Oriental Journal of Chemistry’s Post

-To Analyse Rhodium Normax complex and impurities. #normalbutanol #rhodium #normax #HPLC #GLOVEBOX #Quality control #Chemist #chemistry

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Gas chromatography method development

🚀 Join Us for a Live Webinar Register here: https://lnkd.in/gQyi8M-K 𝐋𝐞𝐯𝐞𝐫𝐚𝐠𝐞 𝐌𝐢𝐱𝐢𝐧𝐠 𝐀𝐧𝐚𝐥𝐲𝐬𝐢𝐬 𝐟𝐨𝐫 𝐑𝐢𝐠𝐡𝐭-𝐟𝐢𝐫𝐬𝐭-𝐭𝐢𝐦𝐞 𝐒𝐜𝐚𝐥𝐞-𝐮𝐩 𝐒𝐮𝐜𝐜𝐞𝐬𝐬 Date: 18 April 2024 Time: 10 AM GMT 𝐖𝐞𝐛𝐢𝐧𝐚𝐫 𝐀𝐠𝐞𝐧𝐝𝐚: 🔬 Comparing mixing parameters across the scales 💰 Automated CFD Analysis to reduce loss of yield by 30%  💹 Case Studies: Scale-up of fast reaction, crystallization, etc Scale-up of chemical processes such as mixing sensitive reactions and crystallization processes in stirred tank reactors can many times go wrong due to the limitations of mixing correlations such as mismatched geometric similarity and experimental conditions under which the correlations are applicable.  A user-friendly CFD-based software MixIT allows a process engineer to accurately calculate and compare mixing parameters across the scales and select the most appropriate reactor and/or implement necessary changes in the agitator design, identify the most suitable dosing location to replicate the mixing environment from lab/ pilot plant to production scale.  This webinar shares case studies of mixing scale-up for a liquid-liquid heterogeneous fast oxidation reaction, a low occupancy antisolvent crystallization process to replicate particle size, selection of dosing location in an antisolvent crystallization process to improve particle size and hence filtration time and site-to-site process transfer for a liquid-liquid heterogeneous reaction. The selection of mixing scale-up parameters and use of three-dimensional analysis of velocity, turbulent energy dissipation rates and calculation of droplet size distribution and mesomixing time distribution is demonstrated in the case studies to ensure successful scale-up. Uttamkumar Joshi Gopal Kasat Dipak Kainchi Nikhil Patil Ketan Bais Tridiagonal Solutions #chemicalindustry #pharmaindustry #pharmamanufacturing #chemicalmanufacturing #chemicalmaufacturer #scaleup #processdevelopment #foodandbeverage #foodandbeverageindustry #mixit #mixing #mixingtechnology #europe #processindustry #processoptimization #workshop #event #chemical #chemicalindustry #pharmaindustry  #chemicalmanufacturing #processengineering #dublin #dublinireland #ireland #apc #lifesciences #lifescienceindustry #ceo #processengineer #founders #scaleup #drugdesign #biopharmaceuticals #pharmaceuticalmanufacturing #api #drugdevelopment #biologics #biopharmaceuticals #foodandbeverage #foodandbeverageindustry #foodandbeveragemanufacturing #cdmo

𝐓𝐡𝐞 𝐂𝐨𝐦𝐩𝐥𝐞𝐭𝐞 𝐆𝐮𝐢𝐝𝐞 𝐭𝐨 𝐇𝐢𝐠𝐡-𝐏𝐞𝐫𝐟𝐨𝐫𝐦𝐚𝐧𝐜𝐞 𝐋𝐢𝐪𝐮𝐢𝐝 𝐂𝐡𝐫𝐨𝐦𝐚𝐭𝐨𝐠𝐫𝐚𝐩𝐡𝐲 (𝐇𝐏𝐋𝐂) 𝐃𝐨𝐰𝐧𝐥𝐨𝐚𝐝 𝐏𝐃𝐅 𝐂𝐨𝐩𝐲 - https://lnkd.in/deJuaPAp   High performance liquid chromatography (HPLC) is mainly a highly improved form of column chromatography. It is a chromatographic technique which is used for separating the components in a mixture, to identify each component, and to quantify each component.   #hplc #chromatography #laboratory #chemistry #cromatografia #cannabis #canna #laboratorio #quimica #science #carp #fishing

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GC (Gas Chromatography) principle: GC separates and analyzes the components of a mixture based on their boiling points, affinity to a stationary phase, and molecular interactions. Key components: 1. Injection port: Sample introduction 2. Column: Separation occurs in a narrow tube with a stationary phase 3. Carrier gas: Inert gas (e.g., helium, nitrogen) that transports the sample 4. Oven: Temperature control for separation optimization 5. Detector: Measures the components' presence and quantity GC principle steps: 1. Vaporization: Sample is converted to a gas 2. Separation: Components interact with the stationary phase and separate based on boiling points and affinity 3. Detection: Components pass through the detector, generating a signal 4. Data analysis: Chromatogram generation and component identification GC is used in various fields, including: - Pharmaceutical analysis - Environmental monitoring (e.g., air, water quality) - Food safety and quality control - Forensic science - Petrochemical analysis GC types: - Gas-Liquid Chromatography (GLC) - Gas-Solid Chromatography (GSC) - Capillary GC - Preparative GC.

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