MD Anderson Cancer Center’s Post

Dear All I am pleased to share that Research Paper entitled “Inhibition of STAT3 by 2-Methoxyestradiol suppresses M2 polarization and protumoral functions of macrophages in breast cancer” has been published in “BMC Cancer. https://lnkd.in/gkq6UHiM

Findings provide external and independent validation of the methods applied in the novel Plichta staging system for de novo metastatic breast cancer. https://ja.ma/3PjpHLy

🔎 Today let's focus on ovarian cancer with this insightful article from the Mayo Clinic Comprehensive Cancer Center Blog, exploring the latest treatments and groundbreaking research! 👇 https://hubs.li/Q02G0dK80 #ClinicalTrial #MayoClinic #OvarianCancer

As a researcher actively engaged in #microRNA, #exosomal research and its mRNA networks, I get excited to see progressive updates like this. A clear indication of the potential of #exosomalmiRNA in early cancer diagnosis. Check out our recent review paper on Wiley’s Advanced Biology journal as we comprehensively explore the networks of exosomal miRNAs and intricate influence on key signaling pathways for early diagnosis of #breastcancer: https://lnkd.in/enuxmTke Parth Desai

Scientists have developed a blood test that accurately detects early-stage pancreatic cancer, according to a large study. This liquid biopsy uses blood to find cancer, crucial since pancreatic cancer is often found too late for surgery. Early detection significantly increases the five-year survival rate from 3% to 44%. Developed by Ajay Goel, Ph.D., and his team, the test analyzes small RNA bits released by tumors and was validated in nearly 1,000 people from various countries. Combining this test with one detecting the CA19-9 protein identified 97% of early-stage pancreatic cancer cases accurately. This is great news for patients suffering from pancreatic cancer! #cancerresearch #Pancan #liquidbiopsies #AACR #NCI #technology #cancer #oncology #Cancerdiagnosis

Our pan-tumor analysis on the not-so-elusive HRAS mutation in solid tumors - Samuel Kareff, MD, MPH Cancers MDPI American Society of Clinical Oncology (ASCO) ESMO - European Society for Medical Oncology Caris Life Sciences GILBERTO de lima LOPES Junior Sylvester Comprehensive Cancer Center #AACR #ASCO #Cancer #LungAdenocarcinoma #NSCLC #OncoDaily #Oncology #SolidTumors #CancerResearch

Young people with Ewing’s sarcoma, a highly aggressive bone cancer, have few treatment options and a poor prognosis for recurrence. A Phase I/II clinical trial co-led by Joseph Ludwig, M.D., investigates the ability of the novel small molecule TK216 to disrupt the oncogenic fusion protein EWS-FLI1 in previously treated, relapsed/recurrent Ewing's sarcoma. Findings suggest a potential path forward to investigate prospective drug candidates that target the pathognomonic fusion protein in Ewing's sarcoma and other sarcoma subtypes. Learn more about this and other new research from MD Anderson. #CancerResearch #EndCancer

Very excited to share that our article is now published in Lancet Oncology; a phase 1/2 first-in-human clinical trial utilizing immunoPET-CT imaging to visualize DLL3 expression in patients with small-cell lung cancer (SCLC) and Neuroendocrine Prostate Cancer (NEPC). Thank you to all the patients for their participation in the study. I also want to thank my collaborators and mentors for all their support. https://lnkd.in/exN6MKU4

I'm pleased to share our latest research, published in Cellular Oncology. Our team has identified a 6-molecule surface fingerprint in primary prostate cancer tumors, which appears to predict resistance to docetaxel, a commonly used chemotherapy drug. By identifying these molecular markers early, we may better predict which patients are likely to respond to docetaxel and which may need alternative therapies. This could lead to more personalized treatment plans and improved outcomes for prostate cancer patients. Thank you to first author Stanislav Drapela, our dedicated team, and collaborators for their hard work on this project. We look forward to exploring how this finding can be translated into clinical practice to benefit patients. Special thanks to the Institute of Biophysics, #GAČR, Agentura pro zdravotnický výzkum ČR, NÚVR - Národní ústav pro výzkum rakoviny, St. Anne's University Hospital Brno, Masaryk University Brno, Masaryk Memorial Cancer Institute (MMCI), Erasmus MC, UroLab Innsbruck, and Palacký University in Olomouc for making this work possible. Read the full article here: https://lnkd.in/e857R2ek #ProstateCancer #OncologyResearch #PrecisionMedicine #CancerTreatment

Good stuff coming from the University of Pittsburgh showing us the continued progress in our collective fight to provide the best care possible for patients with cancer. Cancer rehabilitation specialists (PTs, OTs, SLPs, etc) play such a pivotal role in providing the best standard of care. That’s our mission at ReVital Cancer Rehabilitation. #together #optimal #patientcare #cancerrehab #research #oncology