Swiss Nuclear Doctors’ Post

🔬✨ CT-Less Organ Segmentation in PET: A Deep Learning Preprint ✨🔬 We’re excited to share a preprint led by Yazdan Salimi from Geneva University Hospital, under supervision from Prof. Habib Zaidi, and Dr. Ismini Mainta, proposing a groundbreaking approach to multi-organ segmentation in PET imaging without the need for CT. 🧠📊 🔹 Study Overview: Traditional segmentation in PET imaging relies heavily on CT, but CT-PET alignment issues and PET-only workflows can limit its effectiveness. This study introduces a CT-independent deep learning model using PET emission data alone, addressing these challenges head-on. Models and Data: Advanced nnU-Net models were trained and tested on a dataset of over 2,000 PET/CT images, focusing on 18F-FDG and 68Ga-PSMA tracers. Innovation: By eliminating CT reliance, this pipeline enables consistent, accurate organ segmentation, even in PET-only environments. 🚀 🔹 Key Findings: High Accuracy: Achieved Dice coefficients of 0.81–0.82 for 18F-FDG and 0.77–0.79 for 68Ga-PSMA, with strong performance in organs like the brain and lungs. Versatility: Supports applications in dosimetry, kinetic modeling, and radiomics, expanding the utility of PET imaging in clinical and research settings. GitHub Access: The authors have made their repository publicly available for exploration and feedback — try it out here: 🔗 https://lnkd.in/ejhkigVx 👏 We wish this preprint success in finding a peer-reviewed journal for publication and invite the community to explore and engage with this exciting new approach! 🔗 Read the preprint: https://lnkd.in/eC9HkqNg #NuclearMedicine #DeepLearning #PETImaging #MedicalImaging #ArtificialIntelligence #OrganSegmentation #SwissResearch #OpenScience

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Habibollah Dadgar

Supervisor of RAZAVI Nuclear Medicine department_ Physicist/Researcher

2w

Congratulations Yazdan for your great effort and results from your valuable lab. 👍

Congratulations Yazdan Salimi and Habib Zaidi, FIEEE, FAIMBE, FAAPM, FIOMP, FAAIA, FBIR Such interesting findings. A medical physicist has some challenges in pet and ct simulation fusion on treatment planning system for radiation therapy patients.The combination of this article with TPS or countoring in TPS would be helpful.

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