MoniCardi’s Post

🚨 Breakthrough in Heart Failure Treatment: Heart Muscle Regeneration 💖 Researchers at the University of Arizona have made an exciting discovery—artificial hearts can potentially trigger heart muscle regeneration. Published in Circulation, the study shows that these devices allow the heart to "rest," similar to healing after a muscle injury, enabling regeneration in some patients. 🔬 Key Findings: Patients with artificial hearts regenerate muscle cells at 6x the rate of healthy hearts. This reinforces the potential for the heart to regenerate, challenging long-held beliefs. Could lead to revolutionary treatments for 7M+ Americans affected by heart failure.

#heartdisease #cardiology #health https://lnkd.in/gHft8gQc Abstract Psychological #stress is generally accepted to be associated with an increased risk of #cardiovascular #disease (CVD), but results have varied in terms of how stress is measured and the strength of the association. Additionally, the mechanisms and potential causal links have remained speculative despite decades of research. The physiological responses to stress are well characterized, but their contribution to the development and progression of CVD has received little attention in empirical studies. Evidence suggests that physiological responses to stress have a fundamental role in the risk of CVD and that haemodynamic, vascular and immune perturbations triggered by stress are especially implicated. Stress response physiology is regulated by the corticolimbic regions of the brain, which have outputs to the autonomic nervous system. Variation in these regulatory pathways might explain interindividual differences in vulnerability to stress. Dynamic perturbations in autonomic, immune and vascular functions are probably also implicated as CVD risk mechanisms of chronic, recurring and cumulative stressful exposures, but more data are needed from prospective studies and from assessments in real-life situations. Psychological assessment remains insufficiently recognized in clinical care and prevention. Although stress-reduction interventions might mitigate perceived stress levels and potentially reduce cardiovascular risk, more data from randomized trials are needed.

I found this article from Mayo Clinic very insightful. The research findings indicating a correlation between prolonged bed rest and cardiovascular and neuromuscular deconditioning are quite significant. Dr. Scarisbrick's summary explains how elevated levels of serum markers linked to neural injury and inflammation are associated with declines in neural reflex control. This, in turn, contributes to cardiovascular and postural deconditioning, especially in older adults. Understanding these mechanisms helps us better comprehend the effects of bed rest on both cardiovascular health and neurodegeneration, particularly in older adults. This new perspective opens up opportunities for developing improved exercise and biotherapeutic interventions. As physiotherapists, it underscores the importance of tailored rehabilitation programs aimed at cardiovascular function, maintaining neural reflex control, and preventing the adverse effects of bed rest on overall health and well-being. Did any healthcare professionals, encountered the effects of prolonged bed rest in your patients? Read the full article here: https://lnkd.in/gEriXMvB #Physiotherapy #CardiovascularHealth #NeuromuscularDeconditioning #BedRestEffects #MayoClinic #HealthResearch #insights

#Doctors (and #CMS #Medicare) often overlook the familiar "General Deconditioning" diagnosis (ICD-10 R53.81) as prosaic and diagnostically pedestrian. However, we have compelling data that "deconditioning" is likely a symptom that reflects a larger scale physiological process happening on a multi-system level. Check out this illuminating article articulating the science behind getting weak, and how #exercise can help these symptoms. Can we as #physiatrists help change to perception of #deconditioning? #NationalRehabAwarenessWeek https://lnkd.in/gbuASsvp "In this pilot study, we examined levels of several inflammatory and neurodegenerative markers to assess their relationship with neural deficits in cardiac and muscle-pump baroreflexes, and with physical and physiological declines commonly associated with bed rest," explains Dr. Scarisbrick. "We also explored whether 60 to 75 minutes of daily exercise can reduce bed rest-induced cardiovascular and skeletal muscle deconditioning."

🧠 In a pioneering effort to tackle post-stroke fatigue (PSF), a prevalent yet often overlooked condition among #stroke survivors, a new study used our #Starstim device for HD-tDCS sessions, aiming to illuminate the path toward effective #neuromodulation treatments. Could this be the breakthrough we've been waiting for in PSF management? 🤔 🔬 This randomized-controlled crossover trial focused on the use of HD-tDCS to stimulate specific brain regions associated with PSF. Twenty participants received stimulation across the dorsolateral prefrontal, motor, and parietal cortex, complemented by resting-state #EEG analysis before and after each session. The study's goal was to pinpoint the optimal cortical stimulation sites for reducing PSF, marking a significant step forward in our approach to neuromodulation therapies. 👉 Uncover the full details and implications of this innovative research here: https://lnkd.in/gba29X43 🎉 Heartfelt congratulations to the researchers: Akhila Jagadish, Manikandan Natarajan, Divya Adhia, Annapoorna Kuppuswamy, vasudeva guddattu, Dr. John Solomon.  Your work paves the way for new horizons in patient care. 🌟 #Research #Medtech #Electroceuticals #Technology #Healthtech #Healthcare #Science #Innovation #Study #ResearchArticle #Neuroscience #Neurotechnology #tDCS #BrainStimulation #tACS #tES Elsevier Manipal Academy of Higher Education, Prasanna School of Public Health, University of Otago, University of Leeds.

