TITLE:
Highly Regio-Selective Synthesis of β-Amino Alcohol by Reaction with Aniline and Propylene Carbonate in Self Solvent System over Large Pore Zeolite Catalyst
AUTHORS:
Anil K. Kinage, Pravin P. Upare, Anandkumar B. Shivarkar, Sunil P. Gupte
KEYWORDS:
β-Amino Alcohol, Proplylene Carbonate, Zeolite, Catalyst, Chemo-Selectivity
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.1 No.3,
August
31,
2011
ABSTRACT: The nucleophilic ring opening of epoxides with amines is a well known route for the synthesis of β-amino alcohols. The use of carbonates offers significant advantages over epoxides as they are far less hazardous materials, safe for handling, do not require high-pressure equipment and most notably the possibility of solvent less reactions. In this work, utilization of zeolite as host catalyst in the reaction media for synthesis of β-amino alcohols without using solvent is reported.