Postdoctoral Affairs at Case Western Reserve University’s Post

Our Translational Ophthalmology community, led by our Chief Editor Leo Kim, PhD, is issuing an open submission call! 🔉 The community edition "Epithelial-Mesenchymal Transition (EMT) and Myofibroblast Transdifferentiation in Eye Diseases" will be led by editor Daisy Shu, PhD, and seeks research exploring the role of EMT and myofibroblast transdifferentiation in eye diseases, covering original research, clinical trials, reviews, and more. 🌍 Global submissions are welcome with an article processing charge of $750. Submission language: English Candidate profile: Experts in ophthalmology, cell biology, and related fields. Register and submit your manuscript: https://lnkd.in/djPNVu7x Review the criteria here: https://lnkd.in/d8TXahWw #ophthalmology #CellBiology #EMT #MedicalResearch #academia #science #eyediseases #clinicaltrials

Whitney A. Stevens-Sostre, PhD, has received the prestigious Hannah Gray Fellowship from Howard Hughes Medical Institute. Stevens-Sostre is a postdoc in the laboratory of Mrinalini Hoon, PhD, associate professor of ophthalmology and visual sciences. Stevens-Sostre investigates how distinct populations of voltage-gated ion channels — integral membrane proteins that detect changes in voltage and regulate the flow of ions — shape the stimulus responses, connectivity and intrinsic excitability of retinal neurons. To learn more: https://buff.ly/4fWEfLs

Cynthia Owsley, PhD, Gerald McGwin, Jr., PhD, and fourth-year resident Poojitha Balakrishnan, MD, PhD, MPH validated timed instrumental activities of daily living (TIADL) tasks as an objective measure for adults with irreversible vision impairment in their recent BMC Ophthalmology article "Timed instrumental activities of daily living tasks in adults with irreversible vision impairment: validation to visual function and self-report." Their study involved 88 patients from UAB’s Department of Ophthalmology and Visual Sciences and found that longer task completion times correlated with decreased visual acuity, contrast sensitivity, and visual field. TIADL scores were also significantly associated with self-reported abilities in reading-related tasks, making TIADL a valuable complement to self-reported measures in clinical and research settings. Read more: https://lnkd.in/eQZGzd5R

We, at Femtonics, are very proud of our partners, leading experts in neuronal network research, who presented at the recent 𝐒𝐲𝐦𝐩𝐨𝐬𝐢𝐚 event at the Federation of European Neuroscience Societies - FENS on June 26th. Thank you to all who attended and made this event a great success! 👏 From Botond Roska's presentation, we learned that he and his lab have developed a two-photon imaging method using 3D acousto-optical microscopy to study the development of cortical circuits in living mouse embryos, revealing that Rbp4-Cre neurons form distinct, active, multi-layered circuits that switch configurations during embryonic development. Attila Losonczy has provided an overview of their recent efforts to investigate spatial and temporal rules of learning-related plasticity in the hippocampus of behaving mice using all-optical methods with 3D acousto-optical scanning for synaptic plasticity induction and read-out. Bradley Rauscher's lecture covered recent advances in neurophotonic technologies to study spontaneous neuronal and neurovascular activity in the mouse cerebral cortex, focusing on tools like two-photon imaging and optically transparent electrode arrays to understand neurovascular coupling and infer neuronal activity from noninvasive imaging signals. And finally, Balázs Rózsa presented 𝐌𝐨𝐜𝐮𝐥𝐮𝐬, a new immersive virtual reality platform enabling ~100-300-fold faster visual discriminative learning. He also revealed novel network mechanisms discovered during learning. 📢 He also introduced a groundbreaking development from BrainVisionCenter: the world's first 𝐅𝐑𝐄𝐄𝐋𝐘 𝐌𝐎𝐕𝐈𝐍𝐆 3𝐃 𝐌𝐈𝐂𝐑𝐎𝐒𝐂𝐎𝐏𝐄, which allows fast 3D acousto-optical scanning (>100 kHz/ROI) with high resolution in large scanning volumes, even in freely moving mice. 🔬

Make sure to claim your spot for this interesting lunch & learn session of the UM data science research seminar series!

