Mike Hines PhD’s Post

Primary Physicians and Pelvic Providers: Include a digital therapeutic in your treatment plan for patients with persistent pelvic pain. Many patients are challenged to find, afford or are on long wait lists for non-pharmacological therapy providers. To prevent further pain catastrophizing, depression, anxiety and pain, teach patients the value of learning pain science education and self care by using an online home program concurrently with medical care. Digital therapeutics are affordable, evidence-based software programs providing immediate access to guide patients in the knowledge and skills to lower pain and potentially improve your patient outcome. PelvicSense is a digital therapeutic for women with persistent pelvic pain. Currently in research measuring efficacy for women diagnosed with Vulvodynia, Endometriosis and PGAD. Results by Q1 2025. Article #1: Developing Digital Therapeutics for Chronic Pain in Primary Care: A Qualitative Human-Centered Design Study of Providers’ Motivations and Challenges https://lnkd.in/eVwtAmaG Article #2: Digital health in pain assessment, diagnosis, and management: Overview and perspectives. https://lnkd.in/eUETkppz

Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial Study Title: Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial Summary This study compared the effectiveness of different treatments for knee osteoarthritis (KOA). It involved 60 patients aged 48-80 with grade 2 or 3 KOA. Patients were divided into three groups and received different treatments. The study measured pain, joint function, and pressure pain threshold at 2, 4, and 8 weeks. Results After treatment, all groups showed improvement in pain, joint function, and pressure pain threshold. At 4 and 8 weeks, the combined treatment group showed significantly lower pain and better joint function compared to the other groups. The pressure pain threshold also improved significantly in the combined treatment group compared to the single treatment groups. Conclusion The study suggests that the combined treatment of intra-articular prolotherapy and peri-articular perineural injection is more effective in reducing pain and improving knee function in the short term. This combination could be considered by clinicians to improve symptoms in KOA patients. Clinical Trials and AI in Healthcare Clinical trials are crucial for developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates clinical standards and research for clinicians. Additionally, our mobile apps support scheduling, monitoring treatments, and telemedicine, streamlining operations and expanding digital services to improve patient care and outcomes. By using AI, clinics can enhance workflows and reduce paper routines. Learn more about how we can help at aidevmd.com. https://lnkd.in/gUY-RSKU #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics

Effectiveness of diagnosis and treatment based on movement system impairment in individuals with cervical pain: A randomized controlled trial Effectiveness of Movement System Impairment Model in Treating Neck Pain: Clinical Trial Results Background Movement System Impairment (MSI) classification and treatment effectively diagnose and treat individuals with neck pain. Current guidelines lack movement-specific mechanical diagnosis for neck pain management. Purpose This study aimed to investigate the effectiveness of the movement system impairment model among neck pain individuals. Methods The study was a randomized controlled trial with 82 participants screened, and 60 individuals meeting the criteria were randomized into experimental and control groups. Both groups received treatment and were assessed for pain intensity, cervical range of motion, muscle strength, endurance, and disability. Results After 10 treatment sessions over three weeks, both groups showed significant improvements in pain intensity, range of motion, muscle strength, endurance, and disability. The experimental group (MSI) demonstrated greater clinical benefits than the control group. Conclusion The movement system impairment model effectively diagnosed and treated neck pain in individuals with mobility deficits. Further research is needed to establish its long-term effects. Value in Clinical Practice Clinical trials are crucial for developing safe treatments. Our AI-driven platform, DocSym, consolidates standards, protocols, and research into an easily accessible knowledge base. Streamlining operations is essential in today’s healthcare environment, and our mobile apps support scheduling, monitoring treatments, and telemedicine to enhance workflows and improve patient outcomes. Learn more at aidevmd.com. https://lnkd.in/gc52CDDQ #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics

