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𝗥𝗼𝗰𝗵𝗲 𝗹𝗲𝗴𝘁 𝗚𝗿𝘂𝗻𝗱𝘀𝘁𝗲𝗶𝗻 𝗳𝘂̈𝗿 𝗱𝗶𝗲 𝗗𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗸𝗽𝗿𝗼𝗱𝘂𝗸𝘁𝗶𝗼𝗻 𝗱𝗲𝗿 𝗭𝘂𝗸𝘂𝗻𝗳𝘁 𝗶𝗻 𝗗𝗲𝘂𝘁𝘀𝗰𝗵𝗹𝗮𝗻𝗱: Roche legt den Grundstein für eines der modernsten Produktionszentren für qualitativ hochwertige diagnostische Einsatzstoffe Europas auf dem Campus seines Biotechnologie-Zentrums im oberbayerischen Penzberg. Dafür investiert das Unternehmen mehr als 600 Millionen Euro – die größte Einzelinvestition von Roche in Deutschland. Künftig sollen hier in einer hochautomatisierten und intelligenten Fertigung mehr als 450 essentielle Einsatzstoffe für diagnostische Tests für die Versorgung von Patientinnen und Patienten hergestellt werden. Mit dem Neubau stärkt Roche den Produktionsstandort Deutschland, erhöht langfristig die Versorgungssicherheit für In-vitro-Diagnostika weltweit und stärkt die Resilienz der Wertschöpfungsketten in Europa. Thomas Schinecker, CEO der Roche-Gruppe: „Heute legen wir den Grundstein für das modernste Diagnostik-Produktionszentrum Europas, um zukünftig noch mehr Patientinnen und Patienten mit innovativen diagnostischen Lösungen zu versorgen. Mit einer Investition von mehr als 600 Millionen Euro werden wir ab 2028 rund 450 verschiedene Einsatzstoffe für diagnostische Tests herstellen, die eine schnelle und zuverlässige Diagnose in den Bereichen Infektiologie, Neurologie, Kardiologie, Onkologie und Diabetes ermöglichen. Unser neues Produktionszentrum in Penzberg wird ein Symbol für Hochtechnologie und Nachhaltigkeit“ 𝗠𝗲𝗵𝗿 𝘂𝗻𝘁𝗲𝗿: https://lnkd.in/dhBcwMXr Roche Deutschland, Annett Fischer, MBA, Ferdinand von Reinhardstoettner, Dr. Markus Söder

𝗠𝗼𝗿𝗲 𝘀𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗲, 𝗳𝗮𝘀𝘁𝗲𝗿, 𝗰𝗵𝗲𝗮𝗽𝗲𝗿: 𝗖𝗵𝗲𝗺𝗶𝘀𝘁𝘀 𝗱𝗲𝘃𝗲𝗹𝗼𝗽 𝗴𝗿𝗮𝗽𝗵𝗲𝗻𝗲-𝗯𝗮𝘀𝗲𝗱 𝗯𝗶𝗼𝘀𝗲𝗻𝘀𝗼𝗿: Two-dimensional materials such as graphene are not only ultrathin, but also extremely sensitive. Researchers have therefore been trying for years to develop highly sensitive biosensors that utilise this property. Graphene-based field-effect transistors, for example, could register the tiniest changes in the electronic properties caused by the molecules when they interact with this atomically thin layer. However, the hypersensitivity of the material has so far stood in the way of the practical realisation of this idea. Scientists at Friedrich Schiller University Jena, Germany have now developed a solution to overcome this obstacle, potentially paving the way for a revolution in diagnostics. They have published their findings in the research journal "Advanced Materials". 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/euyQPiEq Friedrich-Schiller-Universität Jena, David Kaiser, Andrey Turchanin

