The Quantum Insider’s Post

Collaboration with domain experts is essential to unlock high-impact quantum applications. Our latest blog, "Co-Design of Hybrid Quantum-Classical Applications in Multimodal Cancer Research," in ACM SIGARCH, highlights the collaboration between our quantum experts and domain specialists to discover biomarkers in cancer data for Wellcome Leap’s Q4Bio program. Key Takeaways: 1️⃣ Hybrid Solutions: Real applications will combine quantum and classical computation, co-designed to leverage each's strengths. 2️⃣ Domain Collaboration: Working with experts in fields like cancer research is essential for identifying computational tasks that benefit from quantum speedup. 3️⃣ Broader Implications: While we showcase cancer research, our approach extends to other domains, such as PNT, logistics, and materials science. Read more to explore how Infleqtion is pushing the boundaries of what's possible with quantum computing: https://lnkd.in/g739pC8k #QuantumComputing #CancerResearch #Innovation #Technology #HybridComputing #Infleqtion

🚀 Accelerating Genomic Analysis with Cutting-Edge Technology. The Sanger Institute has made a groundbreaking advancement in genomic analysis by leveraging the Burrows-Wheeler Aligner (BWA) with their proprietary CaVEMan workflow on CPUs, and now tapping into Parabricks on NVIDIA GPUs. 🔍 **Impressive Results: - Energy Efficiency: Up to 42X less energy consumption - Cost Savings: 24X less expensive - Runtime Reduction: 1.6X faster By utilizing a single NVIDIA DGX system instead of 128 dual-socket CPU servers, the institute annually consumes about 125 million CPU hours for sequencing 10,000 genomes. This switch could save the Sanger Institute approximately $1 million and 1,000 megawatt-hours each year—equivalent to powering an average American home for a century! 🏠💡 This innovation not only enhances efficiency but also significantly reduces environmental impact, marking a major step forward in sustainable genomic research. 🌍🔬 #Genomics #Innovation #Sustainability #NVIDIA #Parabricks #BWA #SangerInstitute

Photodynamic therapy is an emerging procedure for noninvasive cancer treatment in which the drug (BODIPY photosensitizer) upon light activation transfers energy or electrons to the surrounding environment that cause cellular death. Quantum chemistry simulations offer a cost-effective way for computational design of BODIPY photosensitizers with potential use in photodynamic therapy. Unfortunately, accurate predictions of excitation energies pose a challenge for the popular methods and reliable descriptions can be achieved by expensive multi-reference quantum chemistry methods. Alternatively, quantum computing holds a potential for exact simulation of photophysical properties of BODIPY photosensitizers in a computationally more efficient way. Our researchers, in collaboration with Vijay Krishna from Cleveland Clinic, introduce the state-specific ∆ADAPT-VQE method suitable for quantum devices in which the electronically excited state is calculated via a non-Aufbau configuration. We show that the proposed method predicts accurate excitation energies that are not only in good agreement with experiments but also outperform other popular quantum chemistry methods. This work is supported by Wellcome Leap as part of the Q4Bio Program and marks a successful start of collaboration between Algorithmiq and Cleveland Clinic. Congrats to the authors Anton Nykänen, Leander Thiessen, Elsi-Mari Borrelli, Vijay Krishna, Stefan Knecht, Fabijan Pavosevic Read the full article here 👉 https://lnkd.in/diKteqZT

Philo - Prin - Nat - Phen The blood-brain barrier (BBB) is a highly selective semipermeable membrane that separates the circulating blood from the brain extracellular fluid in the central nervous system (CNS). It plays a crucial role in protecting the brain from harmful substances while allowing essential nutrients and molecules to pass through. Key features of the blood-brain barrier include: 1. Tight junctions: Specialized cells called endothelial cells line the capillaries in the brain and are connected by tight junctions. These junctions form a physical barrier that restricts the passage of large molecules, pathogens, and toxins from the bloodstream into the brain. 2. Astrocytes: Astrocytes are star-shaped cells that surround blood vessels in the brain. They contribute to the integrity of the BBB by releasing chemical signals that regulate the permeability of the endothelial cells. 3. Pericytes: Pericytes are contractile cells that wrap around capillaries and venules in the brain. They play a role in maintaining the structural integrity of blood vessels and regulating blood flow to the brain. 4. Efflux transporters: Specialized proteins called efflux transporters actively pump certain substances out of brain endothelial cells back into the bloodstream, further restricting the passage of potentially harmful molecules into the brain. While the blood-brain barrier is essential for protecting the brain, it can also pose challenges for the delivery of therapeutic drugs to treat neurological disorders. Researchers are exploring various strategies to bypass or modulate the BBB to improve drug delivery to the brain, including the development of nanoparticle-based delivery systems and the use of focused ultrasound to temporarily open the barrier. Understanding the blood-brain barrier is crucial for developing effective treatments for brain diseases and disorders.

