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WONDERMIND.COM FRANCOISE BETTENCOURT MEYERS L'OREAL HEIRESS c/o ODEON RESTAURANT TRIBECA NY WHAT'S ON THE TABLE UPSTAIRS.? I HOPE NY HAMPTON BEACH HOUSE.! LATE JOSE' CHEF & LOUIE BERKSHIRE HATHAWAY WARREN BUFFET Chairperson MAYE MUSK Supermodel. E. MUSK. Mother BILL & MELINDA GATES FOUNDATION GATESFOUNDATION.org Tenri.org TENRI CULTURAL INSTITUTE GALLERY SPRING THEME Cryptocurrency REYGITONIUM-G https://lnkd.in/e55sRd8b https://lnkd.in/eB98Jnv9 WonderMind.com WHAT'S ON THE TABLE*Crypto-REYGITONIUM-G MR. MS. TEEFEY & SELENA GOMEZ-RARE-SUPERSTAR TO WHOM IT MAY CONCERN I ABSOLUTELY SEE NOTHING WRONG WITH CRYPTO-REYGITONIUM-G I CAN UNDERSTAND WHY THE INFANT DEMOCRATIC-CAPITALISTIC MINDS BLAME USA GOVERNMENT. THEN IS ANY GOVERNMENT TO BE BLAMED FOR HOMELESS PROBLEMS PLAGUING THE WORLD.? NO. GOD KNOWS HEADACHES US GOVERNMENT HAVE WITH THE FOREIGN AFFAIRS. THE NEW WORLD TRUE SHOCK TO WITNESS. PEOPLE WORKING TOGETHER FOR A COMMON GOAL. IN THE PURSUIT OF HAPPINESS. DOESN'T THAT ALSO INCLUDE THE HOMELESS. THE HOMELESS ARE OUT THERE. ARE YOU.? HOMELESS.. OPPORTUNITY MISUNDERSTOOD. The modern economic system is a market economy, which is a capitalist economy where people, not the government--NOT THE GOVERNMENT--own most businesses. In a capitalist economy, prices allocate capital and labor between competing uses, and capital assets can be privately owned and controlled. GOOGLE https://lnkd.in/eB98Jnv9 EXAMPLE IF YOU NEED TO RAISE MONEY FOR ANY REASON OR LETS SAY THE "HOMELESS PROBLEM WHICH IS BELIEVED TO BE TIME & MONEY CONSUMING BUT IN ONE DIRECTION TOWARD THE HOMELESS. HOWEVER CRYPTOCURRENCY CAN POSSIBLE ALLOWS AN EXPENDITURE OF CRYPTOCURRENCY TO BENEFIT ALL WHO USES THE CRYPTO & REGARDLESS OF HOW IT'S CONSUMED. THEREFORE IF A CRYPTO-CURRENCY REYGITONIUM-G EXISTED IT'S MORE HIGHLY LIKELY THE HOMELESS PROBLEM CAN BE VANQUISHED BECAUSE FINANCES WILL ALWAYS BE AVAILABLE TO BE TAPPED INTO FOR HOMELESS RESOLUTIONS. REYGITONIUM-G: EACH COUNTRY GOVERNMENT INITIAL $1-DOLLAR INVESTMENT PORTFOLIO OF 8-BILLION EARTH CITIZENS. THEREAFTER GLOBALLY ANYBODY CAN INVEST IN THE CRYPTO-REYGITONIUM-G. FAMILY SECURITY. OR CONTINUE HIDING THE HOMELESS WHEN A POLITICAL LEADER VISITS AMERICA. CLOSING COMMENT: THE DAMNEDEST CRAZIEST FUNNIEST EMBARRASSING ABOUT THE HOMELESS CHAOS IS ANY EXCUSE AS TO WHY HOMELESS EXIST. HENCEFORTH CONSIDER USA TRILLIONS IN DEBT & 6,120 HOSPITALS SCATTERED AROUND THE USA & MANY COUNTRIES ASKING FOR FOREIGN AID IN THE TRILLIONS & YOU TALKING EXCUSES. MEANWHILE WE WANT TO SETTLE HUMANITY ON OTHER PLANETS. THANK YOU FOR READING.

  This chapter describes the production of #LNP-encapsulated, nucleoside-modified, and purified mRNA and the evaluation of antigen-specific T cell and antibody responses elicited by this vaccine form. https://lnkd.in/e5Q66d4f

For biotech marketers and CEOs, keeping pace with groundbreaking research that could lead to new product opportunities is a constant struggle. The sheer volume of scientific literature can be overwhelming, making it difficult to identify truly transformative developments. Our latest article spotlights fascinating immunological advancements, such as Natural Killer (NK) cell-based immunotherapy and RNA vaccines. We explore how this research could revolutionize drug development and therapeutic strategies, potentially leading to more effective, personalized treatments. Expand your understanding of this cutting-edge field and its implications for the biotech industry: https://hubs.li/Q02T9b_D0 #PersonalizedMedicine #BiotechInnovation #DrugDevelopment #RNAvaccines #Immunology #Immunotherapy

