Temasek Life Sciences Accelerator’s Post

🚀 A Breakthrough in Reproductive Health? 🚀 Exciting new research: early results from the Vibrant (Validating Benefits of Rapamycin for Reproductive Aging Treatment) study suggest that the drug rapamycin could extend women’s fertility by up to five years and potentially improve overall health and longevity. This research, led by Professor Yousin Suh and Dr. Zev Williams at Columbia University, marks a significant shift in how we approach menopause and ovarian ageing. 🧬 Key Findings: - Rapamycin, an immunosuppressant, might slow ovarian ageing, delay menopause, and reduce age-related disease risks. - Early results show a 20% reduction in ovary ageing with minimal side effects. - Participants have reported improvements in health, memory, energy levels, and skin and hair quality. While these findings are promising, they also raise important questions: 🔍 Are We Medicalising Women’s Health? Is delaying menopause truly beneficial, or are we overlooking the value of embracing natural life stages? Many women find they love their post-menopausal years. 🤔 What About Long-Term Implications? The study is still in its early stages. We need to explore whether the benefits of extending fertility outweigh potential risks and whether this intervention addresses the root causes of age-related health issues. 💬 What do people think? Is extending fertility and delaying menopause a game-changer for women’s health, or should we focus on enhancing the quality of life during all stages of ageing? https://lnkd.in/dGWa846v #Rapamycin #MenopauseResearch #Fertility #WomenHealth #MedicalInnovation #Aging #HealthResearch

Understanding the Critical Role of AMH in Women's Health 🌺 🤱 Did you know? In females, AMH (Anti-Müllerian Hormone) is produced by developing follicles. At birth, women have between 0.5 and 1 million oocytes in the form of primordial follicles. By age 50, this number drops to almost zero, with only 0.1% of these follicles developing into a fertilisable egg. As follicles develop into antral follicles, they can be measured by transvaginal ultrasonography to estimate ovarian reserve. However, this method can be subjective and dependent on the sonographer's expertise. AMH closely correlates with antral follicle count and offers a more objective measure without requiring specialized equipment or highly trained staff, which has led to its increased use in recent years. 🔬 Applications of AMH: ✔ IVF: High AMH levels are linked to the intensity of ovarian response, oocyte yield, and live birth rates. It plays a crucial role in guiding ovarian stimulation medication to avoid ovarian hyperstimulation. ✔ PCOS: High AMH levels in women with Polycystic Ovary Syndrome (PCOS) have been associated with a lower chance of responding to treatments like laparoscopic ovarian drilling. ✔ Ongoing Research: The implementation of AMH as a biomarker is growing rapidly, with further research exploring its potential uses, such as in predicting menopause. As the understanding and use of AMH continue to evolve, it remains a powerful tool in women's health, offering valuable insights into fertility and reproductive health. #WomensHealth #AMH #Fertility #IVF #PCOS #HealthcareInnovation #LepziLtd #ReproductiveHealth #OvarianReserve #Menopause #MedicalResearch #Biomarkers #HealthcareTechnology #ClinicalDiagnostics #Gynecology #WomensHealthCare #AMHTesting #OvarianHealth #InnovationInHealthcare #IVFSuccess #FertilityAwareness #PCOSTreatment For more information, visit our website 🌍 www.lepzi.com or contact us at 📧 enquiries@lepzi.com.

**"🌟 The Future of Steroid Science Awaits You! 🌟"** 🔊 Join us at the Global Congress on Steroids, Aug 18-19, 2025, in Lisbon, Portugal. Connect with leading experts to explore cutting-edge research and innovations in steroid applications. 🌍 📅 Save the date: August 18-19, 2025. 📍 Venue: Lisbon, Portugal. https://lnkd.in/gFCxinrf 🌟 Steroids in Reproductive Health and Development: A Transformative Role "Steroids play a crucial role in reproductive health, influencing hormonal balance, fertility, and developmental processes. They are key in understanding and addressing conditions like hormonal disorders, infertility, and developmental abnormalities." Join the discussion at the Global Congress on Steroids to explore: ✅ Steroids in treating infertility and hormonal imbalances. ✅ Innovations in reproductive therapies and growth-related research. ✅ Long-term impacts of steroid use in reproductive health. ✅ Cutting-edge fertility treatments involving steroids. ✅ Hormonal therapies for reproductive and developmental health. ✅ Research on steroids’ role in life-stage transitions. #ReproductiveHealth #SteroidsResearch #HormonalBalance #DevelopmentalScience #MedicalInnovation #FertilityResearch #InfertilitySolutions