🌟 Excited to Announce My Latest Publication! 🌟 I’m thrilled to share that our paper, "A cyclical fast iterative method for simulating reentries in cardiac electrophysiology using an eikonal-based model", has just been published in Engineering with Computers! 📝 In this work, we introduce the newest version of the Diffusion Reaction Eikonal Alternant Model (DREAM), a computational model for simulating cardiac arrhythmias. By integrating the eikonal model with conduction velocity restitution and alternating it with an approximated reaction–diffusion model, DREAM contributes to ongoing efforts in cardiac electrophysiology research. Key highlights include: ⚡ DREAM enables reentry simulations at coarse resolutions, significantly increasing computational speed compared to traditional reaction–diffusion models. 🔄  Introducing the cyclical fast iterative method, which solves the eikonal equation to model reactivations and reentries in anisotropic media. 📈 A publicly available implementation in the openCARP simulator, making it accessible for the broader research community. This achievement wouldn’t have been possible without the incredible contributions of my co-authors: Jorge Sánchez Arciniegas, Stephanie Appel, Silvia Becker, Jonathan Krauß, Patricia Martínez, Laura Anna Unger, Marie Houillon & Axel Loewe and the support of all the other members of the CaMo KIT who contributed in some way to this work 🙏 📖 Read the full paper here: https://lnkd.in/er5qqipA Your insights or ideas for collaboration on this topic would be most welcome! #CardiacElectrophysiology #ScientificPublication #EngineeringWithComputers #openCARP

Half light, half matter: new quantum particles The prospects for the development of computing and communications technologies based on the quantum properties of light and matter may have taken a big step forward, thanks to research by physicists at the City College of New York led by Vinod Menon. In pioneering work, Professor Menon and his team were able to detect half-light, half-matter particles in atomically thin semiconductors \(one-millionth of a sheet of paper thick\) consisting of a two-dimensional layer of molybdenum and sulfur atoms arranged in a similar arrangement to graphene. They squeezed this two-dimensional material into the light that entered the structure and revealed the constituent quantum particles. Besides being fundamental, this breakthrough opens up the possibility of creating devices that take advantage of both light and matter, Menon says. For example, he is referring to the creation of logic bridges and signal processors that take the best of light and matter. The discovery will also contribute to the development of practical platforms for quantum computing. Dirk Englund, an MIT professor whose research focuses on quantum technologies based on semiconductors and optical systems, welcomes the City College study. What's interesting and exciting about Vinod and his team's work is how easily this powerful communication mode can be achieved. They convincingly showed that by combining a fairly standard dielectric cavity with exciton-polaritons in a monolayer of molybdenum disulfide, one can obtain a strong coupling mode with a very powerful pulling force." The work was published in Nature Photonics. If you've read the article this far please like and subscribe - it really helps the channel. Open the link to find thousands of interesting articles: https://lnkd.in/dNyiufB5 \#nikolays_genetics_lessons

This is a great opportunity for those who want to step into quantum computing: Quantum Computing: New Frontiers in Biomedical Research (https://lnkd.in/ePDt6zXe)

A major new research hub led by the University of Cambridge and UCL aims to harness quantum technology to improve early diagnosis and treatment of disease. The hub, called Q-BIOMED, is one of five quantum research hubs announced on 26 July by Peter Kyle MP, the Secretary of State for Science, Innovation and Technology, supported by £160 million in funding. The hub will exploit advances in quantum sensors capable of detecting cells and molecules, potentially orders of magnitude more sensitively than traditional diagnostic tests. This includes developing quantum-enhanced blood tests to diagnose infectious diseases and #cancer quickly and cheaply using portable instruments, and #sensors measuring tiny changes to the magnetic fields in the brain that have the potential to detect early markers of #Alzheimer’s disease before symptoms occur. Richard Penty Chander Velu Adrian Wonfor https://lnkd.in/eBXEANqP

#cancer #neurologicaldiseases #diabetic Ai Quantum computing in the fight against cancer and Co: Lilly can be anyone and anything." In quantum computing, Lilly embodies the concept of superposition, allowing her to exist in multiple states simultaneously, representing anything and anyone at once. Quantum computing indeed has fascinating properties that allow particles to exist in multiple states simultaneously, a concept known as superposition. While "Lilly" being "anything and anyone" is a creative interpretation, in a more technical sense, it could be likened to a qubit being in a superposition of multiple states. This allows quantum computers to perform complex calculations much faster than classical computers. Is this the technology for curing cancer and other diseases?

AI Brains: FinalSpark's Biocomputers Pave the Way for a Sustainable Future Swiss tech firm FinalSpark has unveiled Neuroplatform, a revolutionary biocomputing platform that uses human brain cells—organically grown organoids—as computing units. This innovative approach marks a significant step towards creating AI systems that are much more energy-efficient than traditional silicon-based models. By connecting clusters of brain organoids to electrodes and training them with dopamine, Neuroplatform mimics the learning processes of human brains, potentially enabling these biocomputers to perform tasks akin to modern CPUs and GPUs. Stay ahead with the latest insights and breakthroughs in AI-driven healthcare. Subscribe now for free to read our upcoming newsletter- https://lnkd.in/drMdAFND #hearthealth #aihealthcare #healthcare #ainews #aiinmedicine #heartdisease #aibreakthroughs #aiinnovation #aidevelopments #cancercare #cancer #diabetes #breastcancer #biocomputers #biotechnology