𝗕𝗲𝗹𝗴𝗶𝗮𝗻 𝘀𝘁𝗮𝗿𝘁-𝘂𝗽 𝗕𝗜𝗢 𝗜𝗡𝗫 𝗮𝗻𝗱 𝗖𝗮𝗿𝗹 𝗥𝗢𝗧𝗛 𝗽𝗮𝗿𝘁𝗻𝗲𝗿 𝘁𝗼 𝗲𝘅𝗽𝗮𝗻𝗱 𝗮𝗰𝗰𝗲𝘀𝘀 𝘁𝗼 𝟯𝗗 𝗯𝗶𝗼𝗽𝗿𝗶𝗻𝘁𝗶𝗻𝗴 𝘀𝗼𝗹𝘂𝘁𝗶𝗼𝗻𝘀: BIO INX and Carl ROTH announced their new distribution agreement. This collaboration marks Carl ROTH’s first foray into the 3D bioprinting space, as the company continues its strategy of expanding into the rapidly growing 3D printing industry. Through this partnership, Carl ROTH will now offer BIO INX’s entire portfolio of bioinks, making these cutting-edge materials more accessible to researchers and scientists worldwide. This milestone enables Carl ROTH to complement its existing 3D printing portfolio with innovative solutions tailored for tissue engineering, regenerative medicine, and other bioprinting applications. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/eZh6mA68 BIO INX, Carl Roth GmbH + Co. KG, Lia Heiser, Jasper Van Hoorick, Oliver Lautenschläger

𝗦𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀 𝘂𝘀𝗲 𝗵𝗮𝗿𝗺𝗹𝗲𝘀𝘀 𝘃𝗶𝗿𝘂𝘀𝗲𝘀 𝘁𝗼 𝗶𝗻𝘃𝗲𝘀𝘁𝗶𝗴𝗮𝘁𝗲 𝘁𝗵𝗲 𝗻𝗲𝗿𝘃𝗼𝘂𝘀 𝘀𝘆𝘀𝘁𝗲𝗺 𝗶𝗻 𝗳𝗿𝗼𝗴𝘀: Amphibians hold a significant place in evolution, representing the transition from aquatic to terrestrial lifestyles. They are crucial for understanding the brain and spinal cord of tetrapods—animals with four limbs, including humans. A group of scientists led by a team at the Institute of Science and Technology Austria (ISTA) now shows how harmless viruses can be used to illuminate the development of the frog nervous system. The results have now been published in Developmental Cell. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/eW4rS5aY Institute of Science and Technology Austria, David V.. Lora B. Sweeney

𝗧𝗵𝗲 𝘀𝗲𝗰𝗿𝗲𝘁 𝗼𝗳 𝘀𝘁𝗮𝗯𝗹𝗲 𝗱𝘂𝘀𝘁: For small children, it acts like a protective elixir against asthma and other allergies from birth: the dust from the traditional cowshed. Researchers are keenly interested in exactly what causes this effect. However, deciphering it in terms of allergy prevention is a lengthy process, but one that has now taken another step forward: researchers at the Dr. von Hauner Children's Hospital at LMU Klinikum have analyzed how cells of the immune system react to cowshed dust and thus contribute to the "protective farm effect". The results were recently published in the journal "Allergy". 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/ejJVZ8PH Ludwig-Maximilians-Universität München, Dr. Michael Salvermoser, Franziska Sattler, Paulina Kulig, Vinko Toševski, Erika von Mutius, Claudia Beerweiler, Klinikum der Universität München Abteilung für Kinderklinik und Kinderpoliklinik im Dr. von Haunerschen Kinderspital, LMU Klinikum München, philipp kressirer

𝗡𝗲𝗿𝘃𝗲 𝗰𝗲𝗹𝗹𝘀 𝗼𝗳 𝗯𝗹𝗶𝗻𝗱 𝗺𝗶𝗰𝗲 𝗿𝗲𝘁𝗮𝗶𝗻 𝘁𝗵𝗲𝗶𝗿 𝘃𝗶𝘀𝘂𝗮𝗹 𝗳𝘂𝗻𝗰𝘁𝗶𝗼𝗻: The retina is often referred to as an “outpost of the brain” – after all, important steps in visual signal processing do not take place in the cerebrum, but in the nerve cells in the eye. When light falls on the retina, sensor cells become active and send electrical signals to layers of nerve cells located directly behind them. From there, signals are passed on to the brain. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/eYdK4W7t Technische Universität Wien, Guenther Zeck, Florian Aigner

