Mark Hilliard’s Post

Here Jiang et al characteristics the proteolytic preformed of the following proteases :proteinase K, subtilisin, and thermolysin. With emphasis of coast per run and speed of digestion 🎯 Summary: Jiang et al observed that all three enzymes could produce a digest with in 1-5 minutes Futhermore the cost was significantly low tjat traditional proteomics-grade trypsin by an order of 200-100] fold! Jiang et al where able in their hands to get comparable results to trypsin with theese novel proteases. One note of caution is that Jiang et al where not able identify distinct cleavage patterns alone. The use of machine learning could distinguish true protease products from random cleavages. #massspec #massspectrometry #biopharmaceuticals #chemistry #protomics #biotech #science #scienceandtechnology #sciencecommunication #innovation https://lnkd.in/evZYVUb4