Amazing #CMC Session at TIDES! 💥
Insightful presentations, lively discussions and an engaging panel!
I had the privilege of hosting the session and moderating a panel with leading experts in the oligonucleotide field, each sharing their cutting-edge advancements:
Yannick Fillon from Biogen - Scaling up LPOS for manufacturing.
Filippo Sladojevich from Roche -Biocatalytic approaches to oligonucleotide manufacturing and their CMC implications.
Ashish G. from Eli Lilly and Company - Exploring the impact of liquid DS on the DP process and facility.
Letizia Volpe from Novartis – Insights from the Inclisiran DS manufacturing process and facility design.
Joan Malmstrøm from Novo Nordisk – The power of NMR spectroscopy for structure and content analyses of oligos.
We wrapped up the session with an engaging panel where we also discussed:
➡️ Strategic application of #technologies for molecules of different lengths, complexities, and chemistries, as well as market volume demands.
➡️ Operational, logistical and QC aspects in the manufacturing process.
➡️ Opportunities to reduce costs and make oligonucleotide-based medicines more accessible to a broader population.
⏺️ Thank you to Yannick, Filippo, Ashish, Letizia, and Joan for their inspiring contributions, making this session impactful.
⏺️ Thank you to Michael Keenan and Joan Awana for having me there.
⏺️ Thank you to our Regulatory CMC colleagues from the afternoon session Daniel Waschke, Hagen Cramer, René Thürmer, Tracey Burr, Daniela Fischer, Sergey Tsukanov.
⏺️ Thank you to all colleagues in the field for their participation.
With #collaboration and #innovation driving us forward, the future of #oligonucleotides therapeutics is undoubtedly bright.
#Oligonucleotides #RNA #CMC #manufacturing #scienceandtechnology #technology #healthcare #lifesciences Informa Connect