Pharmacy Group Journals’ Post

https://lnkd.in/gbkjiSaq Article Title: Glass Delamination in sterile formulations and Drug Recalls: A Review Author(s): Kabirdas B Ghorpade* and Sharda M Shinde Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Abstract: Injectable formulations are constantly facing continuing challenges of glass compatibility. To assure glass compatibility of the injectable formulation in the area of current interest. Most of the common and serious challenges of glass compatibility are glass delamination. Glass delamination is basically the degradation of the glass and formation of the flakes as a result of the incompatibility with the product stored. The other factors which contribute to glass delamination are the Type of glass container used, Storage condition, and Pharmaceutical Processings like terminal sterilization. Glass delamination should be taken very seriously as it is when present in the formulations it is directly related to the health of the patient. This review describes the Factors responsible for the glass delamination and its effect on patient health and the quality control analysis techniques of the same. #Glassdelamination #Terminalsterilization #Hydrolyticresistance #SEM #TEM #Drugrecalls #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation#DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials

#Genotoxic impurities are compounds that can cause damage to DNA, potentially leading to cancer and other health risks. As a #pharmaceutical company or #CDMO, it is crucial to identify and quantify these #impurities to ensure that APIs, #excipients and formulations are safe and comply with #regulatory requirements. Join our Fireside Chat on April 24 to learn more on genotoxic impurities and how they affect the safety of medicines. In this interactive discussion Evonik's experts Michael Nonnenmacher, Daniel B., Jürgen Volz and Elizabeth White draw on their experience in #toxicology, #analytics, regulatory affairs and business development to address the latest trends and challenges in genotoxic impurity testing. The session is highly relevant to anyone working in #API clinical stage development, research, process development or #outsourcing at pharmaceutical and generic drug makers. Learn about the interdisciplinary approach needed to navigate the complex landscape of genotoxic impurities and make medicines safer for patients. To learn more and save your seat for the event please visit https://lnkd.in/eU2XbrHe. #webinar #gti #nitrosamines #m7 #hpapi #drugsubstance #cmo #contractmanufacturing #biopharma #pharma #healthcare #webcast

Want to learn more about Genotoxic Impurities? Come join our Evonik experts for a fireside chat with on this important topic. hashtag #genotoxic #gti #Evonik #API #webinar

🔍Come find us! 🦠Today marks day 1 of PDA - Parenteral Drug Association's Pharmaceutical Microbiology Conference 2024. Novatek International's SME's Corinne Cleary and Susan Cleary will be there to contribute to the innovative science behind bridging compliance and scientific advancement. 💡Feel free to chat with them about regulatory compliance in the industry and how it relates to new technologies. #innovatoin #technology #pharma #compliance #regulatorycompliance #microbiology

🚀 Breaking Boundaries: Sustainable Practices with ACQUITY QDa II Mass Detector for Drug Impurity Testing! 🌈Purity and Safety of pharmaceutical products is essential for patient health, the ACQUITY QDa II Mass Detector offers a simple, robust, and easy-to-use solution. 🧪Gain valuable insights into drug substance development and manufacturing processes to save time and money! 💚 Discover how this sustainable mass detector complements traditional LC-UV workflows: [Link to article] #DrugSafety #MassDetection #ImpurityTesting #ACQUITYQDa #QualityControl #ThePowerOfMore

What does it take to safely navigate the complex landscape of #genotoxic #impurities and how can interdisciplinary teams deal with the discovery of unexpected impurities such as #nitrosamines? That's what our experts Michael Nonnenmacher, Daniel B., Jürgen Volz and Elizabeth White will discuss in our next Fireside Chat on April 24. Have you registered yet? Genotoxic impurities are compounds that can cause damage to DNA, potentially leading to cancer and other health risks. As a #pharmaceutical company or #CDMO, it is crucial to identify and quantify these impurities to ensure that APIs, #excipients and formulations are safe and comply with #regulatory requirements. In this discussion, our industry experts draw on their experience in #toxicology, #analytics, regulatory affairs and business development to address the latest trends and challenges in genotoxic impurity testing. Curious? To learn more and save your seat for the event please visit https://lnkd.in/eU2XbrHe. #webinar #gti #m7 #api #hpapi #drugsubstance #cmo #contractmanufacturing #biopharma #pharma #healthcare #webcast Evonik

