Locsense’s Post

🕷️🔬 Breaking News! Our latest discovery is buzzing with excitement! Scientists have unlocked a new frontier in venom treatment with 45 groundbreaking antibodies that are set to redefine how we tackle the deadly black widow's bite. 🚀🧬 🧪👩🔬 Curious about how these antibodies work against one of nature's most lethal venoms? Each antibody packs a powerful punch, neutralizing the neurotoxins that can cause severe respiratory and heart complications. 💉🖤 👨🔬🧪 This isn't just a medical breakthrough; it's a leap towards safer, more effective antivenom solutions that move away from traditional horse-derived serums. Imagine a future where black widow bites are no longer deadly but merely a minor inconvenience! 🌍💚 🌐🕷️ Curious to dive deeper into the scientific magic behind these antibodies? Click the link in our bio to learn about the fascinating 'phage display' technology that made this possible! https://lnkd.in/gNghYGv5 🌟📚 Don't forget to follow Karmactive for more updates on how we're making the world safer, one discovery at a time! 🌐🌿 #VenomResearch #MedicalInnovation #Antivenom #SpiderBite #Toxicology #ScienceSaves

>> CORESTA Congress 2024: Advancing Next Generation Product Evaluation Last week, we had the pleasure of participating in the “CORESTA Congress 2024”, organized by the “Cooperation Centre for Scientific Research Relative to Tobacco”. The event brought together over 500 delegates from more than 30 countries, including representatives from companies, research institutes, laboratories, associations, and regulatory bodies, all of whom gathered at the Edinburgh International Convention Centre. We were happy to connect and exchange ideas with many esteemed research partners, particularly in the field of in vitro inhalation research. Our collaborative poster with Alexis Technologies , which showcased the application of the AlveoliX AX12 breathing lung-on-chip for whole aerosols, received a great deal of positive attention. Link to poster: https://lnkd.in/eSaSxKsx A special thanks to David Smart from BAT for his insightful presentation on "In vitro assessment of cigarette smoke using an adverse outcome pathway for chronic obstructive pulmonary disease." His discussion featured the VC10 Smoking Robot with the VC48 Exposure System, a highlight of the congress. Additionally, it was exciting to see Vitrocell exposure devices featured in posters from: > Shigeaki Ito ( Japan Tobacco Inc. (JT) ) Link to poster: https://lnkd.in/erqNZCjH > Michael Hollings ( Labcorp ) Link to poster: https://lnkd.in/efKachJv > Adam Seymour ( Labcorp ) Link to poster: https://lnkd.in/ejxawnjE We truly appreciate their valuable contributions to the event. Looking back, it was an intense yet rewarding few days filled with first-class scientific discussions and innovations. We look forward to continuing these important conversations in the future! #invitro #toxicology #TobaccoHarmReduction #RegulatoryScience

Snakebites injure up to 2.7 million and kill 81,000 to 138,000 people annually, with many venoms causing blood toxicity. In this video, we show a timelapse of a human endothelial tubule - MIMETAS' OrganoReady® Blood Vessel HUVEC platform - exposed to spitting cobra venom in the latest experiment of Flavio Bonanini in collaboration with Matyas Bittenbinder. This innovative research sheds light on the devastating effects of snakebites worldwide, offering a robust and human-relevant platform to study endothelial toxicity and potentially develop life-saving antidotes. Learn more about this specific application in this webinar on combining the OrganoPlate® with a multimode plate readers for toxicity research: https://lnkd.in/dCRgFA_Z Explore the OrganoReady® Blood Vessel HUVEC: https://lnkd.in/dZhChTK #SnakeBites #toxicology #ToxResearch

Happening today! 🇩🇰 If you’re at EUROTOX Congress 2024, don’t miss our session on accelerating safety assessments for carcinogenicity and other endpoints using NAMs. #Eurotox2024 #InSilico #Toxicology

