Simon Khagi, MD, FACP’s Post

Medical Director of Neuro-Oncology at the Hoag Family Cancer Institute

3mo

Excited to share a recent publication by my mentee and colleague, Dr. Nishika Karbhari at The Mayo Clinic describing the use of marine-derived therapeutics for #glioblastoma! Link: https://lnkd.in/gp4XuwpB Really enjoyed writing this paper. Here are some of the highlights: - Sea cucumbers, seagrass, sea urchins, and sea squirts all have bioactive compounds that have anticancer properties - Compelling activity has been shown to modulate the tumor immune microenvironment - Various antibody-drug conjugates rely on marine-derived chemotherapeutic backbones for activity - Holothurian triterpene glycosides (sea cucumbers) and fucoidans (seagrass) warrant further investigation as potential lead compounds

5 Comments

Dr. Reza Rahavi

Experimental Medicine , Faculty of Medicine, UBC, Vancouver | Medical Content Writing

2mo

Dr. Karbhari's research sounds fascinating! How did she approach her methodology? Any key findings that stood out to you? https://lnkd.in/ghrd-r3R

Erik Ortega

Site Supervisor for Medical Oncology & Specialty Clinic at Hoag Family Cancer Institute

3mo

Thank you for your research and sharing your knowledge Dr Khagi. It’s fascinating to learn that there are resources in the ocean that could benefit cancer patients.

Neal K. Shah

America's Chief Elder Officer | CEO at CareYaya Health Technologies | Co-Founder of Counterforce Health | CY Multiscale AI

3mo

Fascinating!

Daniel Pomeranz Krummel, PhD

Chapel Hill NC based academic researcher with interest in primary and metastatic brain cancers; CEO of startup

3mo

Fascinating👍

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