AbbVie Contract Manufacturing

Engineers and scientists at AbbVie discover chemical processes that create molecules in a lab environment to create active pharmaceutical ingredients (APIs) to treat multiple diseases. That production process must be scaled up by several orders of magnitude for large-scale manufacturing. But, scaling up can be a challenge due to variability in both materials and processes. That's why to scale up, first our teams scale down to focus on Critical Quality Attributes (CQAs) and Critical Process Parameters (CPPs). That allows them to identify the path for scale-up, with a focus on creating a robust and efficient process. Learn more about scaling down to scale up, including safety, quality, and optimization. https://hubs.li/Q02ZT2wq0 #contractmanufacturing #cmo #apipharma #productmanufacturing #pharma #sciencefriday #funsciencefriday #science #pharmamanufacturing

AbbVie helps companies manufacture high-quality monoclonal antibodies for various therapeutic areas, including immunology, oncology and neurology. We have global antibody manufacturing capabilities with more than 85,000 L capacity, cGMP scale from 1,000 to 12,000L and a full development package including:  Process development  Analytical development  Late clinical transfer  PPQ efforts to post-commercial offering We’ve got you covered from process development through viral clearance studies and QA/QC to a successful BLA. https://bit.ly/495OnzT #pharma #biologics

Balance speed with precision. We’re committed to making biologics safe, reliable, and consistent. Download our cut sheet to learn more about how we prioritize both safety and manufacturing speed for large molecule biologics: https://bit.ly/3ZarvdE #biolgoics #biomfg #biointernational

Contract Manufacturing Organizations - or CMOs - can be standalone businesses that do not own products on their own. AbbVie CMO is an example of an embedded CMO - a self-contained enterprise that exists within a larger pharmaceutical company. AbbVie CMO is a strategic business unit within AbbVie Operations with 14 global manufacturing sites and commercial approvals in more than 180 countries around the globe. AbbVie Contract Manufacturing partners with companies across the globe to develop, scale and manufacture pharmaceutical products and successfully bring them to market by leveraging AbbVie’s technical and manufacturing expertise. Learn more about the benefits of CMOs and the difference between CMOs, CDMOs, and CROs. https://hubs.li/Q02Zc78q0 #contractmanufacturing #cmo #contractmanufacturingorganization #cdmo #productmanufacturing #sciencefriday #funsciencefriday #science #pharmamanufacturing

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We manufacture high-quality #mAbs. With global antibody manufacturing capabilities at more than 85,000 L capacity, cGMP scale from 1,000 to 12,000L and a full development package. We’ve got you covered from process development through a successful BLA. https://bit.ly/48Wbhtf

Tech Transfers are the method of bringing a product manufacturing process from one site to another. Tech Transfers can be initiated for several different reasons. They can help to increase the volume of production, to move production to a location with proximity to distributors, to assure supply by acting as a back-up, or to create network optimization. No matter the reason, translating a manufacturing process between sites requires assessment of many factors, from equipment to cost to safety. Learn more about Tech Transfers and how we identify the need for them at AbbVie. https://lnkd.in/er8BK_HS #techtransfers #contractmanufacturing #drugproductmanufacturing #sciencefriday #funsciencefriday #pharmamanufacturing

Which of these would make the biggest difference as you’re leveling up your custom API needs? ➡️ Process optimization and monitoring ➡️ Troubleshooting/investigations ➡️ Waste stream characterization ➡️ Tech transfer support ➡️ PPQ efforts ➡️ Raw material supplier evaluation Good news— at AbbVie CMO you have access to all those services and more. See how we help accelerate your API development and optimization: https://bit.ly/3Z2AFKq #pharmaceutical #manufacturing #customAPI

AbbVie makes your "vision" for your project possible with customized manufacturing. Whether you need ointment, multi-dose or united doses, AbbVie CMO offers complete customization for your product manufacturing outsourcing short.url/aBcXyZ #eyecare #pharmamfg

Fermentation is a process where organic molecules are broken down anaerobically - in the absence of oxygen. That breaking down is catalyzed by bioreactors like bacteria or yeast, which turn one substance into another. Industrial fermentation starts just like fermenting things at home. Even when we use our 2,000L tank or our 30,000 liter fermenter, we start with a "seed" - just like creating a sourdough starter! Learn more about fermentation, including the organisms we use and some of our sites pioneering single use bioreactors. https://lnkd.in/e_WdzCKr #fermentation #microbialfermentation #bioreactors #sciencefriday #funsciencefriday #science #pharmamanufacturing