Wellcome Connecting Science Learning and Training’s Post

A new framework has been developed to help healthcare workers better educate families about genomic medicine.   Two new studies led by Murdoch Children's Research Institute (MCRI) and Australian Genomics researchers Associate Professor Amy Nisselle and Bronwyn Terrill aim to improve genomic medicine education for healthcare professionals that will hopefully provide better health outcomes for children and families.    Associate Professor Nisselle and collaborators have developed an evaluation framework that can be used across a range of educational programs and clinical settings drawn from 20 years of literature.   Read more: https://lnkd.in/gCN84Vqt To access the second publication, please click on the link provided in the first comment below. #Genomics #GenomicMedicine #Education

Crafting Science Stories for Young Audiences In his laboratory at the Department of Pathology, University of Cambridge, immunologist Adrian Liston studies the complex inner workings of the immune system with a focus on regulatory T cells that help keep the body’s immune response in check. But beyond the bench, he whittles down the jargon-filled, methodical, and nuanced research and transforms it into digestible nuggets of scientific communication for young audiences. https://lnkd.in/eA6z2Y2e

This post and article from the Director of the NIH (National Institutes of HEALTH) remind us that the true mission of this federal agency is "to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability." https://lnkd.in/gXMQUZSP Seeking fundamental knowledge about living systems actually comes first in the official mission statement of the NIH, and application of such knowledge to health is more of a consequence/byproduct of this.

Scientists Silencing Science: The True Harm in Dismissing the Lab-Leak Hypothesis Ignoring the Lab-Leak Hypothesis Undermines Science and Public Health. Of Course Individual Scientists Working on Pathogens Must be Held Accountable with Oversight to Discourage Lab Leak Pandemics James Lyons-Weiler Aug 21, 2024 On August 1, 2024, a group of 41 authors published an article(1) asserting that promoting the lab-leak hypothesis for the origins of SARS-CoV-2 is harmful, branding such exploration as "anti-science" and devoid of evidence. These authors, many of whom hold significant influence in the field of virology and who would likely see career changes if gain-of-function research is canceled, sought to reinforce the prevailing narrative of a natural zoonotic origin, dismissing the lab-leak theory as a dangerous distraction. However, this stance is not merely a rejection of an alternative hypothesis—it is a calculated attempt to silence debate and undermine the fundamental principles of scientific inquiry. The Kennedy Beacon Gain-of-Function Research Must Be Banned: The Faucis of the World Cannot Be Trusted with a Moratorium “It’s now obvious that Covid started as a lab leak. That fact was deliberately suppressed by Anthony Fauci and his cronies, with the complicity of the bioweapons research community. We have to stop this kind of research NOW… Courageous Discourse™ with Dr. Peter McCullough & John Leake https://lnkd.in/gywyQwax

Curious about the role of genomics in cardiovascular health? The American Heart Association has an essential resource to guide healthcare professionals through the latest in Cardiovascular Genomics. From understanding genetic risk factors to integrating genomic data into patient care, this guide is packed with valuable insights. Explore topics like: •. Genetic testing for heart conditions • Genomics in personalized medicine • Best practices for patient management Dive into the full guide here: https://lnkd.in/eT_93qqG

For his senior thesis project, Metch Nelson ’25 is researching the disparities in healthcare in the context of large-scale genetic research programs. “My research focuses on the All of Us Research Program, a large-scale genetic initiative designed to accelerate precision medicine by collecting diverse health data from one million or more participants across the US.” “I am specifically examining the program’s history, motivations, leadership, participant engagement, and challenges, with an emphasis on understanding and addressing the lack of diversity in genomic datasets.” “My passion for equitable healthcare access arose because of my family’s Haitian background. The realization that underrepresented communities are often excluded from genetic research resonated with me.” At BUA, the Senior Thesis is a culminating experience for all students. With the guidance of a Boston University professor, students create an independent research project that provides them with the opportunity to follow an intellectual passion in depth. The year-long project is designed to demonstrate a student’s ability to read closely, research thoroughly, think analytically, and write coherently in a scholarly fashion. Read the full article here: https://lnkd.in/esH6egXp

