Application of bile acids in diets without additional fat

The fat in the feed can not only provide the animal with essential fatty acids, but also an important source of energy. It can be effectively converted into animal body fat, improve growth performance and slaughter performance, and is an indispensable part of animal nutrition. However, affected by the Russian-Ukrainian war, the price of feed raw materials continued to rise, feed factories and farms were under huge cost pressure, and the price of soybean oil continued to rise.

At present, in some Muslim countries, such as Egypt, the use of animal fats and oils is prohibited, and only vegetable oils can be used. As the main source of fats and oils in poultry feed, soybean oil has recently soared and cost performance has decreased. Feed mills have chosen to use high-fat raw materials or soybeans to replace oil, reducing or zero-adding soybean oil.In this case, will the effect of bile acid be fully exerted?

The answer is yes. First of all, if no additional oil is added, the source of fat in the diet is mainly the oil wrapped in the raw material, such as corn, soybean, soybean meal and other feed materials. Fat is insoluble in water, and if it is not used properly, the precious fat in the diet cannot provide enough energy for poultry, affecting its performance and the body's absorption of fat-soluble vitamins and pigments. The addition of bile acids can improve the utilization rate of fats and oils in the feed, because bile acids are the only substances in vertebrates that promote fat digestion and absorption, and play a full role in the three stages of emulsification, digestion, and absorption. Its mechanism of action is:

Emulsification stage: emulsify fat particles into fat particles, increase the contact area between fat and lipase, thus creating conditions for lipase to decompose fat;

Digestion stage: activate the activity of lipase and promote the digestion of fat by lipase;

Absorption stage: fatty acids and bile acids form mixed particles, carrying fatty acids, so that fatty acids are recognized by small intestinal epithelial cells and smoothly enter the small intestinal villi to complete the fat absorption process.

Secondly, the alternative raw materials contain more anti-nutritional factors, such as adding soybeans, so that the anti-nutritional factors such as trypsin inhibitor, tannin, β-hemiglobulin, phytic acid, urease, etc. accumulate in the feed, which will lead to intestinal inflammation and liver damage. Moreover, soybeans contain a polypeptide component that can combine with bile acids in the intestinal tract, and the combined bile acids will be excreted with the feces, resulting in the loss of bile acids, the reduction of the digestion and absorption rate of energy in the feed, and the deterioration of the quality of the feed. Adding bile acids can solve these problems. Its mechanism of action is:

Through enterohepatic circulation, bile acids can stimulate the liver to synthesize new bile acids, promote the secretion of a large amount of thin bile by hepatocytes, make the bile ducts unblocked, eliminate bile stasis, play a choleretic effect, relieve the burden on the liver, and maintain the normal function of the liver.

In addition, bile acids can degrade intestinal toxins, / mycotoxins / heavy metals, etc., combined with intestinal toxins that are not absorbed, to clean the intestines, reduce the burden of liver detoxification, and protect liver and intestinal health.

As an endogenous emulsifier, bile acid can replenish the lost bile acid and promote the digestion, absorption and utilization of fat in the raw material, which meets the needs of animals and is increasingly recognized by feed companies.

Below is a demonstration of the effect of bile acids on broiler performance performed by Lachance Group in Egypt.

Animals: 540 1-day-old AA commercial chicks with an average initial weight of 42g

Location：an integrated enterprise in Egypt 

Treatments：Randomly divided into 3 groups with 3 replicates per group, 60 chicks per replicate. The diet of Control Group was a corn-soybean-based basal diet, the diet of Test Group was 30 Kcal/kg less than the basal diet after adding 200 g/ton (with the cost of 40 EPS) Runeon (30% bile acids).

Conclusion: Adding 200 g/ton of bile acid to the 0-34 broiler diet reduces the metabolizable energy level of the feed by 30Kcal/kg, increases the weight gain of the broiler by 320 g, and reduces the FCR by 2.1%.

Summary：200g/ton, reduce the level of feed metabolizable energy by 30Kcal/kg, improve the production performance of broilers, reduce FCR, and improve comprehensive economic benefits.