Prostate Cancer Discoveries Digest: August 2024

Welcome to your monthly edition of ZERO's Prostate Cancer Discoveries Digest! The latest information on treatment, diagnostics, and survivorship has been pulled from the headlines and delivered to your inbox!

ZERO Prostate Cancer does not endorse any particular article or finding that may be featured.

Survivorship

Neoadjuvant Exercise Therapy in Prostate Cancer

In this phase 1a trial, researchers examined the impact of various exercise intervals - from 90 to 450 minutes per week - to better understand the feasibility of the exercise program, changes in tumor cell proliferation, and PSA levels.

» Full article on JAMA Network

Health Equity

Neighborhood Disadvantage and Prostate Tumor RNA Expression of Stress-Related Genes

This observational study analyzed stress-related genes from Black and white men with prostate cancer to better understand the impact of living in disadvantaged neighborhoods on prostate cancer aggressiveness and outcomes.

» Full article on JAMA Network

Genetics & Genomics

Tumor Evolution Metrics Predict Recurrence Beyond 10 Years in Locally Advanced Prostate Cancer

This study used genetics, genomics, and AI to predict prostate cancer recurrence and outcomes.

» Full article on Nature Cancer

Outcomes

Prostate Cancer Biochemical Recurrence Prognostic Risk Factors

In a systematic review of 37 prospective studies, researchers aimed to better understand which risk factors led to a worse prognosis after biochemical recurrence.

» Full article on Renal+Urology News

Treatment

More Men with Advanced Prostate Cancer Could Be Successfully Treated with Precision Drug Olaparib

Researchers have identified a new genetic abnormality and target that may lead to more successful treatment with olaparib, an FDA-approved PARP inhibitor.

» Full article from The Institute of Cancer Research

Survivorship

Prostate Cancer Study: More Health Benefits from Plant-Based Diet

Eating more fruits, nuts, and vegetables each day along with fewer animal products is associated with a nearly 50% reduction in the risk of prostate cancer progression.

» Full article from the University of California San Francisco

Diagnostics

CMS Establishes National Payment for AI Breakthrough in Prostate Cancer Diagnosis, Unfold AI

The Centers for Medicare & Medicaid Services (CMS) has assigned a national payment rate for Avenda Health's innovative prostate cancer mapping technology, Unfold AI.

» Full article on PR Newswire

Survivorship

Temporal Trends in Medication and Service Use Patterns for Mental Health Issues Among Men with Prostate CancerCancer

Mental health outcomes of men with prostate cancer may be improved with early mental health screening, particularly during the diagnosis process, to enable early intervention.

» Full article from National Library of Medicine

Genetics & Genomics

Circulating Tumor Extracellular Vesicles to Monitor Metastatic Prostate Cancer Genomics and Transcriptomic Evolution

A new study shows that liquid biopsies may help monitor disease evolution in patients with metastatic prostate cancer.

» Full article on Cell Press

ZERO Prostate Cancer provides this information as a service. It is not intended to take the place of medical professionals or the recommendations of your healthcare team. Consult your healthcare team if you have questions about your specific care.

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