functional Medicine looks at the holistic picture of what the person is expressing, connecting the through line between symptoms, lifestyle, behaviors and beliefs. The functional medicine process is based on supporting physiological function - to upregulate, activate and repair function. The individualized and personalized approach of this medicine, recognized that rarely ever is there only 1 physiological imbalance responsible for any expressed symptom. That is to say, the same symptoms can have a number of different root causes - there is no one size fits all. Functional Medicine is an upstream approach to healing, following the thread from symptom to biomarker,to behavioral pattern, to patient history. Getting functional with your health means to unwind the tapestry of your being and weave a new tapestry from biology to beliefs. Ready to start addressing the physical symptoms of anxiety, stress & trauma? Comment the word RESTORE Xx Dr. Maritza

""Prevention is cheaper than cure!" Understanding Blood Cancer and the Benefits of Herbal Teas in Its Management “Discover how herbal teas like green tea, turmeric tea, and ginger tea can support blood cancer treatment by boosting immunity and reducing inflammation naturally.” Introduction Blood cancer, also known as hematologic cancer, affects the production and function of blood cells, impairing the body’s ability to fight infections, transport oxygen, and control bleeding. Common types include leukemia, lymphoma, and myeloma. This article will delve into the role of herbal teas in promoting overall well-being, emphasizing their antioxidant and anti-inflammatory properties, which can complement medical treatments. What Is Blood Cancer? Blood cancer originates in the bone marrow, where blood is produced. It disrupts the production of red blood cells, white blood cells, and platelets. Key types include: Leukemia: Affects white blood cells, leading to abnormal production. Lymphoma: Targets the lymphatic system, weakening immunity. Myeloma: Impacts plasma cells, reducing the body’s ability to produce antibodies. Symptoms of Blood Cancer Persistent fatigue Unexplained weight loss Frequent infections Excessive bruising or bleeding Swollen lymph nodes Conventional Treatments Treatments such as chemotherapy, radiation, and stem cell transplants are common. However, incorporating lifestyle changes, including the use of herbal teas, may support the body during treatment. Herbal Teas and Their Benefits for Blood Cancer Patients 1. Green Tea: A Powerhouse of Antioxidants Green tea is rich in polyphenols and catechins, which may help combat oxidative stress—a key factor in cancer progression. Benefits: Enhances immune function. Inhibits the growth of cancer cells. Reduces inflammation. Usage: Drink 2-3 cups daily to harness its potential benefits. 2. Turmeric Tea: Nature’s Anti-Inflammatory Agent Turmeric contains curcumin, a compound with potent anti-inflammatory and anticancer properties. Benefits: May reduce tumor growth. Alleviates chemotherapy-induced inflammation. Usage: Brew with black pepper to enhance absorption. 3. Ginger Tea: For Nausea and Inflammation Ginger is well-known for its ability to reduce nausea—a common side effect of chemotherapy. Benefits: Fights oxidative stress. Reduces fatigue and digestive discomfort. Usage: Drink before meals to ease digestion. Please, continue reading on: https://lnkd.in/g87qT-jj

🌿✨ Exploring the Chemistry and Health Benefits of Turmeric ✨🌿 Turmeric (Curcuma longa), a vibrant rhizome from the ginger family, boasts a rich chemistry centered around curcumin. This polyphenol gives turmeric its characteristic yellow hue and comprises a complex structure of aromatic ring systems linked by conjugated double bonds and O-methoxy phenolic groups. Chemical Features: 🌿 Polyphenolic Nature: Curcumin belongs to the polyphenol group, characterized by phenolic hydroxyl groups that contribute to its antioxidant properties. 🌿 Conjugated Double Bonds: These bonds create a system of alternating single and double bonds along the carbon chain, influencing its stability and reactivity. 🌿 Functional Groups: The presence of methoxy and hydroxyl groups enhances curcumin's solubility and interactions with biological molecules. Health Benefits: 🔹 Anti-inflammatory Properties: Curcumin aids in reducing chronic inflammation, potentially benefiting conditions like arthritis and metabolic syndrome. 🔹 Antioxidant Effects: It neutralizes free radicals and boosts the body’s own antioxidant defenses, safeguarding cells from damage. 🔹 Improved Brain Function: By supporting the growth of neurons, curcumin may enhance brain-derived neurotrophic factor (BDNF) levels, potentially lowering the risk of neurodegenerative diseases. 🔹 Heart Health: Curcumin enhances endothelial function and combats inflammation and oxidation crucial in heart disease prevention. 🔹 Anti-cancer Potential: It affects cancer at the molecular level, inhibiting growth and metastasis while promoting cancer cell death. 🔹 Management of Depression: Curcumin shows promise in alleviating depression symptoms, influencing BDNF levels and neurotransmitter regulation. 🔹 Arthritis Relief: Its potent anti-inflammatory properties can help manage arthritis symptoms effectively. 🔹 Digestive Health: Turmeric supports digestion and has been a staple in traditional medicine for treating digestive disorders. Safety Considerations: While generally safe at low doses, high doses of curcumin can lead to gastrointestinal issues, may also impact liver function, and may interact with medications. Consulting a healthcare provider before starting supplements, especially in higher doses or with underlying health conditions, is recommended. Incorporating turmeric into your diet—whether through cooking or supplements—can offer numerous health benefits. To enhance curcumin absorption, pairing it with black pepper (containing piperine) is often advised due to curcumin's relatively low bioavailability. #Turmeric #HealthBenefits #NaturalRemedies #Nutrition #Wellness #Biochemistry

