Midea Biomedical’s Post

Dive into quantitation of human insulin-like growth factor-1 and 2 this #TechnicalNoteTuesday This MRM-based LC-MS/MS workflow with scheduled ionization using the SCIEX QTRAP 6500+ enables: 📢Superior quantitation of IGF-1 and IGF-2 with high sensitivity, speed, reproducibility and robustness for biological analytes 📢Robust quantitation over five orders of linear dynamic range for enhanced breadth of applications Read more: https://sciex.li/csuv2r #MassSpectrometry #BiomarkerQuant #ProteomicsQuant

I am delighted to announce the #publication of our lattest #research, "Towards Enhanced Tunability of Aqueous Biphasic Systems: Furthering the Grasp of Fluorinated #IonicLiquids in the Purification of Proteins"! Our findings suggest that FIL-based #AqueousBiphasicSystems provide an improved #ProteinExtraction step, with unparalleled biocompatibility, tunability, and selectivity. In this study, we investigated the remarkable potential of functionalized ABSs made from #FluorinatedIonicLiquids (FILs) as new options for efficient and customizable #ProteinPurification procedures. >> Read the full paper to dive deeper into our methods and results: International Journal of Molecular Sciences MDPI 2024, 25(11), 5766; in https://lnkd.in/d6NzbUjZ Feel free to reach out if you have any questions or would like to discuss our research further! 😊

𝗛𝗼𝘄 𝗱𝗼𝗲𝘀 𝗺𝗮𝘀𝘀 𝗽𝗵𝗼𝘁𝗼𝗺𝗲𝘁𝗿𝘆 𝘄𝗼𝗿𝗸? Mass photometry is a novel bioanalytical technology that measures molecular mass by quantifying light scattering from individual biomolecules in solution. This approach opens up new possibilities for bioanalytics and research into the functions of biomolecules. Some 𝗸𝗲𝘆 𝗵𝗶𝗴𝗵𝗹𝗶𝗴𝗵𝘁𝘀 include: - accurately mass measure a single molecule in solution, in its native state without the need for labels - optimize sample and buffer conditions before moving to more complex technologies - measure the assembly and disassembly of multicomponent complexes If you're interested in learning more about this exciting technology, check out this article that explains how mass photometry works: https://lnkd.in/eJH6AV87. #MassPhotometry #Bioanalytics #Research #Biomolecules

Organoid Intelligence (OI) blends the ability of biological systems with machine intelligence, offering a bold new frontier in biocomputing.  Read more - https://lnkd.in/gywarMTY #OrganoidIntelligence #Biocomputing #ArtificialIntelligence #Innovation #TechTrends #MachineIntelligence #FutureOfComputing #TechInnovation #AIResearch #EmergingTech #OI #TechnologyInsights #VeeTechnologies 

#Article Highly-Cited Paper Detection of Acetoin and Diacetyl by a Tobacco Mosaic Virus-Assisted Field-Effect Biosensor by Melanie Welden, et al. https://lnkd.in/eHAv63E7   MDPI University of Stuttgart FH Aachen University of Applied Sciences The Philipp University of Marburg #diacetyl #acetoin #capacitivefieldeffectbiosensor #tobaccomosaicvirus #acetoinreductase #alcoholicbeverages #openaccess This article belongs to the Special Issue Nanostructured Devices for Biochemical Sensing https://lnkd.in/gFcwMqWA

Numerous techniques have been explored for preparing and sterilizing amniotic membrane for clinical applications. Take a look at this paper to read how researchers from USAISR worked with NovaSterilis to advance a novel technique using #scCO2 to achieve SAL 10-6 sterility while preserving #tissue matrix performance. Read more here: https://bit.ly/3RPYNfH

Excited to share my latest research on the dynamic behavior of the tautomerase superfamily (TSF)! Just published in the International Journal of Molecular Sciences: "Conformational Flexibility of the C-Terminal Region Influences Distal Active Site Residues Across the Tautomerase Superfamily". In this study, we used molecular dynamics simulations to investigate how the C-terminal region of these proteins influences their function. We found that the C-terminal region of bacterial TSF proteins is highly flexible and that this flexibility may be key to their diverse roles. We also found that the C-terminal communicates with distant parts of the protein, including the active site, suggesting a role in regulating enzymatic activity. Check out the full article here: https://lnkd.in/gEwB6aZM #ProteinDynamics #MD #MDPI #IJMS

Monitoring protein-protein interactions at a molecular level using SSN https://lnkd.in/gBXC4yp3

Research paper in Collagen and Leather: The #chondrogenic differentiation of BMSCs in #collagen hydrogels and the effect of MMPs among cell-material interactions Yajun Tang, Jing Wang, He Qiu, Yang Xu, Zhanhong Liu, Lu Song, Hai Lin* and Xingdong Zhang from 四川大学 https://lnkd.in/gctdi_zG

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments. Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful biophysical technique being increasingly applied to a wide variety of problems. As the HDX-MS community continues to grow, adoption of best practices in data collection, analysis, presentation and interpretation will greatly enhance the accessibility of this technique to nonspecialists. https://hubs.ly/Q02sp2ZV0