Shai Fuchs M.D., Ph. D.’s Post

Postdocs, come join a team leading in chronic wasting disease research to study CWD prion strains and transmission barriers! Postdoctoral Fellow - chronic wasting disease University of Calgary See the full job description on jobRxiv: https://lnkd.in/dzf79fpm #cell_culture #crispr #mouse_models #neurodegeneration #prion_amplification_assays #prion_infection #protein_misfolding

In vitro fluidic systems: Applying shear stress on endothelial cells #Biology #FluidicSystem https://lnkd.in/gEJnHCFK Endothelial cells (ECs) that reside on the surface of blood vessels are constantly exposed to mechanical stimulation, including shear stress. Fluid shear stress (FSS) controls multiple physiological processes in ECs, regulating various pathways that maintain vascular tone and homeostasis function. The complexity of in vivo biological systems raises a demand for better in vitro techniques, which can generate FSS to closely mimic the cellular microenvironment. Through the rational design and use of flow chamber devices, in vitro fluidic systems are critical for a deeper understanding of endothelial responses to various shear conditions. The paper describes principal types of FSS systems, including functional attributes, development process and recent experiments on ECs. Finally, we prospect their possible contribution in the field of endothelial diseases. #technology #Science #research #innovation

🔬 Exciting News for Scientists! 🔬 Introducing: Nature Springer’s Borrelia burgdorferi: Methods and Protocols. Methods in Molecular Biology. Editor Leona Gilbert. https://lnkd.in/dyW8d6V6 📚 From cell and molecular biologists to statisticians and clinical researchers, these methods cater to all fields. Explore techniques for in vitro, in vivo, in situ, de novo, and clinical studies of Borrelia burgdorferi. Let's advance our understanding of infectious diseases! 💪🌍 Chapter 16 Revealed. 🌿 Dealing with Lyme Disease: A Clinical Algorithm 🌿 Lyme disease (LD) stands as the quintessential example of tick-borne infections. The array of symptoms LD presents, coupled with the wide range of sensitivity and specificity in diagnostic tests, creates a challenging landscape for diagnosis. Here, chapter 16 introduces a clinical algorithm designed for Lyme patients to help prevent delays in treatment when faced with suspicious scenarios. By navigating through this algorithm, patients can potentially streamline their journey toward accurate diagnosis and timely intervention. Let's spread awareness and empower each other in the battle against Lyme disease! 💪 #LymeDiseaseAwareness #Healthcare #Science #BorreliaBurgdorferi #ResearchMethods #InfectiousDiseases #LymeDisease #ScienceDiscoveries #TickbornePathogen #TickborneDisease #ScienceAdvances #TickBorneDiseases #InnovationInHealthcare #Tickplex @tez_ted

#MitochondrialDisease research update! 🧬 Stay informed of the latest advancements in the field with the latest papers from last week. Gavin McStay, Keshav K Singh, PhD, Biomed News World Mitochondria SocietyThe Mitochondria Research and Medicine Society The Society for Mitochondrial Research and Medicine Check out the papers here: https://lnkd.in/dywU4htW #Mitochondria #Research #Medicine Highlight: Mitochondrial double-stranded RNA homeostasis depends on cell-cycle progression

That's nearly wrap on #LabWeek! This week, we celebrated the incredible work of medical laboratory professionals, the unsung heroes of healthcare ! From analyzing blood tests to conducting complex diagnostics, they play a vital role in patient care all around the world. Let's continue to appreciate their contributions, dedication and hard work behind-the-scenes, all year round! #ThankYouLabProfessionals #HealthcareHeroes #LabLife #LabTech #MedicalLabScientist #LaboratoryTesting #Healthcare #ScienceMatters #ClinicalLaboratory #Lab #Microbiology #MolecularBiology #Pathology #Genetics #LabLove #LabProud #ScienceIsCool #MakingADifference #FutureofHealthcare

