SeattleNTC’s Post

SeattleNTC is participating in the prospective, multi-site Open-label Optimization (OLO) clinical research program to assess the effectiveness of the SAINT™ neuromodulation system to treat Major Depressive Disorder. Recruitment is active! Patients coming from a distance should expect to spend 2 weeks in the Seattle/Bellevue area -- the first week to get the fMRI, the second week to receive the treatment. OLO Study Summary: -         Primary objective - to assess the effectiveness of the SAINT neuromodulation system in the treatment of MDD as measured by the Clinical Global Impression Improvement Scale (GCI-I) at the end of the treatment (cessation of stimulation). -         Population - up to 1,000 adult subjects in a major depressive episode, who have failed to receive satisfactory improvement from a prior antidepressant medication in the current episode, are eligible to participate in the study if they are deemed to be appropriate candidates for transcranial magnetic stimulation (TMS). -         Study duration - expected to be approximately four years, and the study duration per subject is anticipated to be approximately one year.