Medipass - Ergéa Group’s Post

https://lnkd.in/dkZe98W3 Technically, adult craniospinal irradiation (CSI) cases are different and more complex than pediatric cases due to the length of the craniospinal axis (40–50 cm for children versus 65–75 cm for adults) and the greater body mass index of adults. VMAT tailors the dose for better uniformity over the CSI, reducing the dose to organs at risk (OARs). Due to the rarity of the disease in adult patients, more research needs to be done on dosimetric data and inter-fraction reproducibility for CSI in AMB patients. This retrospective analysis addresses this gap by examining the treatment outcomes related to dosimetric data, inter-fraction reproducibility, and clinical outcomes in six adult medulloblastoma patients treated with VMAT-CSI (TRUEBEAM Varian) and surface-guided radiotherapy (Vision RT Ltd) No significant toxicities greater than G2 were observed during RT, and only two cases reported decreased platelet counts. The dose to the organs at risk was low and acceptable. The mean dose to the heart, lungs, eyes, stomach, and thyroid were 4.4 Gy, 8.5 Gy, 12 Gy, 8.7 Gy, and 11 Gy, respectively. In all translational directions, repositioning data was inferior to 2 mm in more than 90% of cases. Thanks to all Miulli.art Ilaria Bonaparte Fiorella Di Guglielmo Valerio Davì Roberta Carbonara Maria Paola Ciliberti Alessia Surgo Ente Ecclesiastico Ospedale Generale Regionale 'F. MIULLI' Medipass - Ergéa Group Università LUM

🫀 Case Study: The Role of Cardiac CT in Risk Stratification for Anomalous Aortic Origin of a Coronary Artery (AAOCA) 🫀 We recently assessed a 29-year-old female athlete 🏃♀️ who presented with atypical angina and no family history of sudden cardiac death. To better understand her symptoms and assess risk, we performed a tube-modulated retrospective cardiac CT 🖥️, which revealed an anomalous left anterior descending artery (LAD) arising from the right sinus with a subpulmonic septal course. In this case, cardiac CT proved invaluable for comprehensive risk stratification, focusing on four key criteria: 🔍 Anomalous Coronary Ostium Analysis: Cardiac CT provided a detailed look at the ostium, no critical features like slit-like or acute-angle take-off were identified 💓 LV Wall Motion Abnormalities: By assessing left ventricular wall motion, we confirmed no segmental dysfunction. 🛣️ Arterial Course Analysis: The LAD’s subpulmonic septal course was clearly visualized, helping to rule out high-risk interarterial pathways commonly associated with sudden cardiac death (SCD). 📏 Dynamic Diameter Changes: Cardiac CT allowed us to examine the arterial dimensions throughout the cardiac cycle, ruling out any significant dynamic narrowing or compression in systole. Additionally, ischemia screening through stress echocardiography was negative 🟢, and based on these comprehensive CT findings, the patient was safely cleared to continue competitive sports 🏅. 💡 Clinical Insights: Cardiac CT plays a crucial role in risk stratification for AAOCA by allowing for precise anatomical evaluation. This case underscores the importance of a multi-criteria approach to decision-making, especially in young athletes. While natural history data are limited, understanding high-risk features like an intramural course or specific ostial characteristics is essential for tailored management in AAOCA cases.

Navigating Complexity A pictorial representation of anomalous pulmonary venous connection classification in the pediatric population with volume rendering and multiplanar imaging technique Dr. Ramya Selvaraj Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India Dr. Babu Peter Barnard Institute of Radiology, Madras Medical College, Chennai, Tamil Nadu, India DOI: https://lnkd.in/ezgTdreN Keywords: TAPVC, volume rendering images, anomalous pulmonary drainage, Scimitar Syndrome Abstract Anomalous pulmonary venous connections represent a heterogeneous group of congenital heart diseases in which a part or all of the pulmonary veins drains into the right atrium instead of draining into the left atrium. pulmonary veinous anomalies can manifest as partial or total anomalous drainage due to the abnormal embryological development. Multidetector-CT angiography, with its multiplanar reformatting and volume rendering techniques, precisely offers the information about the three-dimensional anatomy and spatial relationships of the cardiovascular structures. Clinical features of anomalous pulmonary venous connections may be silent or have variable features like neonatal cyanosis, volume overload, and pulmonary arterial hypertension due to the left-to-right shunt, which are often associated with other congenital cardiac disease , so that accurate diagnosis is essential for treatment planning