I’m thrilled to share that our latest study, "Myopia and Systemic Manifestations of Tissue Hyperlaxity: A Population-Based Cross-Sectional Study," has been published in Clinical and Experimental Ophthalmology! In this research, we explored the association between myopia and systemic signs of connective tissue hyperlaxity among adolescents. Our findings, based on a large cohort of over 920,000 adolescents, show that those with myopia had a higher prevalence of conditions like hernias, pes planus, and scoliosis, potentially indicating a link between myopia and systemic tissue laxity. These insights could pave the way for further exploration into the pathophysiology behind myopia formation and progression. You can find more details here: https://lnkd.in/dkRFg46P. A big thanks to my co-authors Idan Hecht and Itay Nitzan for their dedication to this project! #Research #Ophthalmology #Myopia

📌Volume 76 No. 2 (2024) published (https://lnkd.in/dcKCPpuS) 📄This issue of the journal focuses on several actual areas of modern medicine, including rehabilitation, mental health, oncology, immunology, infectious diseases, neurology, dentistry, and gynecology. 🦾It also addresses urgent topics related to the impact of war, as reflected in some studies, for instance, "Revision Surgery for Amputation Stump Terminal Neuroma After Blast Injuries" and in the review "Methods for Assessing the Size and Depth of Burn Wounds." ✒️The historical section provides valuable insights into the contributions of prominent figures of Lviv National Medical University 'Danylo Halycky' , reports from recent scientific events, including "Doctors and Nursing: Transformation in The Conditions of War and Continuous Recovery" and "Smart Lion. War in Ukraine: Medical Response." 📚This edition also features brief communications and articles exploring the future of medical education and healthcare, with contributions of scientists from all around the world. Additionally, the history and current collaborations between the anatomical departments of universities in Vienna, Krakow, and Lviv is demonstrated. We sincerely thank all the Аuthors for their invaluable contributions to advancing medical science and supporting the growth of Ukrainian research.💛💙 #MedicalResearch #AcademicExcellence #EasternEuropeMedicine #PeerReviewed #MedicalSciences

🌟 Highlighting a Pioneer in Neuroscience: #Jean_Pierre_Changeux 🌟 Today, we celebrate the groundbreaking contributions of Jean-Pierre Changeux, a distinguished neuroscientist renowned for his work on nicotinic acetylcholine receptors (nAChRs). His research has significantly advanced our understanding of neurotransmitter signaling and its impact on brain function and behavior. Changeux’s discovery and characterization of nAChRs not only unraveled the mechanisms of nicotine’s effects on the brain but also opened new doors to understanding synaptic plasticity, neurodevelopment, and neurological disorders. His interdisciplinary approach has bridged the gap between molecular biology, pharmacology, and cognitive neuroscience. 🔬 His work has inspired countless innovations in: ✔️ Neurological disease treatment (e.g., Alzheimer’s and Parkinson’s). ✔️ Addiction research and therapy development. ✔️ Exploring the molecular basis of consciousness and learning. Let’s honor his legacy and continue to explore the complex yet fascinating world of neuroscience, inspired by his pioneering vision! #Neuroscience #JeanPierreChangeux #NicotineReceptors #MolecularBiology #BrainResearch Thanks Sudherson M Head of fovea-Z PH. +918807039891 WWW.ATHEENAPANDIAN.COM I thank CEO Dr S. ATHEENA MILAGI PANDIAN, Rashika Murugan mam and our team Varma V, MOHAMMED SAHIL S, Sri Manoj Kumar and Kriya Sakthi M, Dhanushya S,Aruna V and Krithina Dharmarajan for their continuous support. Our Zonal and Regional Representative Dhanushika Pappannan, Teja Sri, Harish Selvakumaran, Ahamed Wassaf, SANJAY P, Gokulraj R, and Vishwanathan Reddy ATHEENAPANDIAN - India's No.1 Biomedical Industry for Training & Placements | International fovea-Z Biomedical (IFB) | Head of Biozeephysis | Biomedourse | Head of fovea-Z | VICE PRESIDENT - ATHEENAPANDIAN | Srilankan Society Biomedical Science Team. we would like to thank all the biomedical associations and education institute India Slovenia Alliance for Education, Trade and Culture World Education Fair Slovenia Institute of Biomedical Engineering Biomedical Engineering Technology Society Ministry of Foreign Affairs Slovenia Ministry of Finance of the Republic of Slovenia Biomedical Engineering Society MSOE Biomedical Engineering Biomedical Engineering Summit Neurosurgery Research and Education Foundation (NREF) NeuroSurgery.academy Johns Hopkins Department of Neurosurgery

