The Antibody Society’s Post

IOS-1002 is a multi-functional agent based on a naturally occurring human leukocyte antigen that targets multiple immune checkpoints ( LILRB1 (ILT2), LILRB2 (ILT4) and KIR3DL1) to activate both innate and adaptive immune cells. IOS-1002 (formerly iosH2) is described as an open format (peptide free conformation) and expression- and stability-optimized HLA-B57-B2m-IgG4_Fc fusion protein.

View profile for Osiris Marroquin Belaunzaran, graphic

Biotech Executive | Entrepreneur

I’m thrilled to share the publication of my latest article alongside the brilliant team at ImmunOs Therapeutics AG!. Our article explores the novel use of HLA molecules as cancer therapeutics, providing insights on the development and pre-clincal work of IOS-1002. It’s been an honor to lead this project alongside such a dedicated group of professionals. This piece of research represents not only years of hard work, but it also represents a significant milestone in the journey of bringing novel concepts of immunotherapy from bench to bedside.  IOS-1002 is currently tested in Phase I clinical trials for diverse cancer indications. I invite you to read our article and share your insights. https://lnkd.in/eVfXAcZ2 #Innovation #Research #Immunotherapy #benchtobedside #Biotech

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