I strongly believe that the anti inflammatory arterial embolization for some MSK pathology it’s am important tool for treatment of pain. We need to control our patients in first place with the pain scale according to the clinical situation and the reduction in pharmacological treatment however th other side of the card it’s the clinical Follow up to demonstrate and understand the effect of the therapy … this patient has recived TAME for a chronic plantar fasciitis with markedly improvement of the pain after the treatment and now is free of pain; we preformed a control ultrasound with Doppler Power and the thickness of the fascia went down from 0.72 to 0.44 (39%) in two weeks and no Doppler signal ; the patients remains free of pain . Alvaro Valtorta, MD Mateus Picada Correa, MD Yuji Okuno M.D., Ph.D Global Embolization Symposium & Technologies (GEST) CVIR Endovascular SOBRICE - Sociedade Brasileira de Radiologia Intervencionista e Cirurgia Endovascular Frederico Cavalheiro

Why AI is vital in gastrointestinal endoscopy? ‘Say HI to AI in GI’: Empowering Endoscopy & Gastro Workflow Automation AI is vital in clinical medicine, especially in #gastrointestinal #endoscopy. #AI-assisted systems aid in colonoscope insertion, detecting bleeding, #inflammation, and identifying early cancer signs. Colorectal #polyp detection, with high sensitivity and accuracy, matches expert human endoscopists. AI enhances procedure efficiency and optimise resource allocation in hospitals. Further research is needed to integrate AI into endoscopy platforms and train gastroenterologists for workflow automation. Dr Bobby Prasad, MBBS, Consultant Gastroenterologist and Endoscopist, Mayo Clinic Healthcare London Professor Pradeep Bhandari, MBBS, Consultant Gastroenterologist, University of Portsmouth Dr Deena Harji, MBBS, PhD, Consultant Colorectal Surgeon, Manchester University NHS Foundation Trust and Associate Professor, University of Leeds will join us at The Future Hospital Show at GIANT Health Event #GIANT2024 📅 9 December 2024 🕒 14:45 - 15:15 Register now: 🎟️ https://bit.ly/3ZEop3D #Digitalhealth #healthcare #healthtech #innovation

🔬 𝐏𝐡𝐨𝐭𝐨𝐜𝐨𝐥𝐩𝐨𝐬𝐜𝐨𝐩𝐞𝐬 𝐌𝐚𝐫𝐤𝐞𝐭: 𝐄𝐧𝐡𝐚𝐧𝐜𝐢𝐧𝐠 𝐖𝐨𝐦𝐞𝐧'𝐬 𝐇𝐞𝐚𝐥𝐭𝐡 𝐃𝐢𝐚𝐠𝐧𝐨𝐬𝐭𝐢𝐜𝐬 The Photocolposcopes Market is growing due to the increasing prevalence of cervical cancer, the rising awareness of women’s health, and the ongoing efforts to improve early detection of cervical abnormalities. Photocolposcopes are advanced diagnostic devices used during colposcopy procedures to examine the cervix, vagina, and vulva for signs of disease. These devices provide high-resolution, detailed imaging of the cervical area, enabling better visualization of lesions or abnormal tissues that may require further examination or biopsy. The growing focus on preventive healthcare, coupled with advancements in imaging technologies, is driving the adoption of photocolposcopes in clinical practices. 𝗖𝗹𝗶𝗰𝗸 𝗵𝗲𝗿𝗲 𝘁𝗼 𝗗𝗼𝘄𝗻𝗹𝗼𝗮𝗱 𝘁𝗵𝗲 𝗳𝗿𝗲𝗲 𝗦𝗮𝗺𝗽𝗹𝗲 𝗥𝗲𝗽𝗼𝗿𝘁: https://lnkd.in/gkxNnGsw 🌍 Key Market Drivers: 1️⃣ Rising Prevalence of Cervical Cancer: The increasing incidence of cervical cancer worldwide is driving the demand for efficient diagnostic tools such as photocolposcopes to detect precancerous lesions early. 2️⃣ Technological Advancements: Modern photocolposcopes feature advanced imaging technologies such as high-definition video, integrated lighting systems, and digital imaging, improving the accuracy and ease of examinations. 3️⃣ Awareness and Prevention Initiatives: Government and healthcare organizations are increasingly promoting preventive care, driving awareness around cervical health and the importance of early screening. 4️⃣ Minimally Invasive Procedures: The preference for minimally invasive diagnostic and treatment procedures in gynecology is fostering the adoption of photocolposcopes in clinical settings. #Company Olympus Corporation ZEISS Group MedGyn Products, Inc. Lutech OPTOPOL Technology Leisegang GmbH #Type Diagnostic Type Diagnosis and Treatment Type #Applications Hospital Clinics Other 𝐂𝐥𝐢𝐜𝐤 𝐇𝐞𝐫𝐞, 𝐓𝐨 𝐁𝐮𝐲 𝐏𝐫𝐞𝐦𝐢𝐮𝐦 𝐑𝐞𝐩𝐨𝐫𝐭 https://lnkd.in/g_fq4JDF #Photocolposcopes #WomensHealth #CervicalCancerScreening #Gynecology #DiagnosticTechnology #HealthcareInnovation #CancerPrevention #MedicalDevices

