Xploregen Discoveries’ Post

Across the 8.7 million living species on planet Earth, DNA and RNA form the cornerstone of life. This foundational aspect makes the study of DNA and RNA not just fascinating but essential. On 16 May, join our experts, Tan Qi An and Naatasha Isahak, as they guide you through an enlightening exploration of DNA and RNA analysis. Get ready to delve into essential techniques and analysis solutions, exploring how these tiny molecules have a profound impact across diverse fields, including pharmaceuticals, food safety, medical diagnostics, and forensic investigations. Discover the power of DNA and RNA analysis with us! Register now: https://lnkd.in/gbRGphhy #Shimadzu #ExcellenceinScience #DNA #RNA

Here Miller et al describes a very practical use of charge determine mass spectrometry for the determination of linearly state of mega Dalton pasmide DNA 🛎Overview: Plasmid DNA is a critical component of oligonucleotides based vaccines. Supercoiled plaside DNA is the preferred industry standard ( >90%) as it has the highest actitry. But plasmid DNA can exists in other from such as, relaxed (circular), linearized, and condensed. But with lower activity and not prefer by industry. Here Miller et al employed a CDMS assay to determine and plasmid DNA structures 🎯Summary: Work with electrospray MS revealed two main structures supercoiled and condensed. Where as Miller et al observed that all all four structural types for plasmid DNA have unique charging #massspectrometry #massspec #vaccines #vaccineswork #science #scienceandtechnology #chemistry #pharmacy #biotherapeutics #biopharma #processmonitoring #dna

Polymerase Chain Reaction (PCR) is a technique to make millions of copies of a specific DNA segment. It involves three main steps: denaturation (separating DNA strands), annealing (binding primers), and extension (synthesizing new DNA). PCR is used in research, forensics, and medical diagnostics to amplify DNA for various purposes. #PCR #PolymeraseChainReaction #DNA #Copies #Annealing #Denaturation #Extension #Amplify #Bioinformatics #Biotechnology #Lifescience

We just published a new R/Bioconductor package for correcting gDNA contamination in RNA-seq data, CleanUpRNAseq, in BioTech: https://lnkd.in/e_dAWBnV. This package provides a comprehensive suite of functions for detecting and correcting gDNA contamination in bulk RNA-seq data.

Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition A new mass spectrometry strategy combines the advantages of data-dependent and data-independent acquisition. https://lnkd.in/gte5nt9m

Hi Connections! Here I am excited again to announce another publication of our latest review article in IIUM Revelation and Science, titled “DNA Aptamers: The Game Changers in Diagnostics” Paper Highlights: - High Accuracy: Selected through SELEX or in silico SELEX, aptamers bind with specific targets to form aptamer-target complexes. - DNA Aptamers: Preferred over RNA aptamers for their stability and capacity for chemical modification. - Cost-Effectiveness: Aptamers make diagnostics more accessible and affordable, facilitating large-scale production and the development of point-of-care testing (POCT) kits. - Structural Insights: The paper delves into fundamental structures and motifs of DNA aptamers, such as hairpin, G-quadruplex, and pseudoknot. - Diagnostic Platforms: Highlights the potential of aptamer-based diagnostics in detecting various diseases and addresses the challenges faced by DNA aptamers. You may read the full article here: https://lnkd.in/gCRm2sZp Feel free to connect for more insights or collaboration opportunities! #izzatsuffian #izzatkongsi #Diagnostics #DNAaptamers #Biosensors

Recovery of biological signals lost in single-cell batch integration https://lnkd.in/d4bd_VHd

In need of a high quality Reverse Transcriptase for your next project? Varizymes offers several that are lightning fast, thermotolerant and at a significantly lower price than our competitors! Learn more about what we have to offer at https://lnkd.in/g5SRp9mx #reversetranscriptase #polymerase #moleculardiagnostics #pcr #rna #dna #cdna #amplification

Glad to share with you that i had successfully completed a comprehensive #Molecular Diagnostics #training course for the period from Sep 16th 2021 until Dec 25th 2021, and has the ability for RNA #extraction by MGISP-960 platform, #qPCR testing and #data analysis

#ProductFocus . Looking for a solution to streamline your pathogen DNA isolation process? Look no further, here is MolYsis™. 🌟 Key Facts: 1️⃣ Up to 99% Host DNA Depletion: Say goodbye to interference from host DNA with MolYsis™, which efficiently removes up to 99% of host DNA from the sample, ensuring a sensitive detection of the pathogen. 2️⃣ Versatile Workflow Options: Whether you prefer manual or automated workflows, MolYsis™ offers flexibility to suit your laboratory's needs, enhancing convenience and efficiency. 3️⃣ Proven Track Record: With over 800 publications, MolYsis™ is an established technology, extensively used and trusted in many research & clinical laboratories. 🚀 Why MolYsis™? - High pure reagents in combination with host DNA depletion: Achieve highest purity of your pathogen DNA and enhance the accuracy of your downstream analysis. - Optimize your workflow with customizable options for manual or automated processing. - Join a vast community of researchers and clinicians benefiting from the proven success of MolYsis™ technology. Ready to elevate your research or diagnostic capabilities? Contact us today to learn more about MolYsis™ and revolutionize your pathogen DNA isolation workflow! More info on: https://lnkd.in/dG42wQR2 #Molzym #PathogenDNAIsolation #MolYsis #ClinicalResearch #MolecularDiagnostics