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Dive into the latest ASHI Insights: "T-FINDER: A pan-HLA platform for T cell receptor discovery" in Science Advances. Explore innovative methods for identifying T cell epitopes and receptors. https://lnkd.in/gSfQbp7T #ASHIInsights #ScienceAdvances #TCellResearch

Liquid biopsies hold a wealth of information, including information from circulating tumor cells (CTCs ) in peripheral blood — which can help with prognosis, treatment monitoring and patient response prediction. To uncover this data, speak to us. We can help you unlock crucial insights — even in large-scale clinical trials — by performing longitudinal analysis of liquid biopsy samples using cutting-edge technologies like RareCyte®. Learn more here ➡️ https://bit.ly/3RciWwl #Biomarkers #ClinicalTrials #PrecisionMedicine

that was an important step for immunology studies in several fields (autoimmunity, vaccinology, rare diseases, DNA editing, etc.)

Let’s take a deeper dive into the biology together.

The quantity of circulating tumor cells in peripheral blood is an important marker for tumor progression. Characterizing CTCs provides important insights into tumor biology. CTC monitoring is especially beneficial when tissue biopsies are not feasible or practical; it can guide therapy for patients with inaccessible or highly heterogeneous tumors.

A very nice review (open access) by T. Morisaki and Tim Stasevich of the latest developments in the field of single-molecule detection of translation in living cells. #mRNA #Translation #smFISH #livecell #imaging https://lnkd.in/eREkq6AF Translation Dynamics of Single mRNAs in Live Cells | Annual Reviews The importance of fundamental research to understand the complexity of translational regulation in order to produce new therapeutics in the coming years!

#Review Detection of Alpha-Fetoprotein Using Aptamer-Based Sensors by Lei Liu and Li Gao https://lnkd.in/gQ5Ncji6   #MDPI #Aptamer #Biochemical #optical #biosensors #sensors #openaccess   #Abstract Alpha-fetoprotein (AFP) is widely-known as the most commonly used protein biomarker for liver cancer diagnosis at the early stage. Therefore, developing the highly sensitive and reliable method of AFP detection is of essential demand for practical applications. Herein, two types of aptamer-based AFP detection methods, i.e., optical and electrochemical biosensors, are reviewed in detail. The optical biosensors include Raman spectroscopy, dual-polarization interferometry, resonance light-scattering, fluorescence, and chemiluminescence. The electrochemical biosensors include cyclic voltammetry, electrochemical impedance spectroscopy, and giant magnetic impedance. Looking into the future, methods for AFP detection that are high sensitivity, long-term stability, low cost, and operation convenience will continue to be developed.

64Cu-177Lu-DOTATATE is a theranostic radiopharmaceutical used in nuclear medicine for the diagnosis and treatment of neuroendocrine tumors (NETs). It combines the diagnostic properties of 64Cu and the therapeutic properties of 177Lu with the targeting molecule DOTATATE, which binds to somatostatin receptors commonly found on NET cells. This approach allows for both imaging and treatment of tumors, offering a personalized medicine option for patients with NETs. We can mass produce (kg level),process scaling up, pilot supply,raw material supply, and intermediate production. Our production technology is mature and more cost-effective. Feel free to inquire at any time. #64Cu-#177Lu-#DOTATATE #theranostic #radiopharmaceutical #targeting #molecule #imaging and #treatment of #tumors #kg #level #cost#effective https://lnkd.in/gv75v82Y

🧪 Thursday Antibody! We’re excited to kick off a new series where, every Thursday, we’ll spotlight a unique antibody from our collection and our partners. Our goal? To help researchers like you discover the high-quality tools you need for cutting-edge research! For our first edition, we’re showcasing our ATF3 Polyclonal Antibody. 🎯 What makes ATF3 special? ATF3 (Activating Transcription Factor 3) is a key regulator involved in cellular stress responses, apoptosis, and immune regulation. Our polyclonal antibody is highly sensitive, providing excellent specificity and reliable performance in a variety of applications including Western Blot and IHC. Why choose our ATF3 antibody? • ✅ Research area: Epigenetics and Nuclear Signaling • ✅ Validated for multiple applications • ✅ Ready to support your research Curious to learn more or ready to order? 👉 https://lnkd.in/es84if5A Stay tuned every Thursday for more antibody highlights to enhance your research. #ThursdayAntibody #ResearchTools #LifeSciences #Antibodies #ATF3 #PolyclonalAntibody

A molecular dynamics study of AZD4573 and Roscovitine as two potent inhibitors of cyclin dependent kinase 9 https://lnkd.in/gPUapwgz