Institute for Cellular and Molecular Medicine

Imagine a world where doctors could accurately track the brain development of children in low- and middle-income countries (LMICs). This research from the University of Pretoria is paving the way for just that! The Problem: Limited Tools: Measuring height and weight is common to understand growth, but it doesn't tell usabout brain development. Expensive Technology: High-powered MRI machines are too expensive and impractical for many LMICs. The Solution: Low-Field MRI: This new technology is portable, affordable, and requires less infrastructure than traditional MRI machines. UNITY Project: This global partnership is exploring how low-field MRI can be used to study brain development in LMICs. Why is this important? - Early Intervention: Understanding brain development can help identify children at risk for developmental delays, allowing for earlier intervention. - Better Health Outcomes: Early intervention can lead to better long-term health and education outcomes for children. - Improved Healthcare: This research could revolutionise how doctors in LMICs diagnose and treat developmental issues. By supporting research like this, we can help create a healthier future for children around the world! https://lnkd.in/dEFtKMcp #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth #GlobalHealth #BrainDevelopment #UNITYProject #MRI #LMICs

University of Pretoria researchers have uncovered valuable information that could help doctors better diagnose and treat oral tumours. By studying the expression of certain proteins, they've developed a more accurate way to distinguish between ameloblastoma (AB) and ameloblastic carcinoma (AC). Key Findings: - Proliferation Index: Higher levels of the Ki-67 protein, a marker of cell growth, were found in ameloblastic carcinomas, indicating faster tumour growth. - Stem Cell Markers: While some stem cell markers were expressed in both types of tumours, the levels were generally higher in ameloblastic carcinomas. Why is this important? Accurate diagnosis is crucial for selecting the right treatment. This research could lead to more effective treatment options for patients with ameloblastic carcinoma. https://lnkd.in/d8xN8Awj. #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth #OralHealth #CancerResearch #UniversityofPretoria #OralPathology

New research is shedding light on potential treatments for neonatal encephalopathy (NE) with suspected hypoxic ischaemic encephalopathy (HIE) , a serious condition affecting newborns. While therapeutic hypothermia remains the golden standard of care, researchers are investigating alternative treatment options, including: - Melatonin: This hormone has shown promise in reducing brain damage in animal studies. - Caffeine Citrate: This stimulant has been used to treat apnoea in premature infants and may also benefit those with HIE. - Stem Cells: Autologous cord blood stem cells are being explored for their potential neuroprotective effects. - Epoetin Alfa: This drug, used to treat anaemia, may also help reduce brain damage in HIE. Allopurinal: This medication, typically used for gout, is being investigated for its potential to protect brain cells. These emerging treatments could offer hope for infants with HIE, especially in regions where therapeutic hypothermia may not be readily available. Read more here:  https://lnkd.in/dqJZUsTb #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth #NeonatalEncephalopathy #HypoxicIschaemicEncephalopathy #BirthAsphixia #HIE #BrainInjury #Newborns #Treatment #Research

Congratulations to Dr. Candice Hendricks! This brilliant University of Pretoria graduate has just earned her PhD in medical immunology and is dedicated to revolutionising paediatric care in South Africa. Dr. Hendricks' research focused on umbilical cord blood units, with the aim of making life-saving stem cell transplants more accessible to children with blood cancers. Her journey from paediatric haematologist and oncologist to clinician-scientist showcases her unwavering commitment to improving the lives of young patients. Key Highlights: - Groundbreaking Research: Dr. Hendricks' work has the potential to significantly impact the treatment of paediatric blood cancers. - Passion for Paediatric Care: Her clinical experience has fuelled her drive to find innovative solutions. - Collaborative Approach: Dr. Hendricks emphasises the importance of teamwork in scientific research. - Mentorship: She is committed to guiding the next generation of clinician-scientists. Join us to celebrate Dr. Hendricks' achievements and support her mission to make a difference in the lives of children across South Africa! https://lnkd.in/dq74fbrz #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth #PediatricCare #StemCellTransplants #MedicalResearch #UniversityofPretoria #UPGraduation