Evaluation and randomised controlled trial of home urinalysis testing in patients with SLE at elevated risk for developing lupus nephritis: a study protocol Evaluation of Home Urinalysis Testing in Patients with SLE Study Overview This study focuses on lupus nephritis (LN), a common issue for patients with systemic lupus erythematosus (SLE). Up to 60% of adult SLE patients may develop LN, which can lead to serious kidney problems. Minority groups often face worse outcomes, making early detection crucial. Practical Solutions We are testing a home urine sampling method combined with text message reminders to help patients at high risk for LN. The study will have two phases: Phase 1: A pilot trial with 18 participants to assess feasibility and gather feedback. Phase 2: A larger trial with 160 participants to compare the effectiveness of home testing against standard care. Value of the Study The goal is to see if weekly home urine tests can detect kidney issues earlier than traditional methods. Early detection could lead to better treatment and improved health outcomes. Future Implications The results will help shape future home testing methods and improve patient care through timely interventions. Registration This trial will be registered on ClinicalTrials.gov before participant enrollment begins. Enhancing Clinical Trials with Technology Clinical trials are essential for developing effective treatments. Our AI-driven platform, DocSym, integrates clinical guidelines and research into one easy-to-use resource for healthcare providers. Streamlining Healthcare Our mobile applications facilitate scheduling, treatment monitoring, and telemedicine, making patient care more efficient and accessible. Improving Outcomes By leveraging AI, clinics can optimize their processes, enhance patient care, and reduce reliance on paper. Discover more at aidevmd.com. https://lnkd.in/gbx2iAeq #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics

How do Physicians consider and ultimately prescribe a therapy for a patient diagnosed with Multiple Sclerosis? There are many market research/syndicated studies that aid in understanding the performance of a particular therapy in a disease area - RxY stands out as the only syndicated study to support the true why / why not - behind physician treatment choices for dynamic patients.  At RxY, we purposefully design our patient chart audit in order to bridge the qualitative-quantitative gap and address this question. The RxY Multiple Sclerosis patient chart audit includes: • Focusing on Dynamic Patients - initiations and switches. Understanding the true why/why not for-why a physician considers and prescribes a therapy. This allows our clients to win greater patient shares, by making data driven decisions that optimize marketing strategies. • Collection and analysis of the following number of Dynamic Patient charts within the Multiple Sclerosis therapeutic area: o USA - 7,937 since 2020 o EU5 - 5,944 since 2021 o Japan - 715 in 2023 o Brazil - 270 in 2023 • Treatment decision verbatims collected from physicians on the true why / why not o USA - 39,685 o EU - 29,720 o Japan - 3,575 o Brazil - 1,350 • Delivery of rich qualitative data with the confidence of robust quantitative samples If you would like to learn more about our work at RxY and see the complete list of Therapy Areas we cover, visit our website - https://lnkd.in/dsP-cHqU Please feel free to contact me directly if you have any questions molly.feda@rxyhc.com

We're excited to share our latest publication, "Lightening the Load: Generative AI to Mitigate the Burden of the New Era of Obesity Medical Therapy." 🌐 This paper explores how AI-powered solutions can streamline the management of GLP-1/dual receptor agonist medications, easing the strain on healthcare systems while improving patient outcomes. A must-read for healthcare professionals, AI enthusiasts, and policymakers aiming to shape the future of medical care. 📘 Access the full text here: https://lnkd.in/esAB3x4T #AIinHealthcare #ObesityTherapy #HealthTechInnovation

Recursion Advances AI-Based C. Diff Candidate to Phase II https://lnkd.in/gBkE_S8z REC-3964 is designed to treat C. diff by selectively inhibiting the glucosyltransferase activity of toxin B produced by the bacterium in the gastrointestinal tract, offering a different mechanism of action from antibiotics. The post Recursion [...]

