Our CEO, #WouterVanPutte, will be attending the Annual #PSDI Meeting at Synchrotron #SOLEIL, Paris, November 10-12. If you're interested in learning more about #PUXANO's cutting-edge technology and services in structure-based protein design and cryoEM, feel free to connect and reach out to him directly on LinkedIn to arrange a meeting. More information on: https://lnkd.in/exjZi5VH
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From June 23-26, the 44th Annual Congress of the European Society of Mycobacteriology will be held in Bruges, Belgium. ZytoVision will be present with a booth at the conference, presenting the VisionArray MYCO Chip 2.0 (and other exciting products). The VisionArray MYCO Chip was designed to detect several different types of clinically relevant mycobacterial species. The VisionArray MYCO Chip 2.0 is used with the corresponding VisionArray MYCO PreCise MasterMix 2.0 and a VisionArray Analysis Software for a fast and reliable detection. For further information on the VisionArray system, visit our booth at the conference or our website. #zytovision #visionarray #mycobacteriology #pathogendetection
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Excited to share that our study on the cell origin of IPMN is now published! This work would not have been possible without the dedications of my postdoc, Dr. Kiyoshi Saeki, and my collaborator, Dr. Janel Kopp. In our studies, we found that Acvr1b loss, likely through abrogation of Activin signaling, is one of the few pathways identified to date that promotes precancerous lesion formation from both acinar and ductal cells expressing Kras G12D. https://lnkd.in/ei6HcgF5
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Join us for the first SACCMA Virtual Workshop Series 2024 event presented by ZEISS Microscopy!!! Come and learn more about your microscopy options when using Advanced Cell Modelling in your research. #organoid #3Dcellculture #bioimaging #spheroid #iPSC #cellmodelling
We proudly share the upcoming event hosted by SACCMA Society for Advanced Cell Culture Modelling for Africa Symposium where Chris Power and Marguerite Blignaut will be sharing their expertise in Microscopy Technologies and Advanced Cell Modelling. October 15, 2024 at 12:30 - 13:30pm Online
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We're doing a series of clips from a webinar I gave recently on the challenges in detecting biological nanoparticles--and the opportunities available if you are able to do so. First clip below, if you interest is piqued see full seminar here: https://lnkd.in/ghAwnzDi
Last month, our President and CEO, Giacomo Vacca, delivered a webinar to PATCA - Professional and Technical Consultants Association which was geared towards a better understanding of biological nanoparticles. The talk is entitled "Extremely Small and Incredibly Dim: The Quest to Find the Nanoparticles Responsible for Everything.” Dr. Vacca spoke about the foundations of flow cytometry and highlighted our Delaware Flow NanoCytometer® and its unmatched capabilities for nanoparticle analysis. This clip from the recorded talk highlights what truly matters in nanoparticle analysis, including having a device that does not clog when analyzing particles of different sizes. The Delaware provides the ease of use that is otherwise missing on the market today. We have more clips from this talk coming soon! Stay tuned, and check out the whole talk on our website: https://lnkd.in/d4M89Aj
Clog Free -- What Matters in Nanoparticle Analysis
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I am proud to present the preprint of our work “GōMartini 3: From large conformational changes in proteins to environmental bias corrections”. Take a look in the BioRxiv preprint here: https://lnkd.in/dJ9m7hSX This work started many years ago, when Sebastian Thallmair and I still shared an office as postdocs in the group of Siewert J. Marrink in Groningen. Inspired by the work of Adolfo Poma and co-workers published in 2017, the enhanced #Gō-like model combined with #Martini3 – coined #GōMartini3 - was released together with Martini 3 in 2021. After many extensive tests of community, only now we present in detail this approach and also the current Martini 3 protein model. The #GōMartini3 better captures conformation changes in proteins in relation to elastic network models, being able to capture subtle differences caused by interactions with #membranes, #smallmolecule #binding and single point #mutations. It also demonstrated capability to capture large conformational changes in #nanomechanics studies. Additionally, the model can be used to implement an environmental bias to correct recently described inaccuracies of the Martini 3 protein model, such as underestimated dimensions of #IDPs and low hydrophobicity of certain amphiphilic small #peptides. A big collaborative effort involving Sebastian Thallmair, Adolfo Poma, Siewert J. Marrink, Luís Borges Araújo, Manuel Melo, Hafez RAZMAZMA, Fabian Grunewald and many others. The Martini 3 Protein task force is only starting and many new developments should be coming this year. From my side, thanks for the support of #LBMC (Laboratory of Biology and Modeling of the Cell), #CBPsmn (Centre Blaise Pascal de Simulation et de Modélisation Numérique), #ENS de Lyon (École normale supérieure de Lyon), CNRS and CNRS Délégation Rhône Auvergne.