That's right, folks! Professor Michael Pepper has been crowned the #1 scholar in Biology and Biochemistry according to the latest Research.com rankings! This prestigious ranking analyses a massive pool of researchers based on their publications and citations in the field. Professor Pepper's impressive D-index score (a measure of research impact) secured the top spot. Here's what makes this ranking so reliable: - Data-driven: Research.com uses info from trusted sources like OpenAlex and CrossRef for rigorous analysis. - Transparent methodology: Their process is clearly explained, including how they account for researcher contributions and achievements. - Focus on quality: They go beyond numbers with manual profile checks to ensure only credible researchers are included. Why this matters? This ranking helps identify leading experts in various fields, inspiring researchers, companies, and even policymakers. We're so proud of Dr Pepper for this incredible achievement! https://lnkd.in/dBgV5557 #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth #ProfPepper #Research #Science #SouthAfrica #Biology #Biochemistry #TopScholar #Proud

Cell and gene therapies are at the forefront of a medical revolution, promising to redefine how we treat diseases. CAR T-cell therapy and gene therapies are leading the charge. CAR T-cell therapy involves engineering patients' T cells to recognise and attack cancer cells. Gene therapies, on the other hand, involve replacing faulty genes with healthy ones or introducing new genes to treat diseases. These therapies offer hope for patients with a wide range of conditions, from blood cancers to genetic disorders. By targeting the root causes of diseases, they have the potential to provide long-lasting, even curative, treatments. As research continues to advance, we can envision a future where diseases are no longer a barrier to a healthy, fulfilling life. The possibilities are endless. Let's explore the potential of these groundbreaking therapies and work towards a brighter, healthier future for all. https://lnkd.in/eWS5pk7K #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine

Get ready for a healthcare revolution! Artificial intelligence (AI) and gene therapy are joining forces to create personalised treatments tailored to your unique genetic makeup. Imagine a future where your healthcare plan is as individual as you are. With AI's ability to analyse vast amounts of data and gene therapy's potential to target specific genetic issues, we're on the cusp of a new era of personalised medicine. We can embrace this exciting future together! https://lnkd.in/dMG9yWGA #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #HealthRevolution #FutureMedicine #AIandHealth #GeneTherapyRevolution #PrecisionMedicine #InnovationInHealth

Gene therapies and cell-based products are revolutionising healthcare, but limited access is holding back progress. Imagine a world where diseases like cancer and genetic disorders are treated at their root. Together, we can advocate for increased funding and research to make these life-changing treatments accessible to everyone. Join the movement for a healthier, more regenerative future! https://lnkd.in/dXiunfFg #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine

Obesity doesn't affect everyone in the same way. Our research with mice shows that males and females gain weight differently when fed a diet that causes obesity. Males tend to gain weight faster than females. However, regardless of sex, obesity's impact on other organs can be seen early on in the weight gain process, which can later lead to some of the conditions linked to obesity. https://lnkd.in/dJK--jpu #Obesity #ObesityWeek #Weightgain #ObesityandSex #ObesityResearch #UniversityOfPretoria

AI is driving progress, but let's talk ethics! Privacy risks, biased algorithms, and unintended consequences are challenges we're facing. Finding the right balance is key for responsible innovation. Balancing innovation and responsibility is the challenge. Imagine a world where progress is not only fast but also ethical! How do you plan to balance the progression of science while maintaining ethical standards in your practice? https://lnkd.in/dMG9yWGA #HIV #CellularResearch #Africa #ICMM #LifeChangers #FacultyofHealthSciences #ResearchThatMatters #stemcells #transplants #UniversityofPretoria #FacultyofHealthSciences #LifeChangers #UPCellularandMolecularMedicine #EthicalAI #InnovationChallenge