Acute severe pain in emergency department: Morphine or low-dose ketamine? Acute Severe Pain in Emergency Department: Morphine vs. Low-Dose Ketamine Introduction Severe pain is a critical issue that can be dangerous due to its location and potential misdiagnosis. Aim This study aimed to compare the effectiveness of morphine and low-dose ketamine for treating severe pain in the emergency department. Methods We conducted a randomized open study with patients over 18 years old experiencing severe pain (NRS ≥6). The morphine group received 10 mg of morphine, while the low-dose ketamine group received 30 mg of ketamine. We measured the effectiveness by checking if patients achieved an NRS of less than 4 within 10 minutes. Results We included 120 patients: 66 in the morphine group and 54 in the low-dose ketamine group. The average pain score at the start was similar for both groups (8.8 for morphine and 8.6 for ketamine). After 10 minutes, both groups had a similar number of patients reaching an NRS of less than 4. However, the average pain score was significantly lower in the low-dose ketamine group. More side effects were reported in the low-dose ketamine group. Conclusions Low-dose ketamine is as effective as morphine for managing severe pain in the emergency department. Clinical Trial Importance Clinical trials are essential for developing safe and effective treatments. It’s vital to integrate their findings into everyday medical practice. Practical Solutions DocSym, our AI-driven platform, consolidates ICD-11 standards, clinical protocols, and research into an easy-to-use resource for healthcare providers. Value of Streamlining Operations In today’s healthcare landscape, efficiency is key. Our mobile apps assist with scheduling, treatment monitoring, and telemedicine, simplifying patient care management. Enhancing Workflows with AI By leveraging AI, clinics can improve workflows, enhance patient outcomes, and reduce paperwork. Discover how we can assist you at aidevmd.com. https://lnkd.in/gKe4JZ5j #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics

COMPARISON OF EFFICACY OF NSAIDS WITH INTRA- ARTICULAR INJECTION OF CORTICOSTEROIDS IN PATIENTS OF TEMPOROMANDIBULAR DISORDER WITH INTERNAL DISC DISPLACEMENT WITHOUT REDUCTION Comparison of NSAIDs and Corticosteroids for Temporomandibular Disorder Study Overview This study investigates the effectiveness of NSAIDs versus corticosteroid injections for treating Temporomandibular Disorder (TMD) caused by disc displacement without reduction. TMD can affect the joint and surrounding muscles, and its prevalence varies widely. The trial was conducted at Faisalabad Medical University in Pakistan over one year. Methods Used Participants diagnosed with TMD due to disc displacement were divided into two groups: Group 1: Received a single injection of Triamcinolone acetonide every three weeks. Group 2: Took Naproxen (550 mg) twice daily for three weeks. Pain levels and mouth opening were measured before and after the treatment period. Key Findings A total of 80 patients participated in the study, with a majority being female. After three weeks: Pain Reduction: Group 1 reported a mean pain score of 4.18, while Group 2 had a lower score of 2.65. Mouth Opening Improvement: Group 1 improved to an average of 34.93 mm, compared to 32.28 mm in Group 2. Both results showed that corticosteroid injections were significantly more effective than NSAIDs. Conclusion Corticosteroid injections are more effective than NSAIDs for pain relief and improving mouth opening in TMD patients. Practical Solutions and Benefits Clinical trials like this are essential for developing effective treatments. Implementing findings into everyday practice can enhance patient care. DocSym, our AI-powered platform, offers: Consolidated access to clinical protocols and research. Mobile apps for scheduling, monitoring treatments, and telemedicine. By leveraging AI, clinics can streamline operations, improve patient outcomes, and reduce reliance on paper processes. Learn more about how we can assist at aidevmd.com. https://lnkd.in/gg-Vum4C #ClinicalTrials #AIinHealthcare #MedicalAI #HealthTech #DigitalHealth #PatientCareAI #AIResearch #MedicalInnovation #BioTech #AIforGood #HealthcareData #AIinMedicine #PharmaAI #ClinicalData #HealthAI #AIHealthSolutions #PrecisionMedicine #AIandHealth #ClinicalAnalytics #AIDiagnostics