Viola Fernandes’ Post

I am pleased to present our research published in the 'Journal of Photochemistry and Photobiology A: Chemistry'. We have investigated the impact of regioisomers on differential aggregation-induced emission behavior and selective copper ion sensing in both solid and solution phases. The study highlights the compound's versatility and potential for multipurpose applications, including bioimaging and real sample analysis. Here is the link to access the article: https://lnkd.in/eTT9TM9X

🔬 Groundbreaking Discovery in Synthetic Organic Chemistry! 🧪 I’m thrilled to share that a team of innovative chemists has successfully synthesized an "impossible bridge head double bond," a milestone achievement recently published in Nature. This breakthrough challenges longstanding theories and paves the way for novel approaches in molecular design and synthesis. Why This Matters: Innovative Chemistry: Creating bridge head double bonds was previously deemed unattainable due to inherent molecular constraints. This success showcases the remarkable advancements in synthetic chemistry. Potential Applications: This discovery could revolutionize fields such as pharmaceuticals, materials science, and organic electronics by enabling the development of more stable and versatile compounds. Future Research: Opens new avenues for exploring complex molecular architectures and understanding reaction mechanisms at a deeper level. Kudos to the research team for their perseverance and ingenuity in achieving what was once thought impossible. This is a testament to the endless possibilities that lie at the intersection of creativity and scientific rigor. 🔗https://lnkd.in/gN9vWRek. #Chemistry #ScientificBreakthrough #ResearchInnovation #MolecularScience #NaturePublication #OrganicChemistry #Pharmaceuticals #MaterialsScience #Innovation #ScienceCommunity

Last week, I had the pleasure of presenting my master’s thesis project in the field of biomaterials. Over the past two years, my primary focus has been on exploring the effect of polymers and small molecules on the formation of organic crystals. This presentation marks a significant step in my academic journey, as I am continuing directly to a PhD. #MscThesis #PhDLife #BioMaterials #Polymers #OrganicCrystals

On this day in science Karl Alex Müller was born Müller was a Swiss physicist who shared (with J. Georg Bednorz) the 1987 Nobel Prize for Physics for their joint discovery of superconductivity in certain substances at higher temperatures than had previously been thought attainable. They startled the world by reporting superconductivity in a layered, ceramic material at a then-record-high temperature of 33 degrees above absolute zero. Their discovery set new research worldwide into related materials that yielded dozens of new superconductors, eventually reaching a transition temperature of 135 kelvin. #science #scienceandtechnology #organicchemistry #biotech  #scienceandcommunication #synthesis #organicchemistry #superconductivity #chemotherphy #sciencecommunication #chemistry #chemical #biochemistry #medicalsciences #chemicalindustry #pharmaceuticals #nobelprize #research #infographic via Compound Interest | Chemistry infographics

At the end of my PhD, we initiated a campaign on a photoenzymatic process using red light to catalyze radical reactions, which has now been published in Chem Cell Press. Photoenzymes, a class of biocatalysts using photonic energy, have gained attention due to their latent photochemical functions. In this field, there is a need to spectrally tune the photoenzymatic chromophore to improve enzyme stability and scalability. We engineered a flavin-dependent "ene"-reductase to utilize red light for a radical cyclization, previously achieved with cyan light. By targeting residues throughout the protein, we optimized its red-light activity, scaling the reaction to 10 grams. Mechanistic studies revealed that protein engineering alters substrate-binding conformations, resulting in red absorptions. Surface mutations further tuned the light-absorbing complex, revealing allosteric regulation in artificial photoenzymes, a novel discovery. This work demonstrates the potential for tuning photoenzymes with directed evolution, advancing chemical manufacturing. Now all my PhD works are concluded. Congratulations Jose et. al https://lnkd.in/gQcYKYKM

I am sharing my recent publication: the paper "Numerical and experimental investigation of chaotic advection and diffusion mixing effects in 3D multihelical microfluidics for liposome synthesis" published on Chemical Engineering Science. https://lnkd.in/ddC_hT7e