☀️ The Alcohol Essentials Series Starts Now!☀️ The first course to launch in the Alcohol Pharmacokinetics section is Alcohol Absorption, presented by the distinguished Dr. Joey Jones, Director of the Northern Louisiana Criminalistics Laboratory. We are fortunate to have some amazing instructors from around the country present this critical content. Participants of this course will learn about different routes of alcohol administration, the role of the gastrointestinal tract, and other physiological considerations. Significant attention is devoted to understanding factors that do and do not affect the extent and rate of alcohol absorption. The course concludes with a review of best practices in considering alcohol absorption. This foundational course enhances understanding of the behavioral and physiological factors associated with alcohol absorption and will improve investigation, interpretation, and testimony in cases regarding alcohol impairment. This course is live now, with many more to follow. Check out our catalog at https://lnkd.in/gRjhT5d4 or see the roadmap for the Alcohol Essentials series at https://lnkd.in/eCWcgMzn #toxicology #alcohol #forensictoxicology #lawenforcementtraining #DRE #stopdui #drugimpairment

💡Why did Marjana Novic join the ONTOX Scientific Advisory Board? And what does she think about ONTOX's progress? 👇Check out the video below! ✨Our Scientific Advisory Board (Stephane Dhalluin, Marjana Novic, Patience Browne, Paul Whaley, Predrag Kukic) 🔎scrutinises whether #ONTOX is heading towards the desired outcome: 🚀to provide a functional and sustainable solution for advancing chemical risk assessment ❌without 🐭animal testing. #NAMs #toxicology #H2020

Emory's Center for Advanced Emergency Care website is live! You can now register for our first annual conference. Frontiers in Advanced Emergency Care that will take place September 12-13th, 2024. Click the link below and scroll to find Frontiers in Advanced Emergency Care to look at the registration options:https://lnkd.in/eNBDjTHy #EmergencyMedicine #Toxicology #AdvancedEmergencyCare

Technological innovations are making impactful changes to nonclinical #drugdevelopment. Jacketed external telemetry systems have provided a non-invasive approach to collecting continuous #respiratory data while minimizing animal models. In this upcoming webinar, our expert will explore these systems and how they can be paired with #toxicology studies to increase the efficiency of your program while maintaining scientific responsibility. Register: https://okt.to/Lgo6is

We’re very excited to attend EUROTOX 2024, in Copenhagen! 🌍 If you're attending, don’t miss our exhibitor hosted session on Monday 9th September, 12:00 – 13:00 which will discuss ‘Leveraging NAMs to optimise and accelerate safety assessments for carcinogenicity and other complex endpoints’. New approach methodologies (#NAMs), also known as non-animal studies, are increasingly gaining acceptance for human chemical safety assessment. As scientific advancements continue, regulatory guidelines are evolving to incorporate weight-of-evidence (WoE) approaches, reducing the reliance on traditional animal assays. In this session, Dr Alex Cayley and Toni Rogers will highlight the value of using a weight-of-evidence approach to optimise and expediate safety assessments. In addition, they'll present a compelling carcinogenicity case study, focusing on early screening and ICH S1B assessments, demonstrating the practical application of a WoE approach. ✅ Additionally, you'll discover how Lhasa’s innovative in silico solution, #Kaptis, enables confident and informed safety decisions by contextualizing NAMs within an Adverse Outcome Pathway (AOP) framework. Learn more about our session and EUROTOX presence here: https://buff.ly/3WrH3IY #EUROTOX2024 #EUROTOX #Toxicology #AOPs #Copenhagen

💡The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) has just launched the #CRACKIT challenge 44 on advancing #avian #toxicity assessments with #NAMs 🧪 Would you like to know more about it? ✔️ Register now for the launch webinar: https://lnkd.in/eiRTe9zZ ✔️ Take a look at the document below 👇 #chemicalscreening #environmental #riskassessment #toxicology #3Rs