TITLE:
Evolution of Antimicrobial, Antioxidant Potentials and Phytochemical Studies of Three Solvent Extracts of Five Species from Acacia Used in Sudanese Ethnomedicine
AUTHORS:
Hajir B. Abdllha, Alaa I. Mohamed, Khansa A. Almoniem, Naga I. Adam, Wdeea Alhaadi, Ahmed A. Elshikh, Ahmed J. Ali, Ismail G. Makuar, Anas M. Elnazeer, Nagat A. Elrofaei, Samir F. Abdoelftah, Monier N. Hemidan
KEYWORDS:
Antimicrobial, Antioxidant, Phytochemical, Sudanese Ethnomedicine Acacia Species
JOURNAL NAME:
Advances in Microbiology,
Vol.6 No.9,
August
11,
2016
ABSTRACT: The ethanol, chloroform and acetone extracts of five species from Acacia (Acacia albidia stems, Acacia mellifera aerial parts, Acacia
nubica aerial parts, Acacia
seyal var. seyal stems and Acacia
tortilis aerial parts) were investigated for their antimicrobial
activity against two standard bacterial strains of Gram +ve bacteria (Staphylococcus
aureus (ATCC 25923)),
Gram -ve bacteria (Pseudomonas aeruginosa (ATCC 27853)) and standard fungi Candida
albicans (ATCC 90028) using the agar-plate well diffusion method.
The chloroform extract was inactive compared to ethanol and acetone extracts.
But ethanol extracts showed the maximum antimicrobial activity against the test
organism. Amongst the plant species screened, ethanol extract of Acacia
seyal stems showed maximum inhibitory activity (38 mm) and (37 mm) against Staphylococcus
aureus and Candida albicans, respectively. The ethanol, chloroform
and acetone extracts of Acacia mellifera (aerial parts) did not show any
activity against the test organisms. Cholorophorm and acetone extracts via
DPPH, the radical scavenging activities were found to be 91 ± 0.03, 88 ± 0.01
and 85 ± 0.04, respectively. The results of phytochemical screening showed that
all extracts of studied plant contain flavonoids, saponins, terpenoids,
steroids, alkaloids, phenols and tannins.