Medistri’s Post

🚀 GC/MS Residual Analysis GC/MS Analysis (also called Gas Chromatography/ Mass Spectrometry) is an analytical process that utilises the capabilities of Mass Spectrometry and Gas Chromatography in order to determine the chemical compounds within a sample. GC/MS Analysis are recognised for being one of the most highly reliable and effective analysis for the pharmaceutical, Biotechnology & Medical Device industries. GC/MS Analysis are also preferable for chemical compounds with low limits of detection. Our customers use our GC/MS Analysis to analysis sample in any size chemical state particularly when sample quantity is restricted. GC/MS Residual Analysis is crucial primarily for safety reasons. Residual solvents can be harmful or toxic. Even if they are not directly harmful, they can react with other substances in the product to form harmful compounds. Therefore, it’s essential to identify and quantify them to ensure the safety of the product. Additionally, the presence of residual solvents can affect the quality of the product. They can cause changes in color, consistency, stability, and odor. By identifying and quantifying these solvents, manufacturers can maintain the quality of their products. Regulatory bodies such as the FDA and EMA have set limits on the levels of residual solvents that are permissible in pharmaceutical products. GC/MS Residual Analysis helps manufacturers comply with these regulations and avoid penalties. Our laboratory works according to ISO 17025 (current version) and is accredited since 2008 by the Swiss Accreditation Service (SAS). All testing can be performed according to European or US pharmacopeias. 🎯 To learn more about Medistri’s GC/MS Residual Analysis, visit on our website https://buff.ly/3zATkmt or directly contact our team at contact@medistri.swiss. 🌐 Learn more: buff.ly/4cQmflI - The Medistri Team #Medistri #Repost

Today’s active pharmaceutical ingredients (APIs) are increasingly complex in structure and challenging for isolation. Effective API particle engineering is playing a critical role in meeting the demands for drug substance and drug product development. Although crystallization process is desired and commonly used as final isolation step for API production, there are many practical challenges from early process development to process scale-up and implementation in the plant. Some of the challenges are inherently related to the molecular structure and/or API crystal properties, such as high solvation propensity, low chemical stability, high oiling tendency, impurity/API structure similarity, etc.. Some are related to the inherent scale-up issues of batch processing, with drastic changes in mass, heat, and momentum transfers in large batch crystallizers. At AIChE annual conference next week, I'll present in the “495 Continuous Crystallization Processes” session and share case studies when continuous crystallization offers robust processing solutions to challenging APIs that are otherwise hard to isolate and produce at large scale. I look forward to fruitful discussions and further learning. #AIChE #crystallization #continuouscrystallization #particleengineering #API #isolation

📚 Practical Manual Lab Pharmaceutical Inorganic Chemistry 💠 Preparing Pharmaceutical Compounds ▶ This involves the step-by-step processes involved in preparing essential pharmaceutical #compounds like calcium carbonate, magnesium carbonate, zinc sulfate, potash alum, boric acid, and aluminum hydroxide. 💠 Limit Tests ▶ This is designed to identify and control the presence of #impurities in pharmaceutical substances. ▶ It includes the limit tests for chloride, sulfate, and iron, understanding their significance in maintaining product #quality and safety. 💠 Identification Tests for Confirming Compound Authenticity ▶ This involves flame tests, precipitation reactions and others as you confirm the presence of these compounds with precision. 💠 Importance ▶ Inorganic pharmaceutical chemistry plays a vital role in the development and #production of various pharmaceutical compounds. ▶ Limit tests ensure the absence of harmful impurities, upholding the #safety and efficacy of medications. ▶ Identification tests provide accurate confirmation of compound identities, preventing misidentification and potential #risks. 👉 Follow Pharma Broadcast and Henry for more updates #PharmaceuticalChemistry #InorganicCompounds #QualityControl #DrugDiscovery

Pharmaffiliates offers its expertise in custom synthesis R&D, CRAMS, and analytical testing services for outsourcing to pharmaceutical organizations. It also provide supports to chemical and pharmaceutical industries with custom synthesis R&D projects, including: · Impurity profiling including forced degradation studies · Identification, Isolation, Purification, Characterization & Synthesis of unknown impurities peak at given RT / RRT as per shared chromatogram & method by client. · Structure elucidations and confirmations (SER) · Determination of RT, RRT and RF by pharmacopeia method. · Impurity Qualification : Impurity analysis & specified testing 🔗 Discover more at : https://lnkd.in/gd8ZpA3p #unknownpeak #unknownimpurity #unknownpeakidentification #peakidentification #impurityisolation #knownimpurity #impurityprofiling #impurityidentification #forcedegradation #impuritypurification #impuritycharacterization #impuritysynthesis #impurityqualification #impurityanalysis #impuritytesting #relatedsubstances #retentiontime #relativeretentiontime #responsefactor #chromatogram #method #methodofanalysis #residualsolvents #prepHPLC #LC #MS #processimpurity #degradationimpurity #PRIs #DRIs #structureelucidation #elucidation #thermaldegradation #chemicaldegradation #photolyticdegradation #RT #RRT #RRF #RF #SER #characterization #API #pharmaimpurity

