The Jackson Laboratory’s Post

🚨 In a groundbreaking development in cancer research, Cancer Research UK,Cell Genomics @CellGenomics, has unveiled a pivotal study that challenges the notion of prostate cancer as a singular disease. Utilizing the power of artificial intelligence, researchers have delved deep into the intricate complexities of prostate cancer, revealing a spectrum of variations that demand personalized approaches to treatment. This significant breakthrough marks a paradigm shift in our understanding of the disease, offering new insights into its diverse manifestations and paving the way for tailored treatment strategies. This revelation underscores the importance of harnessing cutting-edge technology to decode the intricacies of cancer biology and develop targeted interventions that address the unique characteristics of each patient's cancer. By recognizing that prostate cancer is not a uniform entity but rather a spectrum of distinct subtypes, researchers are poised to revolutionize how we approach diagnosis, prognosis, and treatment decisions. However, amidst this groundbreaking discovery, it's crucial not to overlook the critical role of early detection. Men, heed the call: prioritize regular check-ups and screenings. Early detection remains our most potent weapon in the fight against prostate cancer, offering the best chance for successful treatment outcomes and improved survival rates. Let's unite in the battle against cancer and ensure that every individual receives the care and support they need to thrive. @NDSurgicalSci, Nuffield Department of Surgical Sciences at the University of Oxford https://buff.ly/3T2Mkoi

Over the last two years, the Cancer Bioengineering Initiative (CBI) has become a three-grant center dedicated to integrating engineering into cancer therapies – but its roots didn’t actually stem from cancer research. Read about how it began with an idea and a seed grant: https://lnkd.in/e2eSVnvi #cancerbioengineering #cancerdrugs #cancertrials #modeling #cellmigration #drugdevelopment #biomedicalengineering #bioengineering

Check out this excellent blog post discussing the most recent issue of Cancer Discovery, which features our prescient commentaries about the future of cancer research. #cancerdiscovery American Association for Cancer Research #AACR2024

What is the role of the TME in lung cancer evolution? - Charles Swanton American Association for Cancer Research The Francis Crick Institute Cancer Research UK (CRUK) https://lnkd.in/dXsdHmrA #Biomarkers #Cancer #CancerResearch #CD8 #LungCancer #Metastasis #MyeloidCells #BiomedicalResearch #NSCLC #OncoDaily #Oncology

A relevant topic in oncology

Each generation of researchers brings with them new ideas on how we can extend lives and (someday) cure pancreatic cancer. Let’s Win, along with the American Association for Cancer Research, supported several scholars-in-training at the 2024 American Association for Cancer Research Special Conference: Advances in Pancreatic Cancer Research in September. Meet the newest generation of researchers and see how they are setting the stage for better outcomes in the future. https://lnkd.in/efdgJjfh #PancreaticCancer #CancerResearch

"A high-tech double-barrel nanopipette, developed by University of Leeds scientists, and applied to the global medical challenge of cancer, has—for the first time—enabled researchers to see how individual living cancer cells react to treatment and change over time—providing vital understanding that could help doctors develop more effective cancer medication. Their findings are published in the journal Science Advances. The tool has two nanoscopic needles, meaning it can simultaneously inject and extract a sample from the same cell, expanding its potential uses. And the platform's high level of semi-automation has sped up the process dramatically, enabling scientists to extract data from many more individual cells, with far greater accuracy and efficiency than previously possible, the study shows." #cancer #oncology

The Scientist spoke with our scientific co-founder, Christopher A. Klebanoff, M.D., about his search for the ‘holy grail’ of cancer targets, such as #KRAS and #p53. Diving into the difficulties of #cancer biology and exploring promising avenues of research, Dr. Klebanoff sheds light on his pursuit of breakthroughs in #oncology. Read more here: https://lnkd.in/gXnrhmTM 

https://lnkd.in/gFM7kVV6 💡 The random forest survival algorithm for predicting the parameters influencing long-terme survival in breast cancer

“What . . . has (been) discovered is a key protein that's secreted from CAFs in breast cancer brain metastases and that increases the invasive capacity of the cancer cells. This secreted protein, if it makes it to circulation, could potentially represent a new liquid biopsy test, which may hopefully be [able to detect brain metastases] faster and earlier than current screening approaches. #mrd #breastcancer #liquidbiopsy #precisionmedicine #cancerresearch #precisiononcology #cancer #genomics #wgs