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In our latest publication, the result of a collaboration between Elettra Sincrotrone Trieste, Area Science Park, Università Politecnica delle Marche, and Istituto Italiano di Tecnologia, we show how infrared and plasmonic can be used to support the development of SARS-CoV-2 antivirals. Check out the full paper at the link: https://lnkd.in/dmQXnaNS #SARSCoV2 #Infrared #PandemicResearch
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I am pleased to share that I presented my recent research at The Vital Nature Sign conference today. Moreover - the publication ,,Mitochondrial Depolarization and ATP Loss During High Frequency Nanosecond and Microsecond Electroporation'' has been accepted for publication in #Bioelectrochemistry journal! 📝 I look forward to presenting the results at the forthcoming World Congress on Electroporation in #Rome! #VNS2024 #WCE2024 #InnovativeMedicineCentre #electroporation #nsPEF #mitochondria
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In our new #Big4BioPodcast episode, we spoke with Tim O'Bryan, director of discovery partnerships and commercial integration at Charles River Laboratories, and Dr. Karl Bertram, co-founder and managing director for ATEM Structural Discovery. We explore ATEM’s cryo electron microscopy technology, or Cryo-EM, its incorporation of machine learning, and how it fits in with Charles Rivers’ broader #drugdiscovery offerings. Cryo-EM enables high-resolution screening for small molecules and biological ligands, particularly for targets that are challenging to crystallize. 🎙 Listen to the episode here: https://lnkd.in/eMmTgX8s #biotech #biotechnology #machinelearning
Driving Deeper Insights into Structure-Based Drug Design with Cryo-EM by The Big4Bio Podcast
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🎙️ Tune in to the latest episode of the #Big4BioPodcast! Dive in now for expert insights! 🎧 #biotech #research
In our new #Big4BioPodcast episode, we spoke with Tim O'Bryan, director of discovery partnerships and commercial integration at Charles River Laboratories, and Dr. Karl Bertram, co-founder and managing director for ATEM Structural Discovery. We explore ATEM’s cryo electron microscopy technology, or Cryo-EM, its incorporation of machine learning, and how it fits in with Charles Rivers’ broader #drugdiscovery offerings. Cryo-EM enables high-resolution screening for small molecules and biological ligands, particularly for targets that are challenging to crystallize. 🎙 Listen to the episode here: https://lnkd.in/eMmTgX8s #biotech #biotechnology #machinelearning
Driving Deeper Insights into Structure-Based Drug Design with Cryo-EM by The Big4Bio Podcast
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🎉 We're thrilled to extend our Best Wishes to Nikon Microscope Solutions Europe for the Grand Opening of their new Nikon BioImaging Lab at the Babraham Research Campus! Today’s panel discussion on the role of microscopy in drug discovery promises to be enlightening. 🤝 At #Okolab, we’re proud to support this cutting-edge facility with our latest BL3 incubation systems. These systems feature 𝘂𝗻𝗶𝗾𝘂𝗲 𝘀𝗮𝗺𝗽𝗹𝗲 𝗳𝗲𝗲𝗱𝗯𝗮𝗰𝗸 𝘁𝗲𝗰𝗵𝗻𝗼𝗹𝗼𝗴𝘆, offering real-time control of temperature, CO2, and humidity directly at the sample level. This game-changing innovation enhances experimental reliability and effectiveness, ensuring 𝗲𝗿𝗿𝗼𝗿-𝗽𝗿𝗼𝗼𝗳 𝗼𝗽𝗲𝗿𝗮𝘁𝗶𝗼𝗻 by alerting users to setup issues before experiments begin. 💪 We’re excited to see how these advancements will empower the Nikon Instruments microscopy community! #NBIL #NikonImagingCenter #Microscopy #DrugDiscovery #Innovation #Research #LifeScience #aHistoryOfInnovation #meetBL3 #TheMicroscopeIncubationExperts #livecellimaging #NikonHealthcareUK #Nikonmicroscopy #lovecellimaging #livecells #livecellmicroscopy #automatedmicroscopy #confocal #cellbiology #cancerresearch #drugscreening #cellculture #cancerbiology #highthroughputscreening
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