Vladimir Kubyshkin’s Post

Insightful review on proline analogs.

Ladderanes are innovative 3D-shaped scaffolds occupying rather compact molecular volumes, making them perfect substituents for screening. In addition, [2]-ladderanes demonstrate an isosteric relationship to substituted aromatics with remarkably close geometric resemblance. Our chemists have prepared a series of unique ladderanes for exploring their potential in medicinal chemistry: https://bit.ly/3yIExpp Try our ladderanes in your research!

I am excited to share that part of my PhD dissertation research has been published in ACS Food Science and Technology! If you want to learn more about the chemistry and crystallization of butteroil, enjoy!

How can we turn HTS lemons into lemonade? Check out our new work (with talented undergraduates Thu Nguyen and Chloris Li-Ma) in ACS Chem Bio using HTS to identify turn-on fluorescent dyes to characterize protein state. https://lnkd.in/gnRtNHRR

I want to take a moment to express my gratitude to Ulrich Luecking for sharing this highly informative post. The topic concerns a fascinating and innovative chemical process called the Rh(III)-catalyzed spiro-annulation. This particular method involves the reaction of sulfoximines with maleimides, and the outcome of this reaction is the diastereoselective synthesis of intricate spirocyclic-1,2-benzisothiazole heterocycles. This approach is intriguing because it beautifully integrates the formation of five-membered spiral molecules that contain essential elements like nitrogen and sulfur, all achieved in a single step. This enhances the reaction's efficiency and showcases the versatility and potential of spiralcyclic compounds in various applications. The ability to synthesize such complex structures straightforwardly opens up new avenues for research and development in organic chemistry.

https://lnkd.in/gpmYdqqz Please watch it once and subscribe my channel. This channel is all about chemistry. like , comment and share

Check out our latest publication in Chemical Science! Here, we detail the use of aliphatic alcohols as radical precursors for the stereoselective synthesis of unnatural α-amino acids.

Right now, the big push in 2024 chemistry Nobel prize winner David Baker's lab is for enzyme design. We can't wait to see what new developments in the field they make! See more from Paul T Kim, David Baker, and more chemistry experts in the aftermath of protein structure prediction winning this year's Nobel prize in chemistry by watching our webinar: https://lnkd.in/g_4zUPXm

Congratulations to Dr. Drew Budner, professor of chemistry, for his recent publication titled, “Influence of Ethanol Concentration on the Extraction of Cannabinoid and Volatile Compounds for Dry-Hemped Beer.” This study was designed to determine the influence ethanol concentration has on the cannabinoid and volatile compounds found in beer. To read the publication, visit https://lnkd.in/eNiWuT8M. Way to go, Dr. Budner!

Speaking of NMR, a new paper has been published in Food Chemistry. It explores the use of various high-field NMR techniques to identify the origin of different commercial teas. https://lnkd.in/dxi85teV