Separation using thin layer chromatography technology (TLC) is an important technique, especially in pharmaceutical laboratories. Thin-layer chromatography (TLC) is a technique used for separating and analyzing chemical compounds in small samples. It involves placing the sample on a support plate coated with a thin layer of an adsorbent material (such as silica gel or alumina). The compounds are then moved across this layer by different solvents, and specific compounds can be identified by measuring their movement across the layer using various methods, such as UV light exposure or using visualizing agents. TLC can be used in various applications, including separating organic compounds, determining purity, and monitoring organic chemical reactions. It provides a quick and efficient way to assess the purity of compounds and identify specific compounds in samples. Abdullah Olaywi ✏️ #TLC #qc #thin_layer_chromatography #Labratory #pharmaceutical #qualitycontrol #qualitycontrol

Table Top Shakers: Applications: Mixing and Blending: Ideal for achieving homogeneous mixtures of various chemical or biological samples, ensuring consistent results in laboratory procedures. Cell Culture: Provides precise and gentle shaking required for the growth and maintenance of cell cultures, enabling high-quality experimental outcomes. Chemical Reactions: Ensures controlled agitation for chemical reactions, aiding in faster reaction times and better interaction between reagents. Sample Preparation: Helps in the preparation of biological, chemical, or pharmaceutical samples, offering efficient and accurate pre-processing. Pharmaceutical Testing: Supports reliable testing and formulation procedures for pharmaceutical products, maintaining accuracy and consistency in the lab. Fo r more details visit www.labnlife.com #mixingandblending #cellculture #chemicalreactions #samplepreparation #pharmaceuticaltesting #laboratoryequipment #precisionresearch #labnlife #innovationinlabs

Hello Comunnity, This is me analyzing samples in FTIR. This technique allows the identification of functional groups and can be used to characterize pharmaceutical materials. So, Fourier Transform Infrared Spectroscopy (FTIR) has emerged as a versatile analytical tool in pharmaceutical sciences. By probing the vibrational frequencies of molecular bonds, FTIR enables the identification of functional groups within a sample. This technique is invaluable for characterizing pharmaceutical materials, from raw materials to final products. FTIR's non-destructive nature, rapid analysis time, and ability to provide detailed structural information make it a cornerstone in quality control, formulation development, and impurity profiling. Applications encompass the identification of excipients, polymorph screening, quantification of active pharmaceutical ingredients, and the detection of degradation products. In essence, FTIR offers a comprehensive analytical approach for ensuring the safety and efficacy of pharmaceutical formulations. #caracterization #uepb #ftir #science #deliverysystem

The Power of Charged Aerosol Detection (CAD) in Pharmaceutical Analysis The Thermo Fisher Scientific Charged Aerosol Detector (CAD) is an invaluable tool in the world of pharmaceutical analysis. It provides a universal and highly sensitive method for detecting and quantifying non-volatile and semi-volatile compounds, even those without chromophores. Here’s why the CAD detector is essential for pharmaceutical applications: 🔬 Broad Detection Range: The CAD detector can analyze both small molecules and larger polymers, making it a versatile tool for complex formulations in drug development. 💡 Non-Volatile Compound Detection: Ideal for APIs (Active Pharmaceutical Ingredients) and excipients that are typically hard to detect using UV or mass spectrometry. 📈 Quantitative Accuracy: With a dynamic range that covers both low and high concentrations, CAD offers consistent and reliable results, crucial for formulation stability studies and quality control. 🌱 Applications in Pharma: From drug purity testing to formulation stability and dissolution studies, the CAD detector ensures high sensitivity and precision, supporting critical decisions in drug development and regulatory compliance. The future of pharmaceutical innovation lies in the precision and reliability of our analytical tools, and the CAD detector is playing a significant role in ensuring the safety and efficacy of medications that improve lives. MESLO Egypt and North Africa for Scientific Equipment #mesloegypt #PharmaceuticalAnalysis #ThermoFisherScientific #ChargedAerosolDetection #DrugDevelopment #QualityControl #AnalyticalChemistry