Pharmacy Group Journals’ Post

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A quick and informative read. Applicable for advanced bio-sensing platforms.

Understanding the Non-Equivalency of Bio-Fluorescent Particle Counts versus the Colony Forming Unit A Special Webinar Event Presented by Modern Microbial Methods Program Overview Introduction to Bio-fluorescent particle counting technology (BFPC). Comparison between traditional CFUs and AFUs. Limitations associated with CFUs and why equivalency cannot be expected. Discussion on the consequences associated with this transition on validation of the method and/or setting new limits. Bio-fluorescent particle counting technology (BFPC), an alternative microbiological monitoring method, uses the detection of intrinsic fluorescence of microbial cells to enumerate bioburden levels in air or water samples, continuously and in “real-time”. Embracing the significant advantages of this technology requires shattering some deep-rooted paradigms in pharmaceutical microbiology, given the long history of use of traditional methods that generate results as CFUs (Colony-forming units). The basis for this is understanding the “non-equivalency” of the BFPC output signal produced, commonly referred to as an auto-fluorescent unit (AFU), which is not dependent upon growth, unlike the CFU. This expert panel hosted by METTLER TOLEDO on behalf of M3 offers a deep dive into the differences between the AFU and the CFU, discusses the limitations associated with the CFU, and why equivalency between the AFU and the CFU cannot be expected. The perspective of the Modern Microbial Methods Collaboration (M3) will be given on the consequences associated with this transition on validation of the method and/or setting new limits. This understanding will serve as a foundation to navigate challenges encountered when implementing this modern technology. For registration click on the following link: https://lnkd.in/dgqM2QtQ scott&origin=RICH_QUERY_SUGGESTION&position=0&searchId=3da3d100-ba85-4373-818a-1520d75dcd38&sid=M.X&spellCorrectionEnabled=false

Interesting report

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