4500 downloads in 9 weeks! Davis Joseph article live statistics at the link below: https://lnkd.in/dJ9SHV_p Just for comparison: Among a total of 320 articles with assigned DOIs published in The Archives of Plastic Surgery (APS) during a two-year period (2012-2013) accessed through the DOI proxy server from January 2012 to March 2014 : One paper was accessed more than 199 times; four papers 100-199 times; 6 papers 50-99 times; 22 papers 30-49 times; and 106 papers 1-29 times. (https://lnkd.in/dcKPRSej) Davis Joseph article is a record in numerous directions: - never an single author article has had so much download for such a short period of time. - as a single author article the author did himself the discovery, and experimental validation and developed some new techniques - ⁠the number of single authors publications in 2020 are at 0.43 % of all research articles published (https://lnkd.in/dz7_V5Vp Fig. 5B and Table 3). Today most of the articles are with multitude of authors like this one that has 85 authors ( https://lnkd.in/dUA6vXx3). The champion number of authors in one article is 5,154. They are all authors of this article: https://lnkd.in/dkdQp3cA Davis Joseph single-author article with 4500 downloads in 44 days describes the breakthrough discovery linked to the curing of Alzheimer’s and Parkinson’s diseases published by our 2024 Award Winner Davis Joseph at the International Journal of Molecular Sciences, one of the world’s top journals in the fields of Biochemistry and Molecular Biology (a Q1 Journal). The full paper is given here: https://lnkd.in/dJ9SHV_p The live statistics can be seen at the end of the above linked page. For this breakthrough discovery Davis Joseph was Awarded at FLOGEN SIPS 2024 the Semenza International Cell Engineering in Medicine Award for this Discovery. The award was personally handed over to Davis by Prof. Gregg Semenza, 2019 Nobel Laureate in Medicine, C. Michael Armstrong Professor of Genetic Medicine, Johns Hopkins University School of Medicine and director of the vascular program at the Johns Hopkins institute of cell Engineering, USA #sips2024 #flogensips #flogen #flogensustainabilityframework #danshechtman #technology #sustainability #crete #greece #agiapelagia #outoftheblueresort #DavisJoseph #Alzheimer #Parkinson #deamidation #4EBP2 #axons Davis Joseph

🎉 Exciting News from us! 🎉 Our new publication at ACS Publications A new approach to neural rehabilitation! We're thrilled to share our latest publication in the field of neural rehabilitation—a realm fraught with challenges, including significant disability and limited recovery options. Our research has taken a promising step forward with the study of rare-earth metal-based upconversion nanoparticles (UCNPs). These nanoparticles have shown incredible potential in driving the differentiation of PC-12 cells into neurons and enhancing primary mouse neurogenesis. Key findings from our study: - UCNPs significantly increased neural length and quantity in primary mouse models. - In experiments with primary neural stem cells, UCNP treatment not only boosted the expression of the neuronal marker TUBB3 but also curtailed differentiation into astrocytes. - In prolonged experiments, UCNPs enhanced the stability of neuronal axons and facilitated the establishment of intercellular connections. This breakthrough highlights the remarkable potential of UCNPs to not only promote neuronal differentiation and sustain axonal growth but also to stabilize and enhance intercellular connections at the cellular level. We are excited about the implications of our findings for advancing neural rehabilitation and eagerly anticipate further developments. #NeuralRehabilitation #Neuroscience #Innovation #ResearchImpact