October is #BreastCancerAwareness month, a time to spotlight the scientific advancements driving the fight against one of the most prevalent cancers worldwide and working to save mothers, daughters, sisters, and friends. Current research is uncovering new insights into personalized therapies, improving diagnostic tools, and exploring the genetic and molecular factors behind tumor progression. These findings are crucial for developing more effective treatments and improving patient outcomes. Explore some of the most impactful studies driving progress in breast cancer detection and treatment, featured in the Breast Cancer community on OiPub: 𝟭. 𝗖𝘂𝘀𝘁𝗼𝗺𝗶𝘇𝗶𝗻𝗴 𝗹𝗼𝗰𝗮𝗹 𝗮𝗻𝗱 𝘀𝘆𝘀𝘁𝗲𝗺𝗶𝗰 𝘁𝗵𝗲𝗿𝗮𝗽𝗶𝗲𝘀 𝗳𝗼𝗿 𝘄𝗼𝗺𝗲𝗻 𝘄𝗶𝘁𝗵 𝗲𝗮𝗿𝗹𝘆 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿: 𝘁𝗵𝗲 𝗦𝘁. 𝗚𝗮𝗹𝗹𝗲𝗻 𝗜𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗖𝗼𝗻𝘀𝗲𝗻𝘀𝘂𝘀 𝗚𝘂𝗶𝗱𝗲𝗹𝗶𝗻𝗲𝘀 𝗳𝗼𝗿 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 𝗼𝗳 𝗲𝗮𝗿𝗹𝘆 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿 𝟮𝟬𝟮𝟭 by H.J. Burstein, G. Curigliano, B. Thürlimann et al. (2021) [𝘖𝘱𝘦𝘯 𝘈𝘳𝘤𝘩𝘪𝘷𝘦] https://lnkd.in/dErdJsQt 𝟮. 𝟱𝘁𝗵 𝗘𝗦𝗢-𝗘𝗦𝗠𝗢 𝗶𝗻𝘁𝗲𝗿𝗻𝗮𝘁𝗶𝗼𝗻𝗮𝗹 𝗰𝗼𝗻𝘀𝗲𝗻𝘀𝘂𝘀 𝗴𝘂𝗶𝗱𝗲𝗹𝗶𝗻𝗲𝘀 𝗳𝗼𝗿 𝗮𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿 (𝗔𝗕𝗖 𝟱) F.Cardoso, S.Paluch-Shimon, E.Senkus et al. (2020) [𝘖𝘱𝘦𝘯 𝘈𝘳𝘤𝘩𝘪𝘷𝘦] https://lnkd.in/dWgqyQbf 𝟯. 𝗔𝗱𝗷𝘂𝘃𝗮𝗻𝘁 𝗮𝗯𝗲𝗺𝗮𝗰𝗶𝗰𝗹𝗶𝗯 𝗰𝗼𝗺𝗯𝗶𝗻𝗲𝗱 𝘄𝗶𝘁𝗵 𝗲𝗻𝗱𝗼𝗰𝗿𝗶𝗻𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆 𝗳𝗼𝗿 𝗵𝗶𝗴𝗵-𝗿𝗶𝘀𝗸 𝗲𝗮𝗿𝗹𝘆 𝗯𝗿𝗲𝗮𝘀𝘁 𝗰𝗮𝗻𝗰𝗲𝗿: 𝘂𝗽𝗱𝗮𝘁𝗲𝗱 𝗲𝗳𝗳𝗶𝗰𝗮𝗰𝘆 𝗮𝗻𝗱 𝗞𝗶-𝟲𝟳 𝗮𝗻𝗮𝗹𝘆𝘀𝗶𝘀 𝗳𝗿𝗼𝗺 𝘁𝗵𝗲 𝗺𝗼𝗻𝗮𝗿𝗰𝗵𝗘 𝘀𝘁𝘂𝗱𝘆 N.Harbeck, P.Rastogi, M.Martin et al. (2021) [𝘖𝘱𝘦𝘯 𝘈𝘤𝘤𝘦𝘴𝘴] https://lnkd.in/dwc3Z6pc You can find more research on the Breast Cancer community at OiPub: https://lnkd.in/d7RJypqz ...or build tailored research communities like the "Dielectric Properties in Breast Cancer Research" community to keep updated on your specific area of interest: https://lnkd.in/dHxJm3m3 #BreastCancerResearch #PinkOctober #MedicalScience #Oncology #CancerResearch #BreastCancer
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"In celebration of #Cancer #Immunotherapy Month, Roger Waltzman, CMO at Indaptus Therapeutics (NASDAQ INDP), sat down for a moment to reflect on his journey. From a young age, the loss of a few family pets sparked his curiosity about diseases, steering him towards a career in medicine. Today, he leads Indaptus' efforts to #revolutionize #cancertreatment by harnessing the power of the #immunesystem to target and destroy cancer cells, and bring #innovative solutions to cancer patients." https://lnkd.in/gPQPzDrR #Pfizer
What sparked your interest in science?