We Must Rethink Cholesterol. We Probably Owe it an Apology. For years, we've been told that high cholesterol is the primary culprit behind heart problems, leading to aggressive treatments with statin drugs. However, as a naturopath, I've long held a different view – one that's FINALLY gaining traction in some medical circles. Contrary to popular belief, the cholesterol plaque in our arteries might actually be part of our body's immune response – a protective mechanism rather than the root cause of heart disease. This challenges the conventional wisdom that has dominated healthcare for decades. Recent research has cast doubt on the direct link between elevated cholesterol and cardiovascular disease. Some studies suggest that lower cholesterol levels might increase the risk of death from other causes. This revelation begs the question: Have we been focusing on the wrong target? An alternative model proposes that atherosclerotic lesions – the hallmark of heart disease – are actually the result of the body's healing process. According to this theory, blood clots form to repair arterial damage, and these healed areas create the characteristic plaques. The evidence supporting this model appears more robust than the traditional cholesterol hypothesis! Despite these findings, the medical industry has largely continued to push cholesterol-lowering statin drugs as the primary treatment for heart disease. The statin market has ballooned, yet the benefits are minimal. Some analyses suggest that years of statin use might extend life by only days, while the potential side effects can be severe. What's often overlooked is the vital role cholesterol plays in our body's functions. Cholesterol is not just a potential risk – it's an essential component. It forms a crucial part of our cell membranes, providing stability and regulating what enters and exits our cells. Cholesterol is particularly important for brain health and function. Our brains contain about 25% of all the cholesterol in our bodies, despite making up only 2% of our total weight. This cholesterol is vital for the formation of synapses – the connections between brain cells that allow for thought, memory, and learning. As a naturopath, I advocate for a holistic approach to heart health. Instead of relying solely on pharmaceuticals, we should focus on the foundations of good health – primarily, a nutrient-rich diet. Eggs and red meat aren't the enemy. High-quality animal proteins have played a crucial role in human evolution and can be part of a heart-healthy diet. A truly heart-supportive diet should be high in fiber and include a variety of plant foods (if well-tolerated), along with high-quality meats. Equally important is the avoidance of ultra-processed foods, refined sugars, and poor-quality oils. Let's work towards a more balanced and holistic approach to health. #hearthealth #cardiovasculardisease #naturopathy #holistichealth #nutrition #nutritionalmedicine

BENEFITS OF MORINGA WHICH IS ALSO KNOWN AS MAGIC TREE Antioxidant and Anti-Inflammatory Properties Moringa leaves are rich in antioxidants, including vitamins C and E, beta-carotene, and other polyphenols. These antioxidants help protect the body against free radicals, which can cause cell damage. Studies have shown that moringa leaves have a high antioxidant capacity, which can help reduce oxidative stress and inflammation in the body (Kumar et al., 2018). The anti-inflammatory effects are thought to be due to the presence of compounds such as isothiocyanates, which have been shown to inhibit the production of pro-inflammatory cytokines (Singh et al., 2019). Cardiovascular Health They have been found to have a positive effect on cardiovascular health by reducing blood pressure, cholesterol levels, and triglycerides, help reduce the risk of heart disease, stroke, and other cardiovascular conditions. (Gupta et al., 2020). Antidiabetic Properties They have been found to have antidiabetic properties, which can help regulate blood sugar levels and improve insulin sensitivity. (Kumar et al., 2019). Antimicrobial Properties The antimicrobial effects of moringa leaves are thought to be due to the presence of compounds such as isothiocyanates, which have been shown to inhibit the growth of microorganisms (Singh et al., 2020). Cancer Prevention The antioxidants and other compounds present in moringa leaves have been found to have anti-cancer properties, moringa leaves can help inhibit the growth of cancer cells and induce apoptosis (cell death) in various types of cancer, including breast, colon, and prostate cancer (Kumar et al., 2018). Neuroprotective Effects They have been found to have neuroprotective effects(are thought to be due to the presence of compounds such as antioxidants and anti-inflammatory agents, which can help reduce oxidative stress and inflammation in the brain), which can help protect against neurodegenerative diseases such as Alzheimer's and Parkinson's. (Singh et al., 2019). Digestive Health They have been found to have prebiotic properties, which can help promote the growth of beneficial gut bacteria and improve digestive health. Studies have shown that moringa leaves can help improve gut health and reduce symptoms of irritable bowel syndrome (IBS) (Kumar et al., 2020). Immune System Support They have been found to have immunomodulatory effects, which can help stimulate the immune system and increase the production of antibodies (Singh et al., 2020). Bone Health Studies have shown that moringa leaves can help improve bone density and reduce the risk of osteoporosis (Gupta et al., 2020). Menstrual Health Moringa leaves have been found to have antispasmodic and anti-inflammatory properties, which can help alleviate symptoms associated with menstrual cramps and other menstrual disorders. (Kumar et al., 2019). #womenhealth #Healthcare #NutritionAndWellness #HealthyLiving #FoodScience #Moringa #MoringaLeaves #HealthBenefits #Nutrition