💉 How does LNP size affect vaccine performance? 👩🔬 In "Impact of lipid nanoparticle size on mRNA vaccine immunogenicity”, Kimberly Hassett and colleagues from the Moderna team took a systematic approach to modifying the particle size of #mRNA-#LNPs #vaccine formulations encoding for a cytomegalovirus surface pentamer complex and for envelope glycoprotein gB by adjusting formulation process variables while keeping lipid composition constant. 🔬 #CryoEM nicely confirmed the intended increase in particle size as measured by NTA and DLS. Furthermore, cryo-EM images showed a wider size range as well as the presence of #multilamellar structures in the larger particle formulations. The particle surface was found to be less polar with increasing size, and after showing that total mRNA encapsulation did not correlate with LNP size measurements, the impact of LNP size on innate immunogenicity in mice and non-human primates was studied. 🧪 The researchers show that in mice LNPs smaller than 85–100 nm induced significantly lower immunogenicity with respect to the size interval of 100–200 nm, whereas in non-human primates all tested LNPs in the 60-150nm size range triggered a strong immune response when the LNPs were delivered intramuscularly, suggesting species-specific differences in LNP size sensitivity. 📑 Read the study: https://lnkd.in/gu4fgxTs 👉 Learn more about phase appropriate characterization of #lipidnanoparticles: https://lnkd.in/g5s7Pk7z

FYI: 5 Advantages of mRNA Vaccines 1. Safety: No risk of evolution/resurgence, mutation/recombination, or integration into host genome. 2. Cellular Immune Response: More comprehensive, stronger and durable immune response. 3. Short R&D cycle: DNA sequence to mRNA/LNP only takes 2 months. 4. Easy to Scale Production: The mRNA manufacturing process does not involve cells, and one liter of IVT reaction can generate 100,000 doses. 5. Multivalent Vaccine Possible: Different mRNA sequences can be encapsulated in a single LNP. Have any questions on how to develop mRNA vaccines? We are happy to help you. Get in touch with us at sales@areterna.com #mRNA #vaccines #IVT #LNP

The authors of this paper investigated and reported which cell types LNPs stimulate and show immunostimulatory activity. They prepared empty LNPs without mRNA using the ionizable lipid used in the marketed Corona vaccine, added them to several cell types in vitro, and evaluated the chemokines produced by these cells. The results showed that lymphatic endothelial cells (LECs) produced chemokines involved in the recruitment of monocytes/neutrophils. This suggests that LECs would act as the first signaling cells in response to LNP. https://lnkd.in/efSesxSW #LNP, #lipidnanoparticles, #stimulate, #immunostimulatory, #ionizablelipid, #mRNA, #LEC

𝐒𝐚𝐯𝐞 𝐄𝐯𝐞𝐧 𝐌𝐨𝐫𝐞 𝐨𝐧 𝐇𝐢𝐠𝐡-𝐐𝐮𝐚𝐥𝐢𝐭𝐲 𝐂𝐒𝐓® 𝐀𝐧𝐭𝐢𝐛𝐨𝐝𝐢𝐞𝐬 CST economically bundles antibodies in Antibody Sampler Kits and Antibody Duets. You can save even more now. Use code 𝐀𝐏𝟏𝟓𝐀𝐒𝐃𝟐𝟒 and get 15% off when placing your order till June 15th. • Antibody Sampler Kits: A convenient kit including a range of targets (3-9, 20μl) to cover a key cellular event. Broaden your scope for a great price. • Antibody Duets: The total and modified antibody bundled in one kit. Superior quality for a great price. . To know more write to us at inquiry@zellebiotech.com . #zellebiotechnology #biotechnology #antibodies #CARTtherapy #Immunotherapy #Immunology #CancerResearch #cellsignaling #cellbiology #proteomics #antibodies #proteins #ihc #antigen

Messenger RNA (mRNA) vaccines have great potential for the treatment of human diseases. However, problems such as the production of reactive oxygen species during mRNA translation can greatly affect translation efficiency, which in turn limits the application of mRNA vaccines. In view of this, researchers have developed a new strategy to significantly improve the efficacy of mRNA vaccines by promoting mRNA translation and stimulating the activation of interferon genes (STING). https://lnkd.in/gUDCCJt8

🧬 Presenting the Magic of mRNA Vaccines: 5 Mind-Blowing Facts! 🚀 Did you know: mRNA vaccines teach our cells to make proteins, not the virus itself! 🦠 They can be developed in a lab using readily available materials 🧪 Production is faster than traditional vaccines - sometimes in weeks! ⏱️ They don't enter the nucleus of our cells or alter DNA 🧬 The technology behind them has been studied for decades! 📚 These vaccines are revolutionizing how we fight diseases. From COVID-19 to potential cancer, the future of medicine is here! 💡 What other potential applications of mRNA technology excite you? Share your thoughts below! #mRNAVaccines #BiotechInnovation #FutureOfMedicine #VaccineScience #HealthTech

🌟 Don’t miss us at the EMBRN Congress! 🌟 We are delighted to share that Genoskin will be presenting a groundbreaking poster and oral presentation at the European Mast Cell and Basophils Research Network (EMBRN) Congress in Toulouse. Join us from May 29-31 to explore our latest research! 🔬 Spotlight on Our Presentation: “Single cell profiling of biostabilized natural human skin identifies mast cells as an important target of injected mRNA-1273 COVID-19 vaccine” Join us on May 30, 2024 at 2:45pm as Katarzyna Polak reveals cutting-edge #research that highlights the crucial role of #mastcells in the #immuneresponse to vaccine injection. Utilizing our bioengineered human skin model, we provide an innovative perspective on how the human skin ecosystem reacts to the mRNA-1273 COVID-19 vaccine. Interestingly, we discovered that mast cells, alongside DC/macrophages, show a natural affinity for integrating #vaccine mRNA. 🔗 Learn more about the immune response to vaccines here: https://bit.ly/4dH8Ywf. Join us to discuss our findings and explore potential collaborations. Discover how our insights can aid in developing safer, more effective vaccines with direct translational relevance. See you at EMBRN 2024!