Lyoptimus Thermodynamics’ Post

In the initial phase of developing a new product in the laboratory, one of the main targets is to have a robust formulation which can be #freezedried under aggressive conditions without compromising any quality attribute of the product, such as reconstitution time, cake appearance, activity, or residual moisture. Once a robust formulation and an optimized cycle are achieved, it is time to the scale up in industrial #lyophilizers. Any #freezedryer has performance attributes that limit the sublimation rate, refrigeration capacity, condenser surface area, the upper temperature limit of the heat transfer fluid circulating through the shelves, system geometry such as vapor duct length and diameter, or the dynamics of vapor flow from the chamber to the condenser. f you are in the process of optimizing your #freezedrying product or in the scale-up phase, please do not hesitate to contact us to help you with this critical step. --->> contact@lyoptimus.com

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