I'm delighted to share the news that I have been awarded a Fellowship of the British Association for Nutrition and Lifestyle Medicine. For those who don't know my story, a mid life breast cancer diagnosis in 1997 prompted radical career change. I started my working life in 1986 with a degree from University of Manchester in Management Sciences and became a partner in a small management consultancy, working from a Thames Sailing Barge moored by Tower Bridge. But the cut and thrust of financial services was not my comfort zone. After my diagnosis, I went back to college and graduated with distinction from ION in 2004, setting up my practice and joining the ION academic team. While there, I redesigned the clinical programme and nutrition questionnaire, mastered Krebs cycle sufficiently to deliver the metabolism lecture in 2009, and delivered their first cancer support workshop. During those early years of practice I was emotionally and academically unprepared to work with breast cancer patients but continued to develop my knowledge while supporting a generalised client base. In 2009 I started a professional blog and, in 2012, was the first UK nutritional therapist to publish a book on the benefits of the ketogenic diet, The Dissident Diet. With the emergence of nutrigenomics and the revival of the Warburg theory I felt there was enough evidence to place nutritional therapy front and centre for breast cancer. Thus, in 2016, I decided to add to my skills, completing AFMCP and joining the MSc programme at CNELM. While I relished the challenge, clinic was busy and I felt my time (and my heart) was more usefully engaged working with clients. Thus I cut short my studies and graduated with a PG Cert in 2017 and a passion for nutrigenomics. My first speaking engagement, for BANT SE Region, was in 2017 presenting ‘Beyond BRCA’, looking at the relevance of single nucleotide polymorphisms in breast cancer. This was a pioneering talk and the foundation for many invitations to speak to professional audiences. There followed a period of intense self-directed and lonely learning as I attempted to design personalised breast cancer protocols for women in need of support, working long hours to understand and communicate the relevance of nutrition for breast cancer, sharing my knowledge with clients and practitioners alike. As an individual and as a practitioner I am driven by the need to empower healthy choices; I take my responsibility to clients and the good name of my profession very seriously, while I’m not afraid to push the boundaries of what is considered to be within our scope of practice. In 2023 I started to write a weekly Substack blog to share my specialist knowledge with a wider audience of breast cancer patients and I'm happy to say this has become a bestselling blog. I'd like to thank BANT for all their tireless work behind the scenes in representing our profession and for recognising my work and my mission.

Really good post and the ANSWERS are in personalization of diet and supplementation. You are built to eat three different things (as evidenced by the type of enzymes your pancreas will make and release). Fats, proteins (glued together amino acids), and carbs. While we are just beginning to understand inputs, if you are looking at nutrition it is VERY IMPORTANT to understand what is important to your body/system and what is not. FATS are the most consequential and important things to your body. Your input of saturated/mono/poly sets a TONE in your body of inflammation and a sensitivity switch. Right now we are super sensitive and will INFLAME as a reaction due to our horrible misbalance of O3:O6 ratio. Further, FATS are what produce endocannabinoids which are our master regulators and front line immune starters. We CANNOT achieve our healthiest selves without understand the consequences and benefits of BALANCING and MANAGING our fat intake. In managing obesity now we have another consideration which is the microbiome. Obesity is NOT A NATURAL STATE = God did not engineer anyone to be obese. Obesity can occur through several mechanisms. The most prevalent is an overgrowth of certain microbiome bacteria. These bacteria can HIJACK THE SATIETY SYSTEM and do (how they do is fascinating...). In obesity endocannabinoids are elevated. This is due to a lack of control due to the signaling of adipose tissues that they are full and good, but broken mechanism in the gut due to bacteria. Over eating FAVORS THE PATHOGEN, not you. The Endocannabinoid system, as our master control system, is what builds and manages the SATIETY molecule called oleamide. Oleamide CONTROLS GLP-1 and GIP (and peptide YY and many other satiety molecules) through its interactions with GPR119. I am building a DRUG here and hope to have that available soon. We have already built a natural product which work well and you can find that as FAST TrueMedX Bioceuticals . Fast is safe and effective. Our drug will be even better.