Effect of early administration of tetracosactide on mortality and host response in critically ill patients requiring rescue surgery: a sensitivity analysis of the STOPSHOCK phase 3 randomized controlled trial Effect of Early Administration of Tetracosactide on Mortality and Host Response in Critically Ill Patients Requiring Rescue Surgery Summary Early administration of tetracosactide (TCS10) in critically ill patients undergoing rescue surgery significantly reduced 30-day mortality and improved hemostatic disorders. The drug targeted melanocortin receptors (MCRs) and showed promising results in a phase 3 randomized controlled trial. Key Findings 30-day mortality was significantly lower in the TCS10 group compared to the control group (0 vs. 8 deaths, P < 0.0001). Baseline levels of certain cytokines and lactate were associated with bleeding episodes, independent of TCS10 treatment. TCS10 treatment was associated with reduced bleeding and blood transfusion episodes, with significant improvements in patient outcomes. Implications The sensitivity analysis highlights the potential of TCS10 in improving emergency casualty care. Further large-scale studies are needed to validate these findings and introduce the technology into real-life clinical practice. Clinical Trial Advancements Clinical trials play a crucial role in developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates clinical protocols and research into a single, accessible knowledge base for clinicians, extending the benefits of clinical trials into everyday medical practice. Healthcare Innovation In today’s healthcare environment, streamlining operations is essential. Our mobile apps support scheduling, monitoring treatments, and telemedicine, enhancing workflows and improving patient outcomes. By utilizing AI, clinics can reduce paper routines and expand services digitally, ultimately improving patient care. Learn more about how we can help at aidevmd.com. https://lnkd.in/gEEA3rMY #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics

https://lnkd.in/gNxTni44 Article title: Treatment-assessment of Zygoma-tripod, -quadripod, -arch and Orbital floor Fractures in the Elderly Patient: Results of a Longitudinal Clinical Study of 20 years (1995-2015) with 1318 Patients in a General Traumatology-department and Evidence-based Treatment Suggestions Author(s): Angelo Troedhan* Journal: International Journal of Oral and Craniofacial Science Journal ISSN: 2455-4634 Abstract: The ever growing population of elderly patients aged 70 years and onwards are prone to facial injuries caused by a general degrading medical and mental state. Main cause for zygoma-tripod, -quadripod, -arch and orbital floor fractures are falls, followed by traffic accidents and only to a small extent violence. Surgical reduction for these types of fractures is recommended but not correlated to the general medical and mental state of this patient-group. Aim of the study was to compare the outcomes of surgical treatment versus non-surgical observation. #Zygoma #Injury #TripodFracture #QuadripodFracture #TranscutaneousReduction #OpenReduction #ElderlyPatient #FacialTrauma #MaxillofacialSurgery #CraniomaxillofacialSurgery #Therapy #OralComplicationsOfCancerTherapy #PreventionAndTreatment #Mucositis #Infection #SalivaryGlandHypofunction #Xerostomia #BisphosphonateAssociatedOsteonecrosis #OralImmunology #InnateImmunity #AdaptiveImmunity #OralDiseaseProcesses #MucosalImmunology #SystemicEffectsOfOralInflammation #Peertechz #PeertechzPublications #OpenAccess #ScientificJournals #PeerReviewedJournals #OpenAccessPublishers #OralMicrobiology #MicrobialGenetics #MicrobialBiochemistry #MicrobialPhysiology #Biofilms #Pathogenesis #OralInfections #EcologyOfOralMicrobes #GenomicsOfOralMicrobes #ProteomicsOfOralMicrobes #Metagenomics #Metatranscriptomics #Metaproteomics #DentalRestorations #Bioengineering #DentalMaterials #Biocompatibility #DentalImplants #Biomaterials #Biomimetics #CellBasedTherapy #GeneBasedTherapy #DrugDelivery #OralTissueRegeneration #OralStructures #PeriodontalTissues #PeriodontalLigament #AlveolarBoneResorption #PeriodontalDisease #Bisphosphonates #PulpBiology #PulpTherapy #PulpRegenerativeResponses #CariesDevelopment #CariesPrevention #SalivaryGlandBiology #SalivaryGlandDevelopment #SalivaryGlandPhysiology #SalivaryGlandBiochemistry #SjogrensSyndrome #SalivaryGlandTumors #DentalCaries #PeriodontalDiseases #OrthodonticDevices #EndodonticDevices #Biosensors #DiagnosticImaging #StructuralImaging #DentalInstrumentation

Differentiating the cause of pain and dysfunction due to cervical spine and shoulder pathology presents a difficult clinical challenge in many patients. Furthermore, the anatomic region reported to be painful may mislead the practitioner. Successfully treating these patients requires a careful and complete history and physical examination with appropriate provocative maneuvers. An evidence-based selection of clinical testing also is essential and should be tailored to the most likely underlying cause. When advanced imaging does not reveal a conclusive source of pathology, electromyography and selective injections have been shown to be useful adjuncts, although the sensitivity, specificity, and risk-reward ratio of each test must be considered.

Best case of 2024 🎯Intramyocardial Dissecting Haematoma (IDH)💔: Rare, Complex, and Challenging management! ✅ What Makes IDH Unique? • Pathophysiology in Action 🩸: Blood dissects between myocardial layers, sparing the epicardium and endocardium. • Why It’s Tricky 🔄: • Mimics critical conditions like pseudoaneurysm (narrow neck) and intracavitary thrombus (homogeneous mass). ✅ Echocardiography: Your Primary Diagnostic Tool Echocardiography is not just the first diagnostic step—it’s the go-to modality for understanding and monitoring IDH over time. ✅ What to Look For on Echo 🔍 • Mass Characteristics: • Heterogeneous texture (fresh blood vs. organized thrombus). • No Doppler flow connection to the LV cavity—an essential clue. • Borders Matter: Surrounded by intact endocardium and epicardium, sparing the myocardial wall. • Dynamic Evolution 🕰️. • Early stage: Hypoechoic (recent bleeding). • Later: Hyperechoic (organized thrombus). ✅ Differentiating IDH • Pseudoaneurysm: Bidirectional Doppler flow with a narrow neck. • Intracavitary Thrombus: Homogeneous mass, lacking dissecting planes. ✅When to Use Advanced Imaging 🎥 • CT Imaging: Confirms hyperdensity (unclotted blood) and wall integrity. • MRI Scans: Unparalleled characterization of haemorrhagic nature and tissue viability. ✅ Management: When Stability Is the Key 1. Conservative Approach: • In stable patients, IDH often resolves spontaneously over weeks with close imaging follow-up. 2. Anticoagulation 💊: • A double-edged sword: necessary for embolism prevention but requires cautious titration to avoid bleeding. 3. Surgical Backup 🛠️: Reserved for cases with hemodynamic instability or impending rupture. 💡 Takeaways: 1. Echocardiography Is Your Guide: Recognize the dynamic features of IDH for accurate diagnosis. 2. Leverage Multimodal Imaging 🖼️: CT and MRI complement echo for diagnostic clarity and follow-up. 3. Tailor Management to Stability 🤝: Balance anticoagulation risks and surgical intervention based on patient-specific factors. Fondazione Policlinico Universitario Agostino Gemelli IRCCS