💡 [ 🔎 Scientific article 🔍 ] 💡 Multibranch Elastic Bound States in the ContinuumAn innovative synthesis of carbon-coated TiO2 nanoparticles as host for Na+ intercalation for sodium‑ion batteries ✍ Authors✍ Tanguy Soudant, Solenne Fleutot, Stéphanie Bruyère, Lucie Speyer, Sébastien Hupont, Mickaël Bolmont, Thomas Girardet, Loris Raspado, Claire Hérold, Sébastien Cahen 📰 References 📰 Dalton Transactions (2024) Intercalation Compounds themed collection 👀 Link 👀 https://lnkd.in/ebmYHSw9 📖 Abstract 📖 This collaborative work has been carried out as part of the B@tteriesIJL project and was also supported by the ORION program (Osez la Recherche par la FormatION; LUE funding ANR-20-SFRI-0009). This research involves the IJL teams “carbon materials”, “DOLPHIN: Nano-Bio-Materials for Life” and “Thin Films for Energy and Applications”. The goal is to develop new anode materials for sodium-ion battery technology. In this work, an innovative route to synthesize anatase TiO2@C composite is presented. The synthesis was conducted by a soft chemistry microwave-assisted method using titanium(IV) butoxide as both titanium and carbon precursor. Indeed, we use the residual (un)converted titanum precursor remaining after TiO2 synthesis as carbon precursor by a thermal treatment under H2 to obtain nanoparticles of TiO2 nanoparticles coated with a protective carbon layer. After characterization of the material, we use dit as anode and show a superior reversible specific capacity with TiO2@C than raw TiO2. This result highlights the importance of carbon coating addition with TiO2 nanoparticles in order to be used as negative electrode material for sodium-ion batteries.

Have a look at my latest animated cover design inspired by Max von Delius's team's research on chiral nanohoops as asymmetric organocatalysts! This study explores the integration of a BINOL-derived phosphoric acid into a cycloparaphenylene (CPP) nanohoop scaffold, creating a unique confined reaction environment for asymmetric catalysis. In this paper, they have made significant strides in enhancing the efficiency and selectivity of chemical transformations using this novel approach. Key highlights from the article: ⏣ A chiral nanohoop catalyst was synthesized, achieving remarkable catalytic activity with near-quantitative yields and enantioselectivities up to 96% ee in asymmetric transfer hydrogenation of quinolines. ⏣ The nanohoop catalyst demonstrated superior performance compared to non-cyclic reference catalysts, showcasing the potential of confined reaction spaces in organocatalysis. ⏣ Unexpected substrate selectivity was observed, with the catalyst showing high activity for aromatic substrates but low reactivity towards alkyl-substituted quinolines, indicating specific non-covalent effects within the nanohoop cavity. This is the way toward new designs of structurally complex organocatalysts with enhanced selectivity. I am already excited to see how this work will influence future developments in asymmetric organocatalysis and supramolecular chemistry! Co-authors: Adriana Sacristan Martinín, Fabian Schwer, Thomas Pick, Anika Lebzelter and Alexander Pöthig Ulm University ⌬ Technical University of Munich #sciart ⌬ #research ⌬ #chemistry

PhD Fellowship in Chemistry A PhD Fellowship in Chemistry is available in the Catalysis and Sustainable Group (https://lnkd.in/gapjrWRQ) at the Basque Center for Macromolecular Design and Engineering, POLYMAT Fundazioa (www.polymat.eu) in collaboration with an industrial partner. The focus of this PhD thesis will be in valorization of Acrylonitrile butadiene styrene (ABS) using innovative approaches.

Chemistry Insight: Bredt's Rule—And a New Breakthrough! It’s not often we get news like this that changes the way Chemists view established principles. UCLA chemists have recently expanded our understanding of molecular stability and reactivity in ways previously thought impossible. This breakthrough could open up new pathways for designing complex molecules and advancing Drug Discovery, which could be big news for future research. See link in comments! #Scientificdiscovery #Chemistry #Science