Exploring the Role of Apigenin and Rutaecarpine in Osteoporosis Prevention In the quest for natural treatments for osteoporosis, two compounds, apigenin and rutaecarpine, have shown promising potential. Osteoporosis, characterized by decreased bone density and increased fracture risk, affects millions worldwide, particularly postmenopausal women. While traditional treatments focus on calcium and vitamin D supplementation along with pharmaceuticals, natural alternatives like apigenin and rutaecarpine offer complementary approaches. Apigenin, a flavonoid found abundantly in foods like parsley, celery, and chamomile tea, has demonstrated significant benefits in bone health. Research suggests that apigenin enhances bone mineralization by influencing osteoblasts, the cells responsible for bone formation. A study published in the "Journal of Cellular Biochemistry" noted that apigenin promotes the growth and activity of osteoblasts, which are crucial for maintaining and improving bone density (Zhang et al., 2009). Moreover, apigenin's anti-inflammatory properties contribute to its effectiveness in bone health. Inflammation is a known factor in many chronic conditions, including osteoporosis. By modulating inflammatory pathways, apigenin helps in preventing bone loss associated with chronic inflammation. Rutaecarpine, an alkaloid from the Evodia rutaecarpa plant, used in traditional Chinese medicine, also shows promise in osteoporosis prevention. This compound has been studied for its effects on bone metabolism. According to a study in the "International Journal of Molecular Sciences," rutaecarpine exhibits potential to inhibit osteoclastogenesis—the process of bone resorption—thus aiding in maintaining bone density (Kim et al., 2015). Rutaecarpine’s mechanism involves the modulation of signaling pathways that regulate osteoclast differentiation and activity. By inhibiting these processes, rutaecarpine reduces bone breakdown, which is vital in managing and preventing osteoporosis. Practical Applications and Considerations For individuals seeking natural methods to complement traditional osteoporosis treatments, incorporating foods rich in apigenin and considering supplements like rutaecarpine could be beneficial. Regular consumption of apigenin-rich foods, like a daily cup of chamomile tea or adding parsley and celery to meals, can be simple dietary adjustments. However, rutaecarpine, being less commonly found in dietary sources, might be considered in supplement form, under professional guidance. Before starting any new treatment, consulting with a healthcare provider is crucial, especially for those with existing health conditions or who are taking other medications. The integration of these compounds into a treatment regimen should be done cautiously to ensure it aligns with one’s individual health needs and conditions.

Did you know that cinnamon is a spice rich in antioxidants and associated with numerous health benefits? While not traditionally classified as an adaptogen, cinnamon may support various bodily functions by helping the body maintain balance. For instance, it can assist in regulating blood sugar levels and may promote both increased energy and relaxation when needed. Polyphenols, the micronutrients abundant in cinnamon, are responsible for its potent antioxidant activity. These compounds help protect the body against oxidative stress, which can slow down the aging process and promote longevity. Cinnamon contains anti-inflammatory compounds that may serve as natural alternatives to non-steroidal anti-inflammatory drugs (NSAIDs). By reducing inflammation, it may help alleviate issues associated with chronic inflammation. Studies have shown that cinnamon can improve key risk factors for heart disease by lowering levels of total cholesterol, triglycerides, and blood pressure. Additionally, certain compounds in cinnamon, such as cinnamaldehyde and epicatechin, appear to inhibit the accumulation of tau protein in the brain—a hallmark of Alzheimer’s disease. In animal studies, cinnamon has demonstrated neuroprotective effects in models of Parkinson’s disease by protecting neurons, normalizing neurotransmitter levels, and improving motor function. Cinnamon may also exhibit anti-cancer properties. It has been observed to reduce the growth of cancer cells, inhibit angiogenesis (the formation of new blood vessels in tumors), and induce apoptosis (programmed cell death) in cancer cells. In studies involving mice with colon cancer, cinnamon activated detoxifying enzymes in the colon, potentially protecting against further cancer growth. Cinnamaldehyde, a major component of cinnamon, possesses antifungal and antibacterial properties. These may help reduce infections, combat tooth decay, and alleviate bad breath. Some studies suggest that cinnamon extracts might help fight HIV-1, the most common strain of the human immunodeficiency virus. It is important to note that the Cassia variety of cinnamon contains significant amounts of coumarin, a compound that can be harmful in large doses. While all types of cinnamon offer health benefits, excessive consumption of Cassia cinnamon may pose health risks due to its coumarin content. Ceylon cinnamon, also known as “true” cinnamon, contains much lower levels of coumarin and is considered a safer option for regular use. www.ehcsport.com