https://lnkd.in/gWu7Zzwg Article title: Perrotta Integrative Clinical Interviews (PICI-2): Innovations to the first model, the study on the new modality of personological investigation, trait diagnosis and state diagnosis, and the analysis of functional and dysfunctional personality traits. An integrated study of the dynamic, behavioural, cognitive and constructivist models in psychopathological diagnosis. Research Author(s): Giulio Perrotta Journal: Annals of Psychiatry and Treatment Journal ISSN: 2640-8031 Abstract: Purpose: As a result of clinical findings it is necessary to make some changes to the previous model, the first version. The second version of the PICI model (Perrotta Integrative Clinical Interviews) improves the previous version by introducing some interpretative corrections, especially with regard to dysfunctional hyperactivation, unitary diagnosis, symptomatological persistence, categorical absorption, trait diagnosis and state diagnosis, egosyntony and egodystonia, reducing the items from 150 to 128 for the PICI-2C questionnaire and from 195 to 173 for the PICI-2TA questionnaire. The second version of the PICI is also enriched by a third questionnaire, PICI-2FT, always administered by the therapist after the clinical interview, with 18 items, capable of investigating functional personality traits and thus completing in a more descriptive way the personality picture of the patient in its functional and structural totality. #PersonalityDisorders #PICI1 #PICI2 #MMPIIII #BiologicalPsychiatry #Psychopharmacotherapy #PsychologicalMedicine #ForensicPsychiatry #SocialPsychiatry #Sociotherapy #PTSD #Peertechz #PeertechzPublications #ChildAndAdolescentPsychiatry #AddictionPsychiatry #MoodDisorders #Nosography #Schizophrenia
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https://lnkd.in/g-NFY8Gw Article title: Cariprazine in therapy of visual hallucinations. Randomized, double-blind placebo-controlled study Author(s): NA Aliyev; ZN Aliyev Journal: Annals of Psychiatry and Treatment Journal ISSN: 2640-8031 Abstract: Objective: We studied cariprazine in therapy of visual hallucinations with a therapeutic resistance due to traumatic brain injury randomized, double-blind placebo-controlled study manner. Methods: To traumatic brain injury hundred patients (100 all men) whom we studied were under observation in Mental Health Center of the Ministry of Health of the Republic of Azerbaijan from January 2020 to June 2021. The method of randomization was given by lottery []. Each patient was randomized to receive either in agreement of the instruction cariprazine (50 patients) over 5 day in dose 6 mg one times per os in morning after meet for 12 weeks or matched placebo (50 patients) in a double-blind manner. A structured clinical interview, for DSM-5Axis I Disorder, Patient Edition, was used to diagnose according to DSM-5 major or mild neurocognitive disorder due to traumatic brain injury. #Cariprazine #VisualHallucinations #TherapeuticResistance #TraumaticBrainInjury #BiologicalPsychiatry #Psychopharmacotherapy #PsychologicalMedicine #ForensicPsychiatry #SocialPsychiatry #Sociotherapy #PTSD #Peertechz #PeertechzPublications #ChildAndAdolescentPsychiatry #AddictionPsychiatry #MoodDisorders #Nosography #Schizophrenia
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https://lnkd.in/gMwdTqnk Article title: Clinical evidence in the phenomenon of Alien Abduction Author(s): Giulio Perrotta Journal: Annals of Psychiatry and Treatment Journal ISSN: 2640-8031 Abstract: Purpose: Starting from the classic definition of “alien abduction”, the present research, starting from the study published in 2020 on the proposed clinical classification of this particular phenomenon, is aimed at confirming the theoretical assumption of psychopathological origin. Methods: Clinical interview, based on narrative-anamnestic and documentary evidence and the basis of the Perrotta Human Emotions Model (PHEM) concerning their emotional and perceptual-reactive experience, and administration of the battery of psychometric tests published in international scientific journals by the author of this work: 1) Perrotta Integrative Clinical Interviews (PICI-2), to investigate functional and dysfunctional personality traits; 2) Perrotta Individual Sexual Matrix Questionnaire (PSM-Q), to investigate the individual sexual matrix; 3) Perrotta Affective Dependence Questionnaire (PAD-Q), to investigate the profiles of affective and relational dependence; 4) Perrotta Human Defense Mechanisms Questionnaire (PDM-Q), to investigate the defence mechanisms of the Ego. #Alien #AlienAbduction #UFO #PICI2 #PDMQ #PSMQ #PADQ #PHEM #BiologicalPsychiatry #Psychopharmacotherapy #PsychologicalMedicine #ForensicPsychiatry #SocialPsychiatry #Sociotherapy #PTSD #Peertechz #PeertechzPublications #ChildAndAdolescentPsychiatry #AddictionPsychiatry #MoodDisorders #Nosography #Schizophrenia
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As an editor of the special issue of Frontiers in Psychiatry (impact factor 4.7) on Case Reports in Psychopharmacology (Volume II), I invite all interested participants, including clinicians, to submit their clinical cases or case series to our special issue✅: https://lnkd.in/evYPbd45 You have a nice opportunity to discuss clinical psychopharmacology in clinical practice ✅ . #Psychiatry #Psychopharmacology #Frontiers
