Lab Notes Newsletter
Welcome to the February edition of our newsletter!
For 40 years, we’ve helped scientists harness the full potential of biology with next-generation technology. Here we share the latest in automated, end-to-end solutions that span research disciplines to advance scientific discovery and improve the quality of human life worldwide.
Danaher Launches Collaboration with Cincinnati Children’s Aiming to Improve Patient Safety in Early Drug Development
Danaher Corporation and Cincinnati Children's are teaming up with Molecular Devices to improve liver organoid technology as a drug toxicity screening solution. This multi-year collaboration aims to propel us towards safer drugs, faster therapies, and billions saved in R&D productivity.
A Three-Pillar Approach to Driving Organoid Adoption in Drug Discovery
Despite growing interest in using organoids for disease modeling and drug discovery, significant challenges remain in their development and broader use.
In this Biocompare article, our 3D biology experts Nikki Carter and Victoria Marsh Durban, Ph.D., share their views on what it’ll take to drive organoid adoption industrywide.
Automate the entire cell culture process to improve workflows and make assays more reliable and reproducible
The CellXpress.ai™ Automated Cell Culture System is an AI-driven cell culture innovation hub that gives your team total control over demanding cell culture feeding and passaging schedules—eliminating time in the lab while maintaining a 24/7 schedule for growing and scaling multiple stem cell lines, spheroids, or organoids.
Application Note: Get the most relevant data from valuable PDOs
Researchers need a better combination of models, biology handling systems, and assays to address the challenges in 3D biology drug treatment strategies involving resistance.
Read the app note to learn how lab automation was used to improve patient-derived colorectal cancer organoid workflows to develop efficient assays for compound testing applications.
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Application Note: Enhance the accuracy and efficiency of your oncology research
Malignant gliomas represent a formidable challenge in the realm of oncology due to their invasive nature and resistance to conventional treatments. As researchers strive to unravel the intricacies of these tumors, assessing the viability and understanding the real-time dynamics of apoptosis and necrosis in malignant glioma cells emerges as a crucial focal point.
In this application note, we showcase the utility of the CellTiter-Glo® 2.0 Cell Viability Assay paired with the SpectraMax® i3x reader, offering a powerful solution for the preliminary screening of compounds.
Application Note: Boost efficiency with precise Fc assay results
In this application note, we illustrate how the Fc PAIA Titer assay serves as a robust solution, offering fast, cost-effective, and automatable technology that caters to the biopharmaceutical industry’s quest for assays with streamlined workflows and minimal sample requirements.
This plate-based assay, designed for monitoring titers for Fc-containing molecules such as monoclonal antibodies, aligns seamlessly with the goals of bioprocess development.
Streamline your cardiotoxic compound detection with FLIPR® Penta
Traditional cardiotoxicity testing methods can take weeks or even months to complete, slowing down your research and drug development timelines. If you no longer want to rely on traditional, time-consuming, and costly methods for cardiotoxicity testing, we are here to help. Our state-of-the-art technology within the FLIPR® Penta allows for rapid and accurate cardiotoxicity assessment, enabling you to identify potential issues earlier and make informed decisions faster.
Eliminate line-frequency noise with a single mouse click
Electrical noise on a patch-clamp rig can arise from a variety of sources, including power supplies, computers, and fluorescent lights. Minimizing this noise is crucial for obtaining accurate recordings of ion channel activity and other electrical signals from biological samples.HumSilencer (HS) is a revolutionary feature within the Axon™ Digidata 1550B Data Acquisition System that provides a quick, adaptive method to remove such noise in one second with a single mouse click without distorting the data.
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