March marks Endometriosis Awareness Month—a time dedicated to shedding light on a condition that affects millions of individuals worldwide. Endometriosis is a chronic and often debilitating reproductive health disorder where tissue similar to the lining of the uterus grows outside the uterus. Despite its prevalence, endometriosis remains widely misunderstood, underscoring the importance of education and awareness. Why is it crucial that we educate people about endometriosis? Firstly, because awareness leads to early diagnosis and intervention. Far too many individuals suffer in silence for years before receiving a proper diagnosis, enduring excruciating pain and debilitating symptoms. By raising awareness, we empower individuals to recognise the signs and symptoms of endometriosis and seek medical help sooner. Furthermore, education is essential for dispelling myths and misconceptions surrounding endometriosis. It’s not just “bad periods” or “normal menstrual cramps.” Endometriosis can significantly impact quality of life, affecting everything from fertility and relationships to mental health and daily activities. So, how can we help? As allies and advocates, there are several ways we can support those affected by endometriosis: Create safe spaces for individuals to share their experiences without judgment. Validate their pain and struggles, and offer empathy and support. Use your platform to raise awareness about endometriosis. Share informative resources, personal stories, and educational content to help dispel stigma and increase understanding. Advocate for improved healthcare practices and policies surrounding endometriosis. Encourage healthcare providers to receive training in recognising and treating endometriosis effectively. Support organisations and initiatives dedicated to researching endometriosis, developing better treatments, and ultimately finding a cure. Fortunately, there are organisations and resources available to provide support and assistance to individuals living with endometriosis: • The Endometriosis Foundation of America : Dedicated to increasing disease recognition, providing advocacy, and fostering scientific research. • The Endometriosis Association Committed to providing education, support, and research funding for individuals affected by endometriosis. • Endometriosis UK: Offers support services, information, and resources for individuals in the UK living with endometriosis. By coming together as a community, we can help raise awareness, improve support systems, and ultimately improve the quality of life for individuals living with endometriosis. Let’s stand in solidarity with those affected and work towards a future where endometriosis is widely understood, effectively treated, and where all individuals receive the support and care they deserve. #EndometriosisAwarenessMonth #Endometriosis #Awareness #Support #Education #Advocacy #Empathy #Healthcare #Community #Solidarity

Title: Unveiling the Nexus Between Oral Health and Infertility: Key Insights 🦷👶 1. **Gum Disease and Reproductive Health**: Studies by researchers like Dr. Roger Hart from the University of Western Australia have highlighted the correlation between gum disease and fertility issues. Chronic inflammation from gum disease may disrupt reproductive processes. 2. **Impact of Dental Treatments**: Research, including studies by Dr. Mahmoud Goudarzi from Tehran University of Medical Sciences, suggests that certain dental procedures, such as root canals and extractions, might affect fertility. Understanding these implications is crucial for reproductive health. 3. **Systemic Inflammation**: Poor oral health can contribute to systemic inflammation, potentially affecting fertility. Researchers like Dr. Susan G. Kornstein from Virginia Commonwealth University emphasize the importance of addressing oral health as part of overall wellness, especially for individuals planning to conceive. 4. **Hormonal Imbalance**: Dental issues may contribute to hormonal imbalances, impacting fertility. Research by Dr. Mariano Sanz from Complutense University of Madrid underscores the need for further exploration into the intricate relationship between oral health and reproductive function. 5. **Sperm Count and Quality**: Oral health may influence sperm count and quality. Studies by Dr. Ashok Agarwal from Cleveland Clinic have suggested a potential link between periodontal disease and reduced sperm count. This highlights the importance of oral hygiene in optimizing male reproductive health. 6. **Preventive Measures and Awareness**: Regular dental check-ups, effective oral hygiene practices, and timely treatment of dental problems are essential preventive measures. Raising awareness about the link between oral health and fertility empowers individuals to prioritize their reproductive well-being. By integrating oral health into fertility discussions and practices, individuals can enhance their chances of conceiving and maintaining a healthy pregnancy. Let's continue exploring this intersection to optimize reproductive health. #OralHealth #FertilityResearch #WellnessAwareness #Giridihdentist #India🌱✨