We're thrilled to announce our speakers for the 4th Annual Genotoxic Impurities Summit: Nitrosamines & Beyond! Join us as we bring together top experts in the field to dive deep into the latest advances, challenges, and regulatory updates around genotoxic impurities. 👥 This year’s speaker board includes industry pioneers, regulatory experts, and innovative thought leaders who are ready to share their invaluable insights. Don’t miss the opportunity to connect, learn, and drive meaningful change in how we approach genotoxic impurities. 📅 Mark your calendar, reserve your spot, and stay tuned for more updates on the event details! → Web Site: https://lnkd.in/gQRnEBeX → Agenda: https://lnkd.in/dvjdAMBF #Genotoxic #Nitrosamines #Pharma #Regulatory #Pharmaceutical #Innovation #NDSRI #Mutagenic #Impurities #Drug #Quality #Safety #Risk #Beyond #Analytical #Science #Toxicology #Chemical

https://lnkd.in/gYqzuUA4 Article Title: Spray dried self-nanoemulsifying drug delivery systems for sertraline HCl: Pharmacokinetic study in healthy volunteers Author(s): Hussein O. Ammar, Mahmoud M. Ghorab, Dina M. Mostafa, and Amira M. Ghoneim* Journal: International Journal of Pharmaceutical Sciences and Developmental Research Journal ISSN: 2640-7760 Abstract: Purpose: The aim of this study is to improvelow oral bioavailability of sertraline HCl by formulation and characterization ofsolid self-nanoemulsifying drug delivery system [SNEDDS] using spray drying technique. Methods: Solubility of sertraline HCl in different vehicles was determined, and ternary phase diagrams were constructed.Various formulations were prepared and characterized by morphological characterization, differential scanning calorimetry and droplet size analysis. The formulations were evaluated for In vitro release profile in comparison to the marketed product [Lustral® tablets]. The In vivo study was performed on healthy human volunteers for pharmacokinetic analysis of the optimized formulations. #SertralineHCl #Spraydrying #SelfNanoemulsifying #ReleaseBioavailability #Pharmacokinetics #Antidepressives #Pharmacy #Pharmacology #PharmaceuticalSciences #ClinicalPharmacy #MedicinalChemistry #DrugDevelopment #Pharmacokinetics #Pharmacodynamics #Pharmacogenomics #Toxicology #Pharmaceutics #Biopharmaceutics #Pharmacognosy #PharmaceuticalChemistry #PharmacyPractice #CommunityPharmacy #HospitalPharmacy #IndustrialPharmacy #RegulatoryAffairs #DrugFormulation #DrugDelivery #PharmacyManagement #PharmaceuticalTechnology #PharmacyEducation #ClinicalTrials

🧬 Webinar Alert: Dose Administration, Compatibility & Clinical Usability of Biologics 🧬 👉🏽Date: November 11, 2024 We are happy to present you a new webinar together with Pharmaceutical Technology. Get direct insights from Adithya Balasubramanian (Adi), Drug Product Expert and Business Development Director, and Hanns-Christian Mahler, CEO and #sterile product Expert, on the topic of administration of biologics and patient safety. Ensuring the quality of biological drug products (DPs) during administration is critical for patient safety. With diverse conditions across clinical sites, key considerations include proper handling, compatibility with administration containers, and ensuring product stability and sterility throughout the process. Recently, there’s been also growing attention on closed system transfer devices (CSTDs) and their potential impact on dose delivery and product compatibility. 💉 For registration and further information: https://lnkd.in/eE9qfCaK #ten23health #webinar #biologics #drugsafety #patientsafety #education #cdmo #pharma #sterile #drugadministration #Patients