𝗔 𝗴𝗿𝗼𝘂𝗻𝗱𝗯𝗿𝗲𝗮𝗸𝗶𝗻𝗴 𝗻𝗲𝘄 𝗮𝗽𝗽𝗿𝗼𝗮𝗰𝗵 𝘁𝗼 𝘁𝗿𝗲𝗮𝘁𝗶𝗻𝗴 𝗰𝗵𝗿𝗼𝗻𝗶𝗰 𝗮𝗯𝗱𝗼𝗺𝗶𝗻𝗮𝗹 𝗽𝗮𝗶𝗻: A research team at the University of Vienna, led by medicinal chemist Markus Muttenthaler, has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain. This groundbreaking innovation offers a safe, non-opioid-based solution for conditions such as irritable bowel syndrome (IBS) and inflammatory bowel diseases (IBD), which affect millions of people worldwide. The research results were recently published in the international edition of the journal Angewandte Chemie. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/eNFEsbYh Universität Wien, Markus Muttenthaler ,

𝗥𝗮𝗽𝗶𝗱 𝘀𝘂𝗰𝗰𝗲𝘀𝘀: 𝗶𝗻𝗻𝗼𝘃𝗮𝘁𝗶𝘃𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆 𝘀𝘁𝗼𝗽𝘀 𝗱𝗲𝗮𝗱𝗹𝘆 𝗯𝗿𝗮𝗶𝗻 𝗶𝗻𝗳𝗹𝗮𝗺𝗺𝗮𝘁𝗶𝗼𝗻: Progressive multifocal leukoencephalopathy (PML) is a rare but serious brain infection. It gradually destroys brain tissue and often leads to death within a few weeks. It is caused by the human polyomavirus 2 – also known as the John Cunningham (JC) virus. In 2021, an interdisciplinary team at the Hannover Medical School (MHH) led by Professor Dr Thomas Skripuletz, senior physician at the Clinic for Neurology with Clinical Neurophysiology, found a groundbreaking way to stop the virus from spreading. Since then, the clinic has been offering a treatment with new immune cells that can suppress the virus in the body of those affected. These directly isolated allogeneic virus-specific DIAVIS T cells come from the blood of healthy people who were infected with the virus. They have precisely fitting defence cells from the group of white blood cells. The T-lymphocytes recognise the attacking JC viruses as foreign to the body and initiate an immune response. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/eCkBCQgz Hannover Medical School (MHH), Professor Dr Thomas Skripuletz, Professor Dr. Britta Eiz-Vesper

𝗦𝘂𝗿𝗽𝗿𝗶𝘀𝗶𝗻𝗴 𝗘𝗳𝗳𝗲𝗰𝘁𝘀 𝗼𝗳 𝗮 𝗧𝘄𝗼-𝗟𝗶𝗽𝗶𝗱 𝗗𝗶𝗲𝘁: Lipids, or fats, are essential to life. They form the membranes around cells, protecting them from the outside. In nature, there is an enormous diversity of lipids, with each organism having its own unique combination. But what are the minimum lipid requirements for a cell to survive? A research team at the B CUBE - Center for Molecular Bioengineering at TUD Dresden University of Technology showed that cells can function with just two lipids. They created a cell with a minimal, adaptable membrane, offering a unique platform to study how lipid complexity evolved and how it can be engineered for synthetic life. Their findings were published in Nature Communications. Membranes are like bubbles that encapsulate cells and separate them from their surroundings. Membranes also serve as platforms where molecules interact, coordinating processes essential to life. 𝗥𝗲𝗮𝗱 𝗺𝗼𝗿𝗲: https://lnkd.in/e7wkTTWz Center for Molecular and Cellular Bioengineer­ing (CMCB) of TU Dresden, Technische Universität Dresden, James Saenz

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