Supercharge Your Hit-to-Lead with Exquisite SAR & Accelerated DMTA

Congratulations on identifying promising hits for your drug discovery project! Are you ready to navigate the crucial Hit-to-Lead phase with confidence and precision?

At Arctoris, we're committed to accelerating your journey from promising hits to robust lead compounds. Our cutting-edge Ulysses™ platform and expert team are primed to tackle your Hit-to-Lead challenges head-on.

Comprehensive Hit-to-Lead Solutions

Our tailored approach covers every aspect of your Hit-to-Lead needs:

1. Rigorous Hit Validation: Confirm your hits with our suite of orthogonal assays, ensuring you're building on solid foundations.
2. Deep Characterisation: Leverage our advanced technologies for selectivity and kinetic profiling:
3. Complex Interaction Analysis: Quantitatively evaluate binary (protein-protein, protein-ligand) and ternary (protein-ligand-protein) interactions with unparalleled precision.
4. Structural Insights: Elucidate binding poses and establish high-throughput co-crystallisation platforms, processing 300+ ligands with ease.
5. Rapid DMTA Cycles: Accelerate your Design-Make-Test-Analyze loops with our integrated approach, constructing precise Structure-Activity Relationships (SAR) to guide your optimisation efforts.

Why Choose Arctoris for Hit-to-Lead?

1. Extension of your team: Our experienced scientists will be an extension of your team, working toward a shared goal and responding to data with agility and transparency
2. Unmatched Precision: Our Ulysses™ platform delivers consistently high-quality data, enabling confident decision-making.
3. Cutting-Edge Technology: Access a comprehensive suite of biophysical and biochemical assays without the need for costly in-house investments.
4. Seamless Integration: Our end-to-end capabilities ensure a smooth transition from hit identification through lead optimisation.
5. AI/ML Ready Data: Generate rich, systematic datasets perfect for training your computational models and driving rational design.
6. Flexible and Fast: Rapidly adapt to new findings with our agile approach, keeping your project ahead of schedule.

Real Impact, Real Results

Imagine characterising the binding kinetics of 100 compounds against your target protein in just 48 hours, with exquisite precision that reveals subtle structure-activity relationships. That's the power of Ulysses™ at your fingertips.

Our integrated Hit-to-Lead workflows have helped clients reduce timelines by up to 40%, while increasing the quality and quantity of data informing their lead selection decisions.

Partner with Passion

When you choose Arctoris, you're not just accessing world-class technology – you're collaborating with a team that's as invested in your success as you are. We'll proactively identify opportunities to enhance your Hit-to-Lead campaign, ensuring you're always at the cutting edge of drug discovery.

Ready to transform your hits into promising leads? Let's discuss how we can tailor our Hit-to-Lead expertise to your unique project needs.

We're excited to hear about your hits and show you how Arctoris can propel your project towards clinical candidates faster than ever.