Description: Cardiac sarcoidosis is a rare inflammatory disease that affects the heart. It can lead to arrhythmias, heart failure, and sudden cardiac death. Imaging Technique: A combined PET-CT scan has shown success in detecting cardiac sarcoidosis. Researchers at the University of Illinois at Chicago (UIC) developed a new technique that incorporates a 72-hour high-fat, low-sugar diet before images are taken. This approach improves accuracy in diagnosing cardiac sarcoidosis, which is often unpredictable and difficult to detect using standard protocols. Treatment: Treatment involves immunosuppressive medications, antiarrhythmics, and close monitoring. Harvard Medical School Harvard Public Health magazine Stanford University School of Medicine Apollo Hospitals Indian Radiological & Imaging Association #Radiology #DiagnosticRadiology #InterventionalRadiology #NuclearMedicine #PETCT #CTscan #HealthcareInnovation

September scientific article now available to download: Title: Education and training of the radiography workforce when caring for people living with dementia Author(s): Dr Rob Higgins, Dr Adam Spacey, Professor Anthea Innes Hospital: University of Salford; McMaster University, Canada As the population ages, the prevalence of dementia continues to rise. Dementia is an umbrella term for several diseases affecting memory, cognitive abilities, mood and behaviour changes that interfere significantly with a person’s ability to maintain their activities of daily living. Although age is the strongest known risk factor for dementia, it is not a normal part of ageing and worldwide approximately 55 million people are living with dementia (PLWD), and its prevalence is increasing internationally. Radiography plays a vital role in diagnosing and monitoring the progression of dementia. Neuroimaging techniques such as CT and MRI can be used to detect structural changes in the brain that may indicate dementia. Nuclear medicine brain perfusion imaging, using dopamine active transporter (DAT) or fluorodeoxyglucose-PET (FDG-PET) scans can reveal patterns of brain activity that may suggest dementia. https://lnkd.in/eRfXNZwr #RADMagazine #medicalimaging #healthcare #medical #radiology #dementia #PET

A new study from Greta K. Wood, Brendan F. Sargent, Zain-Ul-Abideen Ahmad, et al. reveals that "12-18 months after hospitalization for #COVID19, patients show significant cognitive decline comparable to 20 years of aging. MRI scans and blood tests also show brain injury markers and reduced brain volume in these patients. The findings suggest that COVID-19 has lasting effects on brain health, even in those without neurological complications." "It is important to emphasize that these were patients who had experienced #COVID requiring hospitalization and these results shouldn’t be too widely generalized to all people with lived experience of COVID." Learn More in Nature Medicine | Nature Portfolio https://lnkd.in/gf8MvNFv Post-hospitalisation COVID-19 cognitive deficits at one year are global and associated with elevated brain injury markers and grey matter volume reduction - Greta Wood, Brendan Sargent, Zain-Ul-Abideen Ahmad, COVID-CNS Consortium, Benedict D. Michael, Stella-Maria Paddick, E. Charles Leek, et al. University of Liverpool King's College London University of Cambridge COVID-CNS Consortium Neuroscience News https://lnkd.in/gsMV3Qc8

Prediction of left ventricle ejection fraction from HRV in diabetics and cardiac diseased subjects: A mathematical model approach https://lnkd.in/gTN7qnCi Heart Rate variability (HRV) is the variation between beat-to-beat intervals in a consecutive heartbeat. HRV provides enormous information about cardiac health. Electrocardiogram and echocardiography (2D echo) are the two major techniques used by medical practitioners to diagnose cardiac health. The 2D echo provides more accurate results as compared to electrocardiography but costs ten times more. This research provides low-cost solution for cardiac health diagnosis to the level of 2D echo derived from the electrocardiogram. ECG and the 2D echo data of the same cohort are collected from 15 diabetics and 15 cardiac-diseased subjects. In this research, we found a correlation between significant HRV parameters and 2D Echo parameters. Maximum correlation is obtained between LF/HF (low-frequency power to high-frequency power ratio), the HRV parameter, and LVEF (left ventricle ejection fraction), the 2D echo parameter. We derived various mathematical models, to predict the LVEF, from LF/HF for both cardiac diseased and diabetics separately. The combined best-fit model is obtained using nonlinear regression with the goodness of fit, R2 = 94.54 %. #Left ventricle ejection fraction #Heart rate variability #Autonomous nervous system #Cardiac health #Diabetes #technology #research #innovation

Electroencephalography (EEG) is a technique for recording and interpreting the electrical activity of the brain. The electroencephalogram (EEG) represents the recording, over time, of the brain's electrical activity. The recording is done by means of electrodes placed on the scalp, connected to a device called electroencephalograph. Brain activity is based on connections and communication between neurons, which is achieved by transmitting small electrical signals, called electrical impulses. They create electrical potentials that are received by electrodes placed on the scalp, and the paths recorded on the electroencephalogram represent the variation of the potential differences between the pairs of electrodes selected by the examiner. Represented graphically, the cerebral electrical activity is recorded through certain sequences of sinusoidal or sharp waves, synchronous or asynchronous, rhythmic or seemingly random, which allow the characterization of the route as physiological (normal) or with lesional or irritating changes (pathological). The electroencephalogram (EEG) is an important examination in the diagnosis of epilepsy. And it can be indicated in the diagnosis of confusional syndrome, fainting states, cranio-cerebral trauma, tumors, brain infections, providing information about the existence and location of a brain injury or trigger for epileptic seizures. Also, polysomnography is used to diagnose sleep disorders. In the case of performing an electroencephalogram, the risks are minimal, but intermittent light stimulation or hyperventilation can produce epileptic seizures and therefore the examination is performed under the supervision of a doctor who can recognize the seizure and immediately institute the appropriate safety and therapeutic measures. Remember: the electroencephalogram (EEG) is not a test to quantify intelligence! A normal result of an electroencephalogram (EEG) in a person who has had an epileptic seizure does not deny the probability of the diagnosis of epilepsy. #CONTEC #KT88 #digitalbrainelectricactivitymapping #EEG #medicaldevice #Electroencephalography #hospital #clinics #epilepsy #faintingstates #craniocerebraltrauma #tumors #braininfections