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#Immunity "Know Thyself" | Máté Manczinger & Co. delve into the Concept & Nature of Immunological 'Self' at Proceedings National Academy of Sciences | Implications for #Cancer #Immunotherapy, #VaccineDesign, & Much More | "The identification of immunogenic peptides has become essential in an increasing number of fields in immunology, ranging from tumor immunotherapy to vaccine development. The nature of the adaptive immune response is shaped by the similarity between foreign and self-protein sequences, a concept extensively applied in numerous studies. Can we precisely define the degree of similarity to self? Furthermore, do we accurately define immune self? In the current work, we aim to unravel the conceptual and mechanistic vagueness hindering the assessment of self-similarity. Accordingly, we demonstrate the remarkably low consistency among commonly employed measures and highlight potential avenues for future research". Celentyx Ltd Professor Nicholas Barnes PhD, FBPhS Omar Qureshi Catherine Brady
A journey to your self: The vague definition of immune self and its practical implications | Proceedings of the National Academy of Sciences
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Exciting new study regarding IGSRT!
Freedom from Recurrence across Age in Non-Melanoma Skin Cancer Treated with Image-Guided Superficial Radiation Therapy
mdpi.com
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https://lnkd.in/dPZez-qB via @researchgate https://lnkd.in/dPZez-qB Happy to share that my scientific outcome is reaching different research groups and getting more known. My first published abstract at ESMO - European Society for Medical Oncology- Paris 2024 highlighted the impact of H2S and its synthesizing enzymes on metabolic reprogramming in breast cancer
Kareem Elsayed | Achievement
researchgate.net
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Check out the latest issue of #CellSignals. Here's a peek at what's inside 1️⃣ Exploratorium and Gladstone Bring a Breakthrough Science Exhibit to Life 2️⃣ Scientists Use Cancer’s Strength to Fight Against It 3️⃣ Meet Gladstone: Alicer Andrew Plus our latest publications, features in the news, and much more!
Cell Signals│Exploratorium and Gladstone Bring a Breakthrough Science Exhibit to Life
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"Abstract The identification of immunogenic peptides has become essential in an increasing number of fields in immunology, ranging from tumor immunotherapy to vaccine development. The nature of the adaptive immune response is shaped by the similarity between foreign and self-protein sequences, a concept extensively applied in numerous studies. Can we precisely define the degree of similarity to self? Furthermore, do we accurately define immune self? In the current work, we aim to unravel the conceptual and mechanistic vagueness hindering the assessment of self-similarity. Accordingly, we demonstrate the remarkably low consistency among commonly employed measures and highlight potential avenues for future research."
A journey to your self: The vague definition of immune self and its practical implications | Proceedings of the National Academy of Sciences
pnas.org
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Truly comprehensive, differentiated AI foundation models for human cellular and tissue biology are a material breakthrough for advancing anti-cancer and related therapies Great to see this progress from DCVC-backed NOETIK
NOETIK is excited present results using our first-in-class foundation models of cell and tissue biology this Friday at #SITC24. Lacey Padrón (abstract #1231) will share a full stack view of our platform from data to discovery: https://lnkd.in/g2dXFthr Yu (Phoebe) G. (abstract #861) will share our work using multimodal foundation models to study the biology of Tertiary Lymphoid Structures (TLS): https://lnkd.in/g7c9uhyE For partnering/collaboration discussions, connect live with Shafique Virani, MD FRCS. https://lnkd.in/gpHCDpmn
Noetik Announces First-in-Class Human Foundation Models for Discovery at SITC 2024
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Seminar tomorrow - what changes can we make to the assessment of grant applications to remove barriers for marginalised researchers?
On 23 April we hosted a panel discussing peer review bias. The data shows that peer review does not produce the meritocracy commonly believed in academia. You can watch the recording on our website. On 22 May we host a follow-up panel of funders and researchers discussing what are the alternatives to classic peer review? For more information and to sign up for free to attend on 22 May 10-11:30 BST: https://lnkd.in/dFf5gsgP Royal Society of Chemistry Royal Geographical Society - with IBG ǀ Venue Hire Royal Society of Edinburgh Learned Society of Wales The British Academy Women in STEM Australia Cancer Research UK (CRUK) Research On Research Institute (RoRI) Wellcome Trust Wellcome Sanger Institute The Royal Society ARMA UK (Association of Research Managers and Administrators) NIHR (National Institute for Health and Care Research) Scottish Funding Council
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Have you heard about CSHL's Innovators Symposium 2025? Whether you're a senior grad student or there is an up-and-coming cancer biologist or neuroscientist in your life who comes to mind, this is a chance to present research, network with CSHL experts, & lay the foundation for your career. Funding included—don’t miss this chance! Applications must be submitted by Nov 22, 11:59 PM ET. https://bit.ly/48D7IIb
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One from today. Come listen to the conversation about what methods could make research & innovation funding more fair.
On 23 April we hosted a panel discussing peer review bias. The data shows that peer review does not produce the meritocracy commonly believed in academia. You can watch the recording on our website. On 22 May we host a follow-up panel of funders and researchers discussing what are the alternatives to classic peer review? For more information and to sign up for free to attend on 22 May 10-11:30 BST: https://lnkd.in/dFf5gsgP Royal Society of Chemistry Royal Geographical Society - with IBG ǀ Venue Hire Royal Society of Edinburgh Learned Society of Wales The British Academy Women in STEM Australia Cancer Research UK (CRUK) Research On Research Institute (RoRI) Wellcome Trust Wellcome Sanger Institute The Royal Society ARMA UK (Association of Research Managers and Administrators) NIHR (National Institute for Health and Care Research) Scottish Funding Council
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