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In collaboration with STALICLA, clinical Phase 1 trials are being led by Drs. Suchitra Krishnan-sarin, John Krystal and Stephanie O'Malley from the Department of Psychiatry of the Yale University School of Medicine under a center grant from the National Institute on Alcohol Abuse and Alcoholism. One of the studies aims to conduct a comprehensive examination of the influence of STP7 (Mavoglurant) on alcohol drinking behaviors among heavy drinkers. The study will also assess the potential of mavoglurant as a treatment candidate to benefit patients affected by Alcohol Use Disorder. Under the agreement, STALICLA will provide STP7 (Mavoglurant) to the principal investigator of the NIAAA center, Dr. John Krystal. Dr. Krystal is a leading expert in the areas of substance use disorders, post-traumatic stress disorder, schizophrenia, and depression, and is currently Chair of the Department of Psychiatry of the Yale University School of Medicine. #Stalicla #Neurology #Innovation #Biotechnology #CNS #precisionmedicine #neuropsychiatry
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Long noncoding RNAs emerge as promising biomarkers for mood disorders. New review highlights potential of blood-based RNA molecules for diagnosis and treatment of depression and bipolar disorder. In a groundbreaking peer-reviewed review article, researchers have uncovered compelling evidence that long noncoding RNAs - molecules once dismissed as "junk DNA" - may hold the key to revolutionizing how we diagnose and treat mood disorders. The study, published in the journal Genomic Psychiatry (Genomic Press, New York), reveals that these RNA molecules circulating in blood samples could serve as powerful biomarkers for conditions like major depression and bipolar disorder, potentially leading to more accurate diagnoses and personalized treatments. For more information, click here for the full, open-access PDF: https://lnkd.in/dCnX5gaT The EurekAlert! news release can be found here: https://lnkd.in/dGV_5efy #UAB #YogeshDwivedi #MentalHealth #MentalHealthMatters #LncRNABiomarkers #MoodDisorderResearch #DepressionBiology #BipolarBiomarkers #PsychiatricGenomics #EpigeneticsAndMentalHealth #CirculatingLncRNA #PersonalizedPsychiatry #BrainEpigenetics #MolecularPsychiatry #PrecisionMentalHealth #BiomarkerDiscovery #DepressionDiagnosis #BipolarTreatment #NoncodingRNA #PsychiatricBiomarkers #MentalHealthGenomics #RNABiomarkers #BloodBasedBiomarkers #FutureOfPsychiatry
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https://lnkd.in/gbqk_yKX Article title: A Child of Wilson’s Disease Presenting with Coprolalia Author(s): Bhavuk Garg; Sumit Kumar Gupta* Journal: Annals of Psychiatry and Treatment Journal ISSN: 2640-8031 Abstract: Wilson’s disease is a rare autosomal recessive genetic disorder of copper metabolism. Neurological and psychiatric manifestations can be a presenting manifestation of Wilson’s disease. We describe a case of a 13 year old child diagnosed with Wilson’s disease who presented with coprolalia (complex vocal tics). Tics can be present in Wilson’s disease, but they are usually described to be simple motor tics. Vocal tics especially complex vocal tics and that too specifically coprolalia has not been described previously in the literature to the best of our knowledge. #WilsonsDisease #Tics #Coprolalia #TourettesSyndrome #BiologicalPsychiatry #Psychopharmacotherapy #PsychologicalMedicine #ForensicPsychiatry #SocialPsychiatry #Sociotherapy #PTSD #Peertechz #PeertechzPublications #ChildAndAdolescentPsychiatry #AddictionPsychiatry #MoodDisorders #Nosography #Schizophrenia
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🎉 Exciting News! A study led by Dr. SAMIRA VALVASSORI's group, in which I had the pleasure of collaborating, has just been published in the European Archives of Psychiatry and Clinical Neuroscience! This study explores the long-term impact of early life stress on mental health, shedding light on how childhood maltreatment can contribute to epigenetic and neurotrophic alterations in individuals with Bipolar Disorder. Understanding these mechanisms is crucial for identifying early biomarkers and improving treatment strategies for mental health disorders. Check out the full text in the link below: https://lnkd.in/gUdC8bYM #MentalHealthResearch #BipolarDisorder #ChildhoodMaltreatment #Epigenetics #Neuroscience #Psychiatry #EarlyIntervention #ClinicalResearch #MentalHealthAwareness #Neuroplasticity #PsychiatricDisorders
Exploring the impact of childhood maltreatment on epigenetic and brain-derived neurotrophic factor changes in bipolar disorder and healthy control - European Archives of Psychiatry and Clinical Neuroscience
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Dr. Jeffrey Finman, CRC's Chief of Biostatistics, played a pivotal role in a recent study featured in the Journal of Clinical Psychiatry, underscoring his expertise in #schizophrenia research. His expert knowledge of #biostatistics was instrumental in analyzing the data, particularly in assessing the efficacy of the treatment for acute agitation in schizophrenia or #schizoaffective disorder patients, as measured by the Positive and Negative Syndrome Scale-Excited Component (PEC) total score. Interested in learning more about CRC's involvement in schizophrenia research and how our biostatistical analysis drives clinical insights? Email info@cogres.com to connect with our experts. #ItsTheTeamThatMatters #WeChangeLives Meet More CRC Schizophrenia Experts: Tom Zoda, Ph.D., Tom Hochadel, Pharm.D., Gary Kay, Ph.D., Dana Soetaert, Brandy Isaacks
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