🔬 Exciting News for Scientists! 🔬 Introducing: Nature Springer’s Borrelia burgdorferi: Methods and Protocols. Methods in Molecular Biology. Editor Leona Gilbert. https://lnkd.in/gcVN_DDB 📚 From cell and molecular biologists to statisticians and clinical researchers, these methods cater to all fields. Explore techniques for in vitro, in vivo, in situ, de novo, and clinical studies of Borrelia burgdorferi. Let's advance our understanding of infectious diseases! 💪🌍 Chapter 16 Revealed. 🌿 Dealing with Lyme Disease: A Clinical Algorithm 🌿 Lyme disease (LD) stands as the quintessential example of tick-borne infections. The array of symptoms LD presents, coupled with the wide range of sensitivity and specificity in diagnostic tests, creates a challenging landscape for diagnosis. Here, chapter 16 introduces a clinical algorithm designed for Lyme patients to help prevent delays in treatment when faced with suspicious scenarios. By navigating through this algorithm, patients can potentially streamline their journey toward accurate diagnosis and timely intervention. Let's spread awareness and empower each other in the battle against Lyme disease! 💪 #LymeDiseaseAwareness #Healthcare #Science #BorreliaBurgdorferi #ResearchMethods #InfectiousDiseases #LymeDisease #ScienceDiscoveries #TickbornePathogen #TickborneDisease #ScienceAdvances #TickBorneDiseases #InnovationInHealthcare #Tickplex @tez_ted

🔬 Exciting News for Scientists! 🔬 Introducing: Nature Springer’s Borrelia burgdorferi: Methods and Protocols. Methods in Molecular Biology. Editor Leona Gilbert. https://lnkd.in/gcVN_DDB 📚 From cell and molecular biologists to statisticians and clinical researchers, these methods cater to all fields. Explore techniques for in vitro, in vivo, in situ, de novo, and clinical studies of Borrelia burgdorferi. Let's advance our understanding of infectious diseases! 💪🌍 Chapter 16 Revealed. 🌿 Dealing with Lyme Disease: A Clinical Algorithm 🌿 Lyme disease (LD) stands as the quintessential example of tick-borne infections. The array of symptoms LD presents, coupled with the wide range of sensitivity and specificity in diagnostic tests, creates a challenging landscape for diagnosis. Here, chapter 16 introduces a clinical algorithm designed for Lyme patients to help prevent delays in treatment when faced with suspicious scenarios. By navigating through this algorithm, patients can potentially streamline their journey toward accurate diagnosis and timely intervention. Let's spread awareness and empower each other in the battle against Lyme disease! 💪 #LymeDiseaseAwareness #Healthcare #Science #BorreliaBurgdorferi #ResearchMethods #InfectiousDiseases #LymeDisease #ScienceDiscoveries #TickbornePathogen #TickborneDisease #ScienceAdvances #TickBorneDiseases #InnovationInHealthcare #Tickplex @tez_ted

Thrilled to share that my PhD work is now on BioRxiv! In this study, we combined cutting-edge microfluidics, force + single-cell measurements, theoretical modeling and mouse experiments to show that bacterial growth in confined spaces generates large forces, to which bacteria adapt to in 3 steps! More info 👉 https://lnkd.in/e3M_ZSSN Excited to present this work at #SFMCongress in 2 weeks! #Microbiology #Biophysics

Happy to share our methodical paper on 3D patient-derived esophageal organoids and air liquid interface cultures (ALIs). https://lnkd.in/e9tZCk7d These two 3D cell culture models were key methods in my PhD project (https://lnkd.in/ej8gCbq8) and are fundamental for the examination of the esophageal epithelial barrier! #EoE #EpithelialBarrier #organoids #ALI

A recent pilot study assessing the efficacy of ARG-007 showed the therapeutic significantly reduced damage to brain cells in a ferret animal model of mild to moderate traumatic brain injury (modTBI), a model that closely resembles the gross anatomy of the human brain. Outlined below are the observed therapeutic effects. Learn more or read the full announcement ➡ https://lnkd.in/evuvHHN7 #ASX #AGN #TBI #traumaticbraininjury #biotechnology #lifesciences #ARG007