Zimmer and Peacock Ltd’s Post

Transcript

Question #9 I was asked, you know, how would one translate to paper like this into a actual product that could be used outside of the lab? And this is a good one because actually they're trying to detect nitrates in soil. And just FYI, mean at ZP we do, you know, when I talk about when I'm talking about nitrates, we do have quite a lot of experience of nitrates. In fact, we have a nitrate sensor. Just trying to think what? Yeah, So we do have. And like treats. Yeah, I do have it on here as well. Good. Whoops, Daisy, wrong one and but we do have a nitrate census one of the QR codes that we have on the device. Let me just go back to here. So I'm going to talk here about translating into an actual product. So there are few things that the first thing I notice is that this is using open circuit potential ometry. So if I go back to how we would translate this into a product. We do have open circuit potentiometry available on this. We are able to. We have, we have all the superficial mature on this. So we are able to then drive the device through Bluetooth from the app. So I do want to actually make Bluetooth to connection with this guy. There we are. So I'm connected now. So now I've done opposite potentiometry. I'm in Bluetooth connection with the device. I know I'm now in connection because this was a flashing blue light. Now it's a white light. At which point then they want to do OCP, which is great because that's one of the techniques that we have, one of the techniques we use quite regularly. I'm just going to go back to this screen here. So they're using open circuit potential ometry and they describe how they do their particular assay. Now, many of our scooby-doo lecturers at ZPR 3 electrode systems, but the, the potential stats are smart. So when somebody's trying to do a OCP measurement, they may only need 2 electrodes and the device will essentially only measure the potential between two of our electrodes. It knows how to do it automatically. You don't have to program it. So I'm, I'm only using, I'm first of all, I'm referencing when I got this from and I'm only using the images really to kind of. Illustrate how we would translate a paper like this actually into a product O What we would do is take would probably take the 501 carbon electrodes, functionalize it with their nitrate specific film or polymer. They also put a napkin layer over the reference electrodes. So as I say, the potential stat, we don't need the counter electrode in this particular case. But the potential stat is smart enough that in when OCP mode, it will know even though I've got 3 pins in this particular device, it will know to actually only use two of the pins and it knows which 2 pins to use. It uses our working electrode and our reference electrode because we're very consistent in that when we're sort of programming the devices and the way we do. Acid development. So if I was translating this into, let's say into something that I could scale up and give out to give out to other people, Nathan on here. And then they do have this interesting extra layer that they put on here, which is PVDF. And as I say, if I was kind of just do a quick summary demo, which I will do here. Let me just think when I'm going here. Right. OK. So we've got something A501 carbon Electra which has a circular electrode. It's not this one. So the circle Electra is quite good because they can functionalize that quite readily. They can put the, you know, Nathan on the reference, their nitrate cocktail on the working and they can add that extra layer of I think it's peak called PVDF on there. And essentially that point they made their bio sensor then to actually run the assay they can use. You're super potential metering modes. They can then. I'll just do that anyway. This will give me rubbish. I actually put, I haven't actually put a liquid sample on there, but it will essentially run that and then when it's run, it will actually upload the data straight to the cloud system that we got earlier on. Now I'm showing you here psycho photometry data, but this can receive photometry data, linear sweep voltammetry data, square wave altimetry data, EIS voltammetry data, OCP over circuit potential, metric data and perimetry. And then actually they can put their OCP data. Again, through the data pipe. Now in their case, they're not looking for peak hike, they're probably just going to do a sort of measure the potential at the certain time kind of by the way that's uploaded the data to the cloud. They can come up with their own calibration routine. And in fact, that is a good point for me to translate, not translate, but transition because in fact, with these kind of papers, they often have already done the calibration. So it's definitely what we're, you know, what we're trying to help the academic community do is actually get from a proof of principle like this a TRL. Three, where you did the testing in the lab to two URL 5, you know, where you can actually take it out of the lab and actually put it into the, let's say, the into the real world. And it again, I mean, this is something that we started doing 7 years ago. We actually turned this particular paper, let's say, into a product. And I say and, and it does again, part of this, how do we convert more paper, especially things like nitrate in soil, which is a real, let's say problem. And therefore, you know, the market is. The market is self identifying, governments are very interested in this. You know, if we wanna reach kind of net zero in the world, nitrate is a good place to start because I think 1.2% of global CO2 probably comes from nitrate production. So it's a good target. You wouldn't have to persuade many people that this was actually a good idea. If you're interested in this kind of work or this kind of translation, then do come along to the web and are on the 10th of December.