𝐄𝐱𝐜𝐢𝐭𝐢𝐧𝐠 𝐧𝐞𝐰𝐬 𝐟𝐫𝐨𝐦 𝐂𝐨𝐥𝐮𝐦𝐛𝐢𝐚 𝐔𝐧𝐢𝐯𝐞𝐫𝐬𝐢𝐭𝐲 𝐈𝐫𝐯𝐢𝐧𝐠 𝐌𝐞𝐝𝐢𝐜𝐚𝐥 𝐂𝐞𝐧𝐭𝐞𝐫! The newly launched #Biobank Resource for Investigating Disease, Genes, and Environment (BRIDGE) facility is set to revolutionize biomedical research. With the capacity to store up to 12 million patient samples and an $8M NIH grant, BRIDGE offers cutting-edge storage and integrates patient data to accelerate discoveries. This centralized resource is a game changer for researchers—especially early-career scientists—by providing easier access to diverse and high-quality biospecimens. It also serves a diverse patient population, with a focus on reducing health disparities and promoting health equity. Click here to learn more about how the BRIDGE facility is advancing biomedical research and health equity: https://lnkd.in/dQSti7Va Columbia University Irving Medical Center | Michael Shelanski | Azenta Life Sciences | Aaron Viny | Columbia University | The National Institutes of Health #Biobanking #Biorepository #Biomedical #ColumbiaUniversity #BRIDGE #MedicalResearch #HealthData #Cryopreservation #Databank

🔬 Exciting News for Scientists! 🔬 Introducing: Nature Springer’s Borrelia burgdorferi: Methods and Protocols. Methods in Molecular Biology. Editor Leona Gilbert. https://lnkd.in/dyW8d6V6 📚 From cell and molecular biologists to statisticians and clinical researchers, these methods cater to all fields. Explore techniques for in vitro, in vivo, in situ, de novo, and clinical studies of Borrelia burgdorferi. Let's advance our understanding of infectious diseases! 💪🌍 Chapter 13 Revealed. Exploring Tick-Borne Diseases Through Content Analysis: A Tutorial from Prof. Stephen M Croucher How do social media platforms influence the public's perception of tick-borne diseases? Content analysis provides a structured, systematic approach to uncover this. In his latest chapter, Prof. Stephen M Croucher delves into the intricate ways tick-borne diseases are portrayed across social platforms like Twitter. These spaces aren't just where conversations happen—they're battlegrounds for shaping the political, social, and health narratives surrounding these diseases. Join Prof. Stephen M Croucher in a tutorial where we will navigate through the complexities of social media content, learning how to qualitatively and quantitatively infer the sentiments behind the messages. Thejourney will equip you with the tools to conduct your own content analysis, enabling you to participate in the broader dialogue with informed insights. #TickBorneDiseases #ContentAnalysis #PublicHealth #SocialMediaResearch #LymeDisease #InnovativeResearch #TickborneDisease

🚨 Exciting News! 🚨 I’m happy to announce that our latest research article, "Identification of Kidney Cell Types in scRNA-seq and snRNA-seq Data Using Machine Learning Algorithms," has been published in Heliyon! 🎉 🔗 You can access the full article here: https://lnkd.in/g-tuq6Z6 In this study, we compared the performance of five machine learning algorithms using publicly available scRNA-seq and snRNA-seq datasets to develop a more robust and accurate method for annotating kidney cell types. This work could play a crucial role in future studies that aim to identify disease pathways and molecular targets in the kidney, paving the way for improved therapeutic interventions in kidney-related diseases. 💡🔬 A special thank you to my collaborators and co-authors (Adam Tisch & Siddharth Madapoosi) for their dedication and hard work over the course of this project, including colleagues from: University of Michigan, Ann Arbor, MI, USA University of Washington, Seattle, WA, USA Joslin Diabetes Center and Harvard Medical School, Boston, MA, USA Johns Hopkins School of Medicine, Baltimore, MD, USA Leiden University Medical Center & Delft University of Technology, The Netherlands You can find more about the project and access the code on our GitHub page: 🔗 GitHub Repository https://lnkd.in/gP6Q9QY9 I look forward to hearing your thoughts on our work and how it might contribute to the broader field of computational biology and kidney disease research! #KidneyResearch #MachineLearning #scRNAseq #snRNAseq #Bioinformatics #Research #Publication #OpenAccess #TeamScience #Heliyon #ComputationalBiology

One of the world's leading scientists in Parkinson’s and Alzheimer’s research may have fabricated images in at least 132 published papers between 1997 and 2023. This manipulation of data doesn’t just betray scientific integrity—it erodes trust, wastes funding, and endangers the very lives of those we are sworn to protect: people affected by these diseases. When research is molded to fit a narrative rather than to question it, the real victims are the patients who depend on our pursuit of truth for survival. The papers of this scientist have accrued over 180,000 citations together, exerting a gigantic influence on Alzheimer's and Parkinson's research. It’s time for humility and reckoning. No matter how compelling our ideas may seem, if they are false, they will fail. Much of the Alzheimer’s and Parkinson’s research pipeline may be resting on a house of cards. https://lnkd.in/gEJy-p2i