TITLE:
Pemphigoid Gestational and the Importance of Differential Diagnosis: A Case Report
AUTHORS:
Gabriela Francoes Rostirolla, Carolina Dalla Santa Dal Moro, Karine Cappelletti, Mariana Moreira Rizzolli, Marília Damo, Patrícia Borchardt Bolson, Taciana Cappelletti, Thaís Hunoff Ribeiro
KEYWORDS:
Pemphigus, Pregnancy, Dermatology
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.12 No.11,
November
8,
2022
ABSTRACT: Pemphigoid Gestational (PG), an uncommon autoimmune bullous dermatosis of pregnancy, stands out between the specific
dermatological diseases of the gestational period. Despite being
self-limited and benign, it has a significant impact on women’s health, both
physiologically and psychologically. In addition,
it promotes pathological changes that can be complicated during pregnancy. This paper reports the case of a pregnant
patient with blistering lesions throughout the whole body. The diagnostic
hypothesis initially involved PG and the
specific treatment with corticosteroids was initiated, but after the anatomopathological result of the biopsy there has
been diagnostic confusion with drug hypersensitivity, since clinical and
histological manifestations were exuberant for both pathologies. As the lesions recurred
in the puerperium, due to the corticoid abstention that was administered for
the treatment of the differential diagnosis, a diagnostic review with
immunofluorescence was made and confirmed PG. It is important to establish a
correct diagnosis therefore, in order to improve the quality of care offered to
the mother-baby binomial.