Origins - The Patient Focused Specialists’ Post

Should be an interesting webinar from our Origins - The Patient Focused Specialists colleagues. More details below

Advancing the Fight Against AIDS Through Clinical Research On this #WorldAIDSDay, we honor the groundbreaking strides made through clinical research in the global fight against HIV/AIDS. Clinical trials have paved the way for life-saving therapies, transforming what was once a devastating diagnosis into a manageable condition for millions. These advancements would not be possible without the tireless efforts of researchers, healthcare professionals, and the bravery of trial participants. Organizations like the Bill & Melinda Gates Foundation and other NGOs and philanthropies have played a pivotal role in funding research and making therapies accessible to underserved communities worldwide. While we’ve come far, the journey is not over. Continued investment in clinical research is vital to reach the ultimate goal: a world free of AIDS. At Clinical Research Learning Network we are proud to champion the power of clinical trials in driving medical breakthroughs. Together, we can continue to make a difference. #WorldAIDSDay #ClinicalResearch #HIVAwareness #EndAIDS #MedicalAdvancements #GlobalHealth #ResearchMatters #CRLN What are your reflections on this day? Share your thoughts below!

Pleased to see this brief report finally published. We examined the association between rheumatic disease therapies and cardiovascular outcomes in a cohort of veterans with HIV in Atlanta. More studies are needed to understand the intersection of rheumatic diseases and HIV. #HIV #comorbidities

1. **Study Overview**: A pilot study by UT Health San Antonio suggests the HIV drug lamivudine may help control some effects of Alzheimer’s disease. 2. **Clinical Trial Results**: The study showed significant improvement in participants with mild cognitive changes after six months of treatment with lamivudine. 3. **Mechanism**: Lamivudine appears to reduce neurodegeneration and inflammation associated with Alzheimer’s. 4. **Participant Demographics**: The trial involved 12 participants aged 52 to 83 who exhibited mild cognitive symptoms. 5. **Next Steps**: Researchers plan to conduct a yearlong study with a larger group to further validate the findings against a placebo. 6. **Safety and Efficacy**: The treatment was deemed safe, with potential benefits for individuals with early Alzheimer’s disease. 7. **Importance of Early Detection**: Advances in biomarker identification and brain imaging enhance early detection of Alzheimer’s, allowing for timely treatment. 8. **Lifestyle Recommendations**: A. Campbell Sullivan advises at-risk individuals to maintain a nutritious diet, engage in stimulating activities, ensure deep sleep, and exercise regularly to manage Alzheimer’s risk.

On this World #AIDS Day, the International Antiviral Society–USA Panel has released updated guidelines for HIV treatment and prevention, published in JAMA, and co-authored by Rajesh Gandhi, MD, and colleagues from Massachusetts General Hospital. World AIDS Day serves as an important reminder that we must remain steadfast in our commitment to prevent new HIV infections and provide essential services to all people living with HIV globally. These recommendations highlight the different treatments and prevention strategies for the disease, while also emphasizing the importance of addressing care disparities to ensure equitable access and progress toward ending the HIV epidemic. Read more: https://lnkd.in/gMy8B8_B #WorldAIDSDay #HIVCare #PrEP #EquityInHealth #MassGeneral #HIV

Check out the latest eHIV Review: Navigating HIV in the Aging Population: Advanced Clinical Insights. This issue addresses the unique challenges faced by older adults living with HIV, including cardiovascular disease risk, polypharmacy, and cognitive impairments. Dr. Jose A. Lucar from The George Washington University offers insights into cardiovascular risk reduction and tailored strategies to manage these complexities. Enhance your ability to assess and manage factors impacting the treatment of older PLWH.https://buff.ly/3xQndyr

TARGET REVIEW ON CCR5 Therapeutic area is Stroke Semester 1 Where I spoke about how CCR5 helps for stroke as it was a evidentiary receptor for HIV In a brief absence CCR5  Neurons Will Make A New Connections So while Stroke makes your part of a brain dead , severing those cells the connection with neurons in other regions will be disconnected so decline of CCR5 will help neurons to regain they disconnected abilities . We can develop a therapy by using it

Combined antiretroviral drugs (cART) have improved outcomes for people living with HIV. Still, these drugs are associated with comorbidities, for example, (abnormal weight gain, and increased risk of cardiovascular diseases) that undermine the success of the drugs. Mitochondrial DNA (mtDNA) background might be able to explain which groups are more at risk for these comorbidities. Here the authors showed in treatment-naive subjects that those carrying the European haplogroup UK mtDNA exhibit lower weight gain following cART initiation, irrespective of cART, compared to the other Eurasian sub-haplogroups. https://lnkd.in/e3QybRmC #HIV #cART #Mitochondria #haplogroup

🌍 𝐖𝐨𝐫𝐥𝐝 𝐀𝐈𝐃𝐒 𝐃𝐚𝐲 – 𝐃𝐞𝐜𝐞𝐦𝐛𝐞𝐫 𝟏𝐬𝐭 🌍 Today, we recognize World #AIDS 𝐃𝐚𝐲, a vital opportunity to raise awareness, support those living with HIV, and remember those who have lost their lives to AIDS-related illnesses. This year, we're shining a spotlight on the often-overlooked role of urology in the diagnosis, management, and treatment of HIV/AIDS. 👨⚕️ 𝐖𝐡𝐲 𝐔𝐫𝐨𝐥𝐨𝐠𝐲? HIV can have significant urological complications, including infections, kidney disease, and even cancers. Early detection and specialized care by urologists play a critical role in improving patient outcomes and quality of life. Throughout December, we’ll be sharing insights, expert opinions, and success stories to highlight the importance of multidisciplinary care in addressing HIV/AIDS. Together, let's work towards a future where early diagnosis and comprehensive care help transform lives. Optima Clinic - Centrum Medyczne Clinic - Centrum Medyczne#WorldAIDSDay #Urology #HIVAIDS #Healthcare #PatientCare #EarlyDetection #MultidisciplinaryCare #HIVAwareness #UrologicalHealth