💡 Understanding the Importance of FSH Testing in Women's Health Follicle-Stimulating Hormone (FSH) plays a crucial role in women's reproductive health and fertility. Testing FSH levels provides essential insights that can guide healthcare decisions and improve patient outcomes. At Lepzi Ltd., we recognize the critical role of accurate and timely diagnostics, which is why we offer a point-of-care FSH test that delivers quantitative results in less than 15 minutes using urine samples. 🩺 Why Test FSH Levels? ✔Fertility Assessment: FSH levels help evaluate ovarian reserve, which is critical for understanding a woman's fertility potential. High FSH levels may indicate a reduced number of viable eggs. ✔Menstrual Cycle Regulation: FSH is key in regulating the menstrual cycle. Testing can help diagnose conditions like Polycystic Ovary Syndrome (PCOS) and other menstrual irregularities. ✔ Menopause and Perimenopause: Elevated FSH levels can signal the transition into menopause, aiding in the management of symptoms and overall health during this stage. ✔Diagnosing Reproductive Disorders: Abnormal FSH levels can indicate reproductive issues such as ovarian failure or hypogonadism, guiding further diagnostic and treatment plans. 🔬 Benefits of FSH Testing: ✔Timely Interventions: Quick and accurate results enable timely medical interventions, crucial for managing reproductive health. ✔Personalised Care: FSH testing supports personalised treatment plans in assisted reproductive technologies (ART) like IVF, improving the chances of success. ✔Comprehensive Health Management: Monitoring FSH levels provides a comprehensive view of a woman's reproductive health, aiding in early detection and management of various conditions. Our Lepzi FSH test is designed to support healthcare practitioners in delivering efficient and personalized care, enhancing patient outcomes. 🌍 Join us in advancing women's health diagnostics with innovative technology! hashtag #FSH hashtag #Urine_Quantitative_Test hashtag #PointOfCareTesting hashtag #WomensHealth hashtag #HealthcareInnovation hashtag #MedicalDiagnostics hashtag #LepziLtd For more information, visit our website 🌍 www.lepzi.com or contact us at 📧 enquiries@lepzi.com

March marks Endometriosis Awareness Month—a time dedicated to shedding light on a condition that affects millions of individuals worldwide. Endometriosis is a chronic and often debilitating reproductive health disorder where tissue similar to the lining of the uterus grows outside the uterus. Despite its prevalence, endometriosis remains widely misunderstood, underscoring the importance of education and awareness. Why is it crucial that we educate people about endometriosis? Firstly, because awareness leads to early diagnosis and intervention. Far too many individuals suffer in silence for years before receiving a proper diagnosis, enduring excruciating pain and debilitating symptoms. By raising awareness, we empower individuals to recognise the signs and symptoms of endometriosis and seek medical help sooner. Furthermore, education is essential for dispelling myths and misconceptions surrounding endometriosis. It’s not just “bad periods” or “normal menstrual cramps.” Endometriosis can significantly impact quality of life, affecting everything from fertility and relationships to mental health and daily activities. So, how can we help? As allies and advocates, there are several ways we can support those affected by endometriosis: Create safe spaces for individuals to share their experiences without judgment. Validate their pain and struggles, and offer empathy and support. Use your platform to raise awareness about endometriosis. Share informative resources, personal stories, and educational content to help dispel stigma and increase understanding. Advocate for improved healthcare practices and policies surrounding endometriosis. Encourage healthcare providers to receive training in recognising and treating endometriosis effectively. Support organisations and initiatives dedicated to researching endometriosis, developing better treatments, and ultimately finding a cure. Fortunately, there are organisations and resources available to provide support and assistance to individuals living with endometriosis: • The Endometriosis Foundation of America : Dedicated to increasing disease recognition, providing advocacy, and fostering scientific research. • The Endometriosis Association Committed to providing education, support, and research funding for individuals affected by endometriosis. • Endometriosis UK: Offers support services, information, and resources for individuals in the UK living with endometriosis. By coming together as a community, we can help raise awareness, improve support systems, and ultimately improve the quality of life for individuals living with endometriosis. Let’s stand in solidarity with those affected and work towards a future where endometriosis is widely understood, effectively treated, and where all individuals receive the support and care they deserve. #EndometriosisAwarenessMonth #Endometriosis #Awareness #Support #Education #Advocacy #Empathy #Healthcare #Community #Solidarity

📢 Did you know that  infertility is an under-recognized risk factor for Intimate Partner Violence (IPV) against women? #NοExcuse On this International Day for the Elimination of Violence Against Women United Nations, and as we begin the 16 Days of Activism against Gender-Based Violence, we at NESTOR- Innovation in Reproductive Healthcare want to bring attention to this critical yet often overlooked issue.   For  women, the emotional and physical burden of infertility is compounded by societal stigma and, tragically, by abusive behaviors from partners or families.   In their published comprehensive systematic literature review in Lancet Global Health (2023) authors call for more population based studies and highlight the need for structural interventions at the socio-ecological level. 🔗 https://lnkd.in/dpzKtxRC   At NESTOR- Innovation in Reproductive Healthcare, we believe that addressing infertility must go beyond medical solutions.  By shining a light on the intersection of infertility and gender-based violence, we hope to inspire action and create meaningful change.   As we observe this day and engage in the 16-day campaign, we invite everyone—healthcare providers, policymakers, and advocates—to join us in building a future where women are free from violence and empowered in their reproductive choices. European Society of Human Reproduction and Embryology (ESHRE) European Research Executive Agency (REA) Fertility Europe #OrangeTheWorld #EndViolenceAgainstWomen #InfertilityAwareness #GenderEquality #ReproductiveHealth #EuropeanResearchExecutiveAgency #HorizonEU    

A common drug, rapamycin, is showing promising potential for extending female fertility, delaying menopause, and improving overall health and longevity in women. Originally developed as an immunosuppressant for organ transplant patients, rapamycin has recently garnered attention in the field of antiaging medicine due to its unique effects at different dosages. Dr. Zev Williams, Director of Columbia University Fertility Center, explained to *Newsweek* that while rapamycin at high doses is used to suppress the immune system to prevent organ rejection, at lower doses, it can actually enhance the immune system and slow the aging process across various animal models. This antiaging effect is believed to be linked to rapamycin’s ability to activate autophagy, a cellular process that recycles and removes accumulated cellular debris, which typically builds up with age. By promoting autophagy, rapamycin may help slow down or even reverse some aspects of the aging process. One particularly exciting area of research focuses on rapamycin's impact on the ovaries, which play a crucial role in female fertility. The ovaries age faster than most other organs, and the decline in their function leads to reduced fertility and menopause. By potentially delaying these processes, rapamycin could extend the reproductive lifespan of women and delay menopause, offering significant benefits for women's health and longevity. While more research is needed, the implications of these findings are profound, suggesting that rapamycin could be a key player in the future of antiaging therapies, especially concerning female reproductive health.

Learn about the crucial role of FSH in women's health and how our rapid, quantitative urine test can make a difference. For more info, contact me at 📧 marinova@lepzi.com or 📞 +359878141112. #FSH #POCT #WomensHealth #